Results 181 to 190 of about 72,285 (261)
Neuroglia have been extensively profiled using single‐cell genomics, improving our understanding of their dynamics after spinal cord injury. A meta‐analysis of five single‐cell time‐course genomic studies reveals heterogeneity underscoring important challenges for interpretation.
Julio Mejia, Philip J. Horner
wiley +1 more source
Zika virus exacerbates encephalomyelitis by inducing the production of T cell-attracting chemokines in astrocytes. [PDF]
Kamiyama N +12 more
europepmc +1 more source
Lifespan Trajectories of Asymmetry in White Matter Tracts
(A) Large‐scale lifespan modeling of white matter asymmetry. Diffusion MRI data from 35,000+ individuals (0‐100 years) across 50 cohorts were used to generate normative lifespan trajectories of white matter asymmetry. Thirty bilateral tracts were segmented, and microstructural (FA, MD, AD, RD) and macrostructural (volume, length) features were ...
Sam Bogdanov +72 more
wiley +1 more source
Astrocytic TIA1-Mediated Stress Granules Promote the Demyelination of Optic Neuritis by Sequestering mRNA of Cholesterol Synthesis Genes in an Experimental Autoimmune Encephalomyelitis Model. [PDF]
Fang Z +11 more
europepmc +1 more source
Normative voxel‐wise T1 and T2 brain atlases were constructed from 947 healthy adults across 11 imaging centers. The atlases model age‐ and sex‐related trajectories with high intersite reproducibility, providing quantitative reference maps for individual‐level interpretation and harmonized studies of brain aging and neurodegeneration.
Junjie Wang +9 more
wiley +1 more source
Metabolic Symbiosis and Vulnerability in the CNS Axon-Myelin Unit. [PDF]
Miao K +8 more
europepmc +1 more source
Sensorimotor mu‐rhythm phase modulates corticospinal excitability; however, the influence of mu‐phase varies across individuals and could be related to microstructural connectivity between primary somatosensory (S1) and motor (M1) cortices. Our findings suggest that higher S1–M1 microstructural connectivity is associated with a stronger mu‐phase effect
Juliana R. Hougland +4 more
wiley +1 more source
Mechanistic insights from experimental autoimmune encephalomyelitis into immune regulation, autophagy, gut microbiota, blood-brain barrier integrity, and NLRP3 inflammasome-mediated pyroptosis in multiple sclerosis: potential clinical implications. [PDF]
Zhang SM +11 more
europepmc +1 more source
Schematic illustration on a therapeutic strategy wherein engineered extracellular vesicles (EVs) are delivered intranasally and specifically target pericytes. In a model of chronic cerebral hypoperfusion (BCAS), this targeted approach preserves cerebral blood flow, reinforces blood‐brain barrier (BBB) integrity, stabilizes the neurovascular unit (NVU),
Weiwei Shen +11 more
wiley +1 more source

