In this work, the capability of primary, monocyte-derived dendritic cells (DCs) to uptake iron oxide magnetic nanoparticles (MNPs) is assessed and a strategy to induce selective cell death in these MNP-loaded DCs using external alternating magnetic ...
Asín, L. +6 more
core +2 more sources
Summary: Dendritic cells (DCs) populate nearly all tissues and represent the central orchestrators of immunity. Here, we present a protocol for the mild but efficient preparation of single-cell suspensions from multiple murine tissues and the downstream ...
Lukas Amon +7 more
doaj +1 more source
A perspective on cortical layering and layer-spanning neuronal elements [PDF]
This review article addresses the function of the layers of the cerebral cortex. We develop the perspective that cortical layering needs to be understood in terms of its functional anatomy, i.e., the terminations of synaptic inputs on distinct cellular ...
Larkum, Matthew E. +3 more
core +2 more sources
Evolving Dendritic Morphologies Highlight the Impact of Structured Synaptic Inputs on Neuronal Performance [PDF]
Acknowledgements I would like to express my sincere gratitude to Dr.
Kagdi, Mohammad Ziyad
core +1 more source
In Vitro and In Vivo Effects of Ketamine on Generation and Function of Dendritic Cells
.: The question about how intravenous anesthetic reagents affect the development and function of dendritic cell subsets still has no comprehensive answers.
Jingxian Zeng +4 more
doaj +1 more source
Induction of inhibitory central nervous system-derived and stimulatory blood-derived dendritic cells suggests a dual role for granulocyte-macrophage colony-stimulating factor in central nervous system inflammation [PDF]
The mononuclear phagocyte system, particularly dendritic cells, plays several pivotal roles in the development of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis.
Fontana, Adriano +6 more
core
The GDNF-GFRα1 complex promotes the development of hippocampal dendritic arbors and spines via NCAM [PDF]
The formation of synaptic connections during nervous system development requires the precise control of dendrite growth and synapse formation. Although glial cell line-derived neurotrophic factor (GDNF) and its receptor GFRα1 are expressed in the ...
Alsina, Fernando Cruz +5 more
core +2 more sources
Different Life Cycle Stages of Plasmodium falciparum Induce Contrasting Responses in Dendritic Cells
Dendritic cells are key linkers of innate and adaptive immunity. Efficient dendritic cell activation is central to the acquisition of immunity and the efficacy of vaccines.
Xi Zen Yap +11 more
doaj +1 more source
Dendritic Cells and Vaccines [PDF]
Note: Dr. Steinman received the prestigious 2007 Albert Lasker Award for Basic Medical Research for the discovery of dendritic cells. The award committee called him “a scientific sleuth, who without cloak and dagger, uncovered the intelligence-gathering component of our immune system—a monumental achievement in the 200-year history of immunology.” Dr ...
openaire +3 more sources
Contrasting roles of axonal (pyramidal cell) and dendritic (interneuron) electrical coupling in the generation of neuronal network oscillations [PDF]
Electrical coupling between pyramidal cell axons, and between interneuron dendrites, have both been described in the hippocampus. What are the functional roles of the two types of coupling?
Bibbig, A. +7 more
core +2 more sources

