Results 11 to 20 of about 72,289 (292)
Molecules, 2023 Dendrimers have a diverse and versatile morphology, frequently consisting of core, linking, and peripheral moieties. Dendrimers with flexible linkers, such as PAMAM, cannot retain the persistent shape of molecules, and this has been widely explored and ...
Yao-Chih Lu, Roberto Anedda, Long-Li Lai
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The application advances of dendrimers in biomedical field
View, 2023 Dendrimers are a family of nano‐sized three‐dimensional polymers with unique dendritic branching structures and compact spherical geometries. In recent years, dendrimers have made a series of breakthroughs in the biomedical field.
Longjie Li +10 more
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Molecules, 2016 The main objective of this review is to describe the importance of dendrimer prodrugs in the design of new drugs, presenting numerous applications of these nanocomposites in the pharmaceutical field. Therefore, the use of dendrimer prodrugs as carrier for drug delivery, to improve pharmacokinetic properties of prototype, to promote drug sustained ...
Soraya da Silva Santos +2 more
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Dendrimer-based nanocomposites for the production of RNA delivery systems
OpenNano, 2023 A novel approach to treating cancer has been revealed to be effective cancer vaccination. It has also been demonstrated that nucleic acid therapies such as mRNA and siRNA are very efficient in the treatment of cancer.
Chiou Chyi Lim +2 more
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Application of Dendrimers in Anticancer Diagnostics and Therapy
Molecules, 2022 The application of dendrimeric constructs in medical diagnostics and therapeutics is increasing. Dendrimers have attracted attention due to their compact, spherical three-dimensional structures with surfaces that can be modified by the attachment of ...
Zuzanna Bober +2 more
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Practical computational toolkits for dendrimers and dendrons structure design [PDF]
, 2017 Dendrimers and dendrons offer an excellent platform for developing novel drug delivery systems and medicines. The rational design and further development of these repetitively branched systems are restricted by difficulties in scalable synthesis and ...
A Kwok +52 more
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Artificial Cells, Nanomedicine, and Biotechnology, 2019 In the present work, PEG4000 as a hydrophilic polymer was conjugated to the surface of graphene oxide (GO) for effective drug loading and targeting release of doxorubicin.
Mohamad Kazempour +3 more
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Conjugation of Gentamicin to Polyamidoamine Dendrimers Improved Anti-bacterial Properties against Pseudomonas aeruginosa [PDF]
Advanced Pharmaceutical Bulletin, 2021 Purpose: This study aimed to design gentamicin-conjugated poly (amidoamine) (PAMAM) dendrimers to increase the therapeutic efficiency of gentamicin against Pseudomonas aeruginosa.
Hamed Sheykhloo +4 more
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Dendrimer-protein interactions versus dendrimer-based nanomedicine [PDF]
Colloids and Surfaces B: Biointerfaces, 2017 Dendrimers are hyperbranched polymers belonging to the huge class of nanomedical devices. Their wide application in biology and medicine requires understanding of the fundamental mechanisms of their interactions with biological systems. Summarizing, electrostatic force plays the predominant role in dendrimer-protein interactions, especially with ...
Shcharbin, Dzmitry +10 more
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Effect of Terminal Groups of Dendrimers in the Complexation with Antisense Oligonucleotides and Cell Uptake [PDF]
, 2016 Indexación: Web of Science.Poly(amidoamine) dendrimers are the most recognized class of dendrimer. Amino-terminated (PAMAM-NH2) and hydroxyl-terminated (PAMAM-OH) dendrimers of generation 4 are widely used, since they are commercially available.
Araya-Durán, Ingrid +10 more
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