Results 211 to 220 of about 117,570 (300)

Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Cerebral Cortical Encephalitis: A Comparative Study With Antibody‐Negative and Non‐MOG Antibody‐Positive Cortical Encephalitis in Chinese Adults

CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
MOG antibody‐associated cortical encephalitis (MOG‐CCE) presents a distinct clinical phenotype characterized by seizure‐dominant onset, unilateral cortical lesions, and favorable immunotherapy response, highlighting the diagnostic and prognostic value of antibody profiling in autoimmune cortical encephalitis.
Qing Yin, Binhong Han, Kai Su, Weiqi Dai, Jing Wu, Li Yang, Yuwei Dai, Dan Wang   +7 more
wiley   +1 more source

Trigeminal root demyelination is sufficient to induce trigeminal neuralgia-like facial pain in adult rodents. [PDF]

J Headache Pain
Wang ZY, Ding YQ, Wen JM, Zheng BW, Zhang K, Qi JG.   +5 more
europepmc   +1 more source

The Ubiquitin Ligase Zinc Finger SWIM Domain‐Containing Protein 8 Regulates Oligodendrocyte Development Through the Argonaute2/MicroRNA‐7 Axis

Glia, Volume 74, Issue 5, May 2026.
ZSWIM8, an E3 ubiquitin ligase that broadly targets IDR‐rich proteins, drives MiR‐7‐dependent AGO2 degradation and the turnover of many RBPs. Loss of ZSWIM8 leads to MiR‐7 accumulation in oligodendrocyte progenitor cells and myelination defects in the developing brain. ABSTRACT Proteostasis of proteins with intrinsically disordered regions (IDRs) is of
Jing Lei, Siming Zhong, Rong Fan, Xin Shu, Guan Wang, Jiansheng Guo, Shuting Xue, Luqian Zheng, Aiming Ren, Junfang Ji, Bing Yang, Shumin Duan, Zhiping Wang, Xing Guo   +13 more
wiley   +1 more source

Astrocyte-intrinsic signaling of chitinase-like protein CHI3L1 drives inflammation and amplifies demyelination in neuromyelitis optica. [PDF]

J Clin Invest
Xu H, Jiang W, Xu L, Li H, Yang X, Zhu F, He P, Song Y, Li Y, Huang YA, Qiu W, Tang C.   +11 more
europepmc   +1 more source

Clinical Applications of Electrical Conductivity Imaging Using MRI

Journal of Magnetic Resonance Imaging, Volume 63, Issue 5, Page 1224-1245, May 2026.
ABSTRACT Magnetic resonance imaging (MRI) has emerged as a noninvasive technique for probing the electrical properties of biological tissues: electrical conductivity and relative permittivity. This review focuses on the electrical conductivity and provides a comprehensive overview of applications across both low‐ and high‐frequency regimes.
Stefano Mandija, Khin Khin Tha, Nitish Katoch, Cihan Göksu, Ulrich Katscher, Rosalind Sadleir, Kyu‐Jin Jung, Jierong Luo, Ilias I. Giannakopoulos, Dong‐Hyun Kim, Karin Shmueli, Riccardo Lattanzi, Yusuf Ziya Ider, Axel Thielscher, Cornelis van den Berg   +14 more
wiley   +1 more source

Slowly Expanding Lesions in Multiple Sclerosis: A Systematic Review and Meta-Analysis. [PDF]

NeuroSci
Yazdan Panah M, Fekri M, Zahedi Z, Bagheri H, Vaheb S, Mahmoudi F, Shaygannejad V, Mirmosayyeb O.   +7 more
europepmc   +1 more source

High‐Throughput Screening Reveals That CeeNU Acts as a New NLRP3 Inflammasome Inhibitor

MedComm, Volume 7, Issue 5, May 2026.
We conducted a high‐throughput screen of 2747 FDA‐approved drugs to identify inhibitors of pyroptosis. We found that CeeNU significantly repressed NLRP3‐dependent IL‐1β release and GSDMD pore‐forming complex. We identified that the arginine 335 amino acid of the NACHT domain of NLRP3 is the critical point for human NLRP3 and CeeNU interaction and ...
Sen‐Lin Ji, Peipei Chen, Huaiping Tang, Chao Zhou, Zihao Li, Yunshu Wang, Xiang Cao, Liwen Zhu, Xinyu Bao, Zhuo Liu, Yan Chen, Yun Xu   +11 more
wiley   +1 more source

Osmotic demyelination syndrome diagnosed by Magnetic Resonance Imaging in a child with tetraplegia: Case report. [PDF]

Radiol Case Rep
Domruk ÖF, Almus E, Yılmaz Z, Yapıcı Ö.   +3 more
europepmc   +1 more source

Chronic Pain: Epidemiology, Pathophysiology, and Clinical Management

MedComm, Volume 7, Issue 5, May 2026.
The multidimensional nature of chronic pain is illustrated through four interconnected domains. (Left) Epidemiology and Global Burden: Chronic pain affects approximately one in five individuals globally, contributing to a rising trend in disability‐adjusted life years (YLDs) and a significant socioeconomic impact.
Zhihao Shang, Zijiao Tian, Zhaoquan Wang, Zerui Yang, Ziyao Wang, Zikang Wang, Ziqing Wang, Xingyuan He, Yu Yan, Yuanfeng Gong, Siyuan Xu, Xinyi Li, Guihua Tian   +12 more
wiley   +1 more source

Microglia-derived APOE2 improves remyelination even in the presence of endogenous APOE4. [PDF]

J Neuroinflammation
Nolt GL, Golden LR, Thorpe SP, Funnell JL, Stephens IO, Hernandez G, MacLean SM, Lucido CC, Brock CR, Pallerla AV, Adreon DR, Williams HC, Morganti JM, Johnson LA.   +13 more
europepmc   +1 more source