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Dendritic Cells Revisited [PDF]
Annual Review of Immunology, 2021 Dendritic cells (DCs) possess the ability to integrate information about their environment and communicate it to other leukocytes, shaping adaptive and innate immunity. Over the years, a variety of cell types have been called DCs on the basis of phenotypic and functional attributes.
Cabeza-Cabrerizo, Mar +4 more
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Intestinal dendritic cells [PDF]
Current Opinion in Gastroenterology, 2015 The intestinal immune system is constantly exposed to foreign antigens, which for the most part should be tolerated, but the immune system retains the ability to react rapidly and effectively to eliminate pathogens. Dendritic cells are at the front line in maintaining intestinal integrity as they are widely distributed within the intestinal lamina ...
Sylwia Smolinska +4 more
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Plasmacytoid dendritic cells: A dendritic cell in disguise
Molecular Immunology, 2023 Since their discovery, the identity of plasmacytoid dendritic cells (pDCs) has been at the center of a continuous dispute in the field, and their classification as dendritic cells (DCs) has been recently re-challenged. pDCs are different enough from the rest of the DC family members to be considered a lineage of cells on their own. Unlike the exclusive
Rebeca Arroyo Hornero, Juliana Idoyaga
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Dendritic cell metabolism [PDF]
Nature Reviews Immunology, 2014 The past 15 years have seen enormous advances in our understanding of the receptor and signalling systems that allow dendritic cells (DCs) to respond to pathogens or other danger signals and initiate innate and adaptive immune responses. We are now beginning to appreciate that many of these pathways not only stimulate changes in the expression of genes
Pearce, E.J., Everts, B.
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Dendritic Cell Differentiation [PDF]
The Journal of Immunology, 2004 Dauer et al. ([1][1]) presented a method to differentiate CD14+ cells into mature dendritic cells (DC) within 48 h (FastDC). FastDC displayed a DC-like morphology, down-regulated CD14, and induced proliferation of autologous T cells against soluble Ags as efficiently as standard monocyte-derived ...
Curti A +4 more
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Information Fusion for Anomaly Detection with the Dendritic Cell Algorithm [PDF]
, 2010 Dendritic cells are antigen presenting cells that provide a vital link between the innate and adaptive immune system, providing the initial detection of pathogenic invaders.
Aickelin, Uwe +2 more
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The discovery of dendritic cells [PDF]
Journal of Experimental Medicine, 2021 An excerpt from Ralph Steinman’s Harvey Lecture describing the discovery of dendritic cells.
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CD83: Activation Marker for Antigen Presenting Cells and Its Therapeutic Potential
Frontiers in Immunology, 2019 CD83 is a member of the immunoglobulin (Ig) superfamily and is expressed in membrane bound or soluble forms. Membrane CD83 (mCD83) can be detected on a variety of activated immune cells, although it is most highly and stably expressed by mature dendritic
Ziduo Li +13 more
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MCSF drives regulatory DC development in stromal co-cultures supporting hematopoiesis [PDF]
, 2018 Background: Splenic stroma overlaid with hematopoietic progenitors supports in vitro hematopoiesis with production of dendritic-like cells. Co-cultures of murine lineage-depleted bone marrow over the 5G3 stromal line produce two populations of cells ...
O'Neill, Helen C +2 more
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The disabled dendritic cell [PDF]
The FASEB Journal, 2001 Dendritic cells are important antigen-presenting cells of the immune system that induce and modulate immune responses. They interact with T and B lymphocytes as well as with natural killer cells to promote activation and differentiation of these cells.
Reinhold Ramoner +4 more
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