The role of ongoing dendritic oscillations in single-neuron dynamics [PDF]
The dendritic tree contributes significantly to the elementary computations a neuron performs while converting its synaptic inputs into action potential output.
A Alonso+44 more
core +4 more sources
Computational convergence of the path integral for real dendritic morphologies [PDF]
Neurons are characterised by a morphological structure unique amongst biological cells, the core of which is the dendritic tree. The vast number of dendritic geometries, combined with heterogeneous properties of the cell membrane, continue to challenge ...
Brand, Samuel+3 more
core +2 more sources
The dendritic cell niche in chronic obstructive pulmonary disease. [PDF]
The pulmonary innate immune system is heavily implicated in the perpetual airway inflammation and impaired host defense characterizing Chronic Obstructive Pulmonary Disease (COPD).
Haczku, Angela
core +3 more sources
Information Fusion for Anomaly Detection with the Dendritic Cell Algorithm [PDF]
Dendritic cells are antigen presenting cells that provide a vital link between the innate and adaptive immune system, providing the initial detection of pathogenic invaders.
Aickelin, Uwe+2 more
core +3 more sources
MCSF drives regulatory DC development in stromal co-cultures supporting hematopoiesis [PDF]
Background: Splenic stroma overlaid with hematopoietic progenitors supports in vitro hematopoiesis with production of dendritic-like cells. Co-cultures of murine lineage-depleted bone marrow over the 5G3 stromal line produce two populations of cells ...
O'Neill, Helen C+2 more
core +2 more sources
Exact solutions to cable equations in branching neurons with tapering dendrites [PDF]
Neurons are biological cells with uniquely complex dendritic morphologies that are not present in other cell types. Electrical signals in a neuron with branching dendrites can be studied by cable theory which provides a general mathematical modelling ...
Timofeeva, Yulia, Yihe, Lu
core +2 more sources
Putative cell adhesion membrane protein Vstm5 regulates neuronal morphology and migration in the central nervous system [PDF]
During brain development, dynamic changes in neuronal membranes perform critical roles in neuronal morphogenesis and migration to create functional neural circuits.
Ko, Kwang Woo+5 more
core +2 more sources
Direct Inhibition of T-Cell Responses by the Cryptococcus Capsular Polysaccharide Glucuronoxylomannan [PDF]
The major virulence factor of the pathogenic fungi Cryptococcus neoformans and C. gattii is the capsule. Glucuronoxylomannan (GXM), the major component of the capsule, is a high-molecular-weight polysaccharide that is shed during cryptococcosis and can ...
Lam, Jennifer S+2 more
core +4 more sources
Dendritic cells in plasmodium infection [PDF]
Infection with Plasmodium parasites (malaria) contributes greatly to morbidity and mortality in affected areas. Interaction of the protozoan with the immune system has a critical role in the pathogenesis of the disease, but may also hold a key to ...
Alonso+15 more
core +2 more sources
The B subunit of Escherichia coli heat-labile toxin alters the development and antigen-presenting capacity of dendritic cells [PDF]
Escherichia coli’s heat-labile enterotoxin (Etx) and its non-toxic B subunit (EtxB) have been characterized as adjuvants capable of enhancing T cell responses to co-administered antigen.
Griffiths, Kristin L.+4 more
core +1 more source