Central Pontine Myelinolysis and Hypokalemic Paralysis as Initial Manifestations of Primary Sjögren's Syndrome: A Rare Electrolyte-Mediated Neurological Presentation. [PDF]
Srinivas R, Gk P.
europepmc +1 more source
Biological Drivers of IMiD‐Induced Peripheral Neuropathy in Multiple Myeloma
ABSTRACT The introduction of immunomodulatory drugs (IMiDs), such as thalidomide, lenalidomide and pomalidomide, have led to significant improvements in multiple myeloma (MM) treatment. Many patients now live 10 years or longer with their disease, making treatment‐related side effects increasingly important.
Sina A. Beer +2 more
wiley +1 more source
Depletion of Microglia Increases Cortical Oligodendrocyte Density During Remyelination. [PDF]
Loo HK +5 more
europepmc +1 more source
Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu +9 more
wiley +1 more source
Stem cell-derived extracellular vesicles as immunomodulatory agents: targeting pathological crosstalk in systemic lupus erythematosus and multiple sclerosis. [PDF]
Yao L +6 more
europepmc +1 more source
Organoids: From Bench to Bedside Applications
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li +6 more
wiley +1 more source
Cuprizone in Peanut Butter: An Alternative Method of Cuprizone Administration to Model Demyelination of the Central Nervous System. [PDF]
Hawker B +4 more
europepmc +1 more source
Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
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Ganoderma lucidum mediates microglial polarization and ameliorates experimental autoimmune encephalomyelitis by reducing oxidative stress and inhibiting NF-κB/STAT3 pathway. [PDF]
Zhang L +6 more
europepmc +1 more source
Effects and Correction of Patient Bulk Motion in Cranial DENSE MRI
ABSTRACT Purpose Applications of DENSE to measure cardiac driven brain tissue pulsations are highly sensitive to bulk patient motion due to the sub‐millimeter displacement encoding required, limiting its accuracy, reproducibility, and use in pediatric and aging populations.
Caroline A. Doctor +4 more
wiley +1 more source

