Results 21 to 30 of about 804,900 (360)
The dendritic cell niche in chronic obstructive pulmonary disease. [PDF]
, 2012 The pulmonary innate immune system is heavily implicated in the perpetual airway inflammation and impaired host defense characterizing Chronic Obstructive Pulmonary Disease (COPD).
Haczku, Angela
core +3 more sources
Neoplasia: An International Journal for Oncology Research, 2005 Dendritic cells (DC) have been implicated in the defective function of the immune system during cancer progression. We have demonstrated that patients with cancer have fewer myeloid (CD11c+) and plasmacytoid (CD123hi) DC and a concurrent accumulation of ...
Alberto Pinzon-Charry +5 more
doaj +1 more source
Moving on From Sipuleucel-T: New Dendritic Cell Vaccine Strategies for Prostate Cancer
Frontiers in Immunology, 2021 Tumors evade the immune system though a myriad of mechanisms. Using checkpoint inhibitors to help reprime T cells to recognize tumor has had great success in malignancies including melanoma, lung, and renal cell carcinoma.
Sarah I. M. Sutherland +10 more
doaj +1 more source
Dendritic Cell Differentiation [PDF]
The Journal of Immunology, 2004 Dauer et al. ([1][1]) presented a method to differentiate CD14+ cells into mature dendritic cells (DC) within 48 h (FastDC). FastDC displayed a DC-like morphology, down-regulated CD14, and induced proliferation of autologous T cells against soluble Ags as efficiently as standard monocyte-derived ...
Curti A +4 more
openaire +5 more sources
The discovery of dendritic cells [PDF]
Journal of Experimental Medicine, 2021 An excerpt from Ralph Steinman’s Harvey Lecture describing the discovery of dendritic cells.
openaire +3 more sources
Genome Wide Transcriptome Analysis of Dendritic Cells Identifies Genes with Altered Expression in Psoriasis [PDF]
, 2013 Activation of dendritic cells by different pathogens induces the secretion of proinflammatory mediators resulting in local inflammation. Importantly, innate immunity must be properly controlled, as its continuous activation leads to the development of ...
Filkor, Katalin +6 more
core +8 more sources
CD83: Activation Marker for Antigen Presenting Cells and Its Therapeutic Potential
Frontiers in Immunology, 2019 CD83 is a member of the immunoglobulin (Ig) superfamily and is expressed in membrane bound or soluble forms. Membrane CD83 (mCD83) can be detected on a variety of activated immune cells, although it is most highly and stably expressed by mature dendritic
Ziduo Li +13 more
doaj +1 more source
Dendritic cells in plasmodium infection [PDF]
, 2008 Infection with Plasmodium parasites (malaria) contributes greatly to morbidity and mortality in affected areas. Interaction of the protozoan with the immune system has a critical role in the pathogenesis of the disease, but may also hold a key to ...
Alonso +15 more
core +2 more sources
The disabled dendritic cell [PDF]
The FASEB Journal, 2001 Dendritic cells are important antigen-presenting cells of the immune system that induce and modulate immune responses. They interact with T and B lymphocytes as well as with natural killer cells to promote activation and differentiation of these cells.
Reinhold Ramoner +4 more
openaire +3 more sources
CD300f epitopes are specific targets for acute myeloid leukemia with monocytic differentiation
Molecular Oncology, 2019 Antibody‐based therapy in acute myeloid leukemia (AML) has been marred by significant hematologic toxicity due to targeting of both hematopoietic stem and progenitor cells (HSPCs).
Edward Abadir +14 more
doaj +1 more source