Results 21 to 30 of about 54,440 (362)
Partially glycosylated dendrimers block MD-2 and prevent TLR4-MD-2-LPS complex mediated cytokine responses. [PDF]
PLoS Computational Biology, 2011 The crystal structure of the TLR4-MD-2-LPS complex responsible for triggering powerful pro-inflammatory cytokine responses has recently become available. Central to cell surface complex formation is binding of lipopolysaccharide (LPS) to soluble MD-2. We
Teresa S Barata +4 more
doaj +1 more source
A Density Matrix Renormalization Group study of Excitons in Dendrimers [PDF]
arXiv, 2000 We introduce the density matrix renormalization group (DMRG) method as an efficient computational tool for one-exciton approximations with off-diagonal disorder. This method allows us to reduce the computational effort by targetting only a few low-lying eigenstates at each statistical sampling, in contrast to the exact diagonalization methods that ...
M. A. Martín-Delgado +2 more
openalex +3 more sources
Curcumin encapsulation using dendrimer PAMAM G4 conjugated with polyethylene glycol to improve the properties of gel dossage form [PDF]
Pharmaciana, 2018 Curcumin had a low bioavailability, to improve it than curcumin was encapsulated in the PAMAM dendrimer conjugated PEG. To facilitate topical use, curcumin dendrimer was combined with a carbomer 940 that can produce hydration conditions in the stratum ...
Rahmah Elfiyani +2 more
doaj +1 more source
Dendrimer-protein interactions versus dendrimer-based nanomedicine [PDF]
Colloids and Surfaces B: Biointerfaces, 2017 Dendrimers are hyperbranched polymers belonging to the huge class of nanomedical devices. Their wide application in biology and medicine requires understanding of the fundamental mechanisms of their interactions with biological systems. Summarizing, electrostatic force plays the predominant role in dendrimer-protein interactions, especially with ...
Shcharbin, Dzmitry +10 more
openaire +3 more sources
Structure of DNA-Functionalized Dendrimer Nanoparticles [PDF]
Soft Matter, 2012, 8, 1893-1900, 2012 Atomistic molecular dynamics simulations have been carried out to reveal the characteristic features of ethylenediamine (EDA) cored protonated poly amido amine (PAMAM) dendrimers of generation 3 (G3) and 4 (G4) that are functionalized with single stranded DNAs (ssDNAs).
arxiv +1 more source
Theranostics, 2018 Mitochondrial oxidative stress is associated with many neurodegenerative diseases, such as traumatic brain injury (TBI). Targeted delivery of antioxidants to mitochondria has failed to translate into clinical success due to their nonspecific cellular ...
Anjali Sharma +5 more
semanticscholar +1 more source
Mesoporous Silica Nanoparticles Decorated with Polycationic Dendrimers for Infection Treatment [PDF]
Acta Biomaterialia. 68, 261-271 (2018), 2021 This work aims to provide an effective and novel solution for the treatment of infection by using nanovehicles loaded with antibiotics capable of penetrating the bacterial wall, thus increasing the antimicrobial effectiveness. These nanosystems, named "nanoantibiotics", are composed of mesoporous silica nanoparticles (MSNs), which act as nanocarriers ...
arxiv +1 more source
Turn-on Type Chemical Sensing of Vitamin K4 by Fluorene Dendrimers with Naphthalene Segments
Molecules, 2014 G1 and G2 fluorene dendrimers with naphthalene termini were synthesized as a fluorescence turn-on type chemical sensor for vitamin K4. The fluorene dendrimers were prepared by Williamson ether reaction between the fluorene core with dihydroxy groups and ...
Naoya Adachi +3 more
doaj +1 more source
Binary tree-inspired digital dendrimer
Nature Communications, 2019 Digital polymers with precisely ordered units acting as the coded 0- or 1-bit, are introduced as a promising option for molecular data storage. However, the pursuit of better performance in terms of high storage capacity and useful functions never stops.
Zhihao Huang +10 more
semanticscholar +1 more source
Dendrimer Assisted Dispersion of Carbon Nanotubes: A Molecular Dynamics Study [PDF]
Soft Matter, 2016,12, 8512-8520, 2016 Various unique physical, chemical, mechanical and electronic properties of carbon nanotube (CNT) make it very useful materials for diverse potential application in many fields. Experimentally synthesized CNTs are generally found in bundle geometry with a mixture of different chirality and present a unique challenge to separate them.
arxiv +1 more source