Results 271 to 280 of about 104,217 (332)

Curcumin-Piperine Self-Nanoemulsifying Delivery in <i>Zanthoxylum rhetsa</i> Seed Oil Attenuates Cuprizone-Induced Frontal Cortex Toxicity. [PDF]

Pharmaceuticals (Basel)
Alam MZ, Bagabir HA, Zaher MAF, Alqurashi TMA, Alghamdi BS, Kazi M, El-Aziz GSA, Alshahrany GA, Alzahrani NA, Bakhalgi RM, Al-Thepyani M, AboTaleb HA, Aldhahri RS, Juweiriya, Ashraf GM.   +14 more
europepmc   +1 more source

Microbial‐Immune Interplay in CNS Autoimmune Diseases: Lessons from Animal Models and Clinical Studies

European Journal of Immunology, Volume 56, Issue 2, February 2026.
Mechanism of action of the intestinal microbiota on CNS autoimmune diseases. Environmental factors shape gut microbiota composition; dysbiosis alters microbial metabolites and antigenic signals. These modulate innate and adaptive immunity, affect barrier integrity, and influence CNS‐resident cells such as microglia and astrocytes, contributing to ...
Matteo Ceccon, Francesca Ronchi
wiley   +1 more source

Herpes simplex virus associated rhomboencephalitis mimicking demyelination: a case report. [PDF]

BMC Infect Dis
Lodha N, Talkar MA, Kumar D, Bhellum P, Kaushik U, Sanga Z, Talreja SD, Garg MK, Yalla H.   +8 more
europepmc   +1 more source

Prolactin Receptor Deficiency Promotes Hypomyelination in White Matter Tracts During Postnatal Central Nervous System Maturation in Mice

Glia, Volume 74, Issue 2, February 2026.
Prolactin action is essential for proper myelination of white matter tracts during neonatal and prepubertal stages in mice. Lack of prolactin receptor (Prlr−/−) signaling leads to hypomyelination and impaired locomotor function. ABSTRACT A large wave of myelination in the central nervous system (CNS) of mammals occurs during postnatal development ...
Ana L. Ocampo‐Ruiz, José L. Dena‐Beltrán, Marco A. Dimas‐Rufino, Ximena Castillo, Dina I. Vazquez‐Carrillo, Andrea Silos‐Guajardo, Xarubet Ruiz‐Herrera, Edith Garay, Gonzalo Martínez de la Escalera, Carmen Clapp, Rogelio O. Arellano, Abraham J. Cisneros‐Mejorado, Yazmín Macotela   +12 more
wiley   +1 more source

Directional Modulation of the Integrated Stress Response in Neurodegeneration: A Systematic Review of eIF2B Activators, PERK-Pathway Agents, and ISR Prolongers. [PDF]

Biomedicines
Stoian II, Nistor D, Levai MC, Popa DI, Popescu R.   +4 more
europepmc   +1 more source

Aberrant Molecular Myelin Architecture in Charcot–Marie–Tooth Disease Type 1A and Hereditary Neuropathy With Liability to Pressure Palsies

Glia, Volume 74, Issue 2, February 2026.
PMP22 copy number variation disrupts myelin architecture at SLIs and Nodes of Ranvier. Adherens junction and axoglial domain defects are often more severe in CMT1A than HNPP. Findings support PMP22 functioning as a structural organizer of myelin. ABSTRACT Charcot–Marie–Tooth Disease Type 1A (CMT1A) and Hereditary Neuropathy with Liability to Pressure ...
Kathryn R. Moss, Marvis A. Arowolo, Dave R. Gutierrez, Ahmet Höke   +3 more
wiley   +1 more source

Post-onset intermittent fasting attenuates neuroinflammation and demyelination via a TRIB3-PERK-autophagy axis in an EAE model of multiple sclerosis. [PDF]

J Neuroinflammation
He W, Liu X, Wang D, Gong Y, Cui T, Zhang X, Li P, Ding X, Yang L, Zhang Q, Yang Y, Xue X, Shi L, Zhang Y, Yan Y.   +14 more
europepmc   +1 more source

Piezo1 activation on microglial cells exacerbates demyelination in sepsis by influencing the CCL25/GRP78 pathway

Di Xie, Yanli Ma, Chengjin Gao, Shuming Pan   +3 more
openalex   +1 more source

Acute Intermittent Hypoxia Exerts Beneficial Effects and Promotes Repair in Male Mice in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis

Glia, Volume 74, Issue 2, February 2026.
Acute intermittent hypoxia is a novel, noninvasive therapy that shows promising and similar beneficial repair and remyelination following demyelination in male experimental autoimmune encephalomyelitis, as was previously shown in female mice. ABSTRACT Multiple sclerosis (MS) affects women more frequently than men, but the disease progresses more ...
Nataliya Tokarska, Josh Roberts, Sameer Rathnayaka Koralage, Justin M. A. Naniong, Jayne M. Johnston, Zelan Wei, Valerie M. K. Verge   +6 more
wiley   +1 more source

Peroxisomal integrity in demyelination-associated microglia enables cellular debris clearance and myelin renewal in mice. [PDF]

J Clin Invest
Barnes-Vélez JA, Zhang X, Peña Señeriz YL, Scott KA, Guan Y, Hu J.   +5 more
europepmc   +1 more source