Superelastic and pH-Responsive Degradable Dendrimer Cryogels Prepared by Cryo-aza-Michael Addition Reaction [PDF]
Dendrimers exhibit super atomistic features by virtue of their well-defined discrete quantized nanoscale structures. Here, we show that hyperbranched amine-terminated polyamidoamine (PAMAM) dendrimer G4.0 reacts with linear polyethylene glycol (PEG ...
Juan Wang, Hu Yang
doaj +4 more sources
COMPUTER MODELING OF INTERACTION OF LYSINE DENDRIMER WITH EPITHALON PEPTIDES [PDF]
Subject of Study.Dendrimers are hyperbranched polymeric molecules that regularly branch from a single center. Dendrimers are used in biomedical applications to deliver drugs and genetic material to cells.
D. N. Khamidova +6 more
doaj +1 more source
Helical micelle of an achiral surfactant from the template interaction with dendrimer
The electrostatic interaction between of poly(amidoamine) (PAMAM) G9 dendrimer and an achiral surfactant, dodecylbenzenesulfonic acid (DBSA), leads to the formation of nucleosome-like structure, where the globular dendrimer molecule directs the DBSA ...
Yi-Cheng Lai +7 more
doaj +1 more source
Synergistic cellular toxicity and uptake effects of iodixanol conjugated to anionic linear globular dendrimer G2 [PDF]
Objective(s): Early diagnosis of cancer using noninvasive imaging techniques has been discussed in several recent studies. The present study aimed to assess the synergistic effects of iodixanol-conjugated polyethylene glycol (PEG)-citrate (anionic linear
Mitra Kiani +2 more
doaj +1 more source
The main objective of this review is to describe the importance of dendrimer prodrugs in the design of new drugs, presenting numerous applications of these nanocomposites in the pharmaceutical field. Therefore, the use of dendrimer prodrugs as carrier for drug delivery, to improve pharmacokinetic properties of prototype, to promote drug sustained ...
Soraya da Silva Santos +2 more
openaire +3 more sources
Structure of poly(propyl ether imine) (PETIM) dendrimer from fully atomistic molecular Dynamics Simulation and by Small Angle X-ray scattering [PDF]
We study the structure of carboxylic acid terminated neutral poly (propyl ether imine) (PETIM) dendrimer from generation 1 through 6 (G1-G6) in a good solvent (water) by fully atomistic molecular dynamics (MD) simulations.
A. K. Sood +8 more
core +2 more sources
Dendrimer-protein interactions versus dendrimer-based nanomedicine [PDF]
Dendrimers are hyperbranched polymers belonging to the huge class of nanomedical devices. Their wide application in biology and medicine requires understanding of the fundamental mechanisms of their interactions with biological systems. Summarizing, electrostatic force plays the predominant role in dendrimer-protein interactions, especially with ...
Shcharbin, Dzmitry +10 more
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Dendrimer-Based Drug Delivery Systems for Brain Targeting
Human neuroscience has made remarkable progress in understanding basic aspects of functional organization; it is a renowned fact that the blood–brain barrier (BBB) impedes the permeation and access of most drugs to central nervous system (CNS) and that ...
Yuefei Zhu, Chunying Liu, Z. Pang
semanticscholar +1 more source
Review Dendrimer : Definisi, Sintesis, Aplikasi Dan Prospektif
Dendrimer merupakan makrostruktur monodisperse dengan banyak cabang yang homogen dan degree of branching (DB) 100%. Dua cara sintesis dendrimer yaitu convergent dan divergent dilakukan.
Dwinna Rahmi
doaj +1 more source
Cytotoxicity of Dendrimers [PDF]
Drug delivery systems are molecular platforms in which an active compound is packed into or loaded on a biocompatible nanoparticle. Such a solution improves the activity of the applied drug or decreases its side effects. Dendrimers are promising molecular platforms for drug delivery due to their unique properties.
Anna Janaszewska +4 more
openaire +4 more sources

