Results 51 to 60 of about 804,900 (360)

Travelling waves in a model of quasi-active dendrites with active spines [PDF]

, 2010
Dendrites, the major components of neurons, have many different types of branching structures and are involved in receiving and integrating thousands of synaptic inputs from other neurons.
Abbott, Alvarez, Baer, Bhatt, Bloodgood, Bressloff, Brown, Cajal, Cook, Coombes, Coombes, Coombes, Coombes, Coombes, Cox, Hodgkin, James, Johnston, Katz, Koch, Larkum, Lord, Magee, Mauro, Mel, Miller, Miller, Narayanan, Scott, Segal, Segev, Shepherd, Spruston, Svoboda, Timofeeva, Timofeeva, Timofeeva, Tsay, Ulrich, Williams, Y. Timofeeva   +40 more
core   +1 more source

Human Dendritic Cell Subset Isolation by Magnetic Bead Sorting: A Protocol to Efficiently Obtain Pure Populations

Bio-Protocol, 2023
Dendritic cells have been investigated for cell-based immunotherapy for various applications. The low abundance of dendritic cells in blood hampers their clinical application, resulting in the use of monocyte-derived dendritic cells as an alternative ...
Georgina Flórez-Grau, Jorge Cuenca Escalona, Helena Lacasta-Mambo, Daphne Roelofs, Johanna Bödder, Ruben Beuk, Gerty Schreibelt, I Jolanda de Vries   +7 more
doaj   +1 more source

Dendritic Cells—Ontogeny—

Allergology International, 2007
Dendritic cells (DC) play key rolls in various aspects of immunity. The functions of DC depend on the subsets as well as their location or activation status. Understanding developmental lineages, precursors and inducing factors for various DC subsets would help their clinical application, but despite extensive efforts, the precise ontogeny of various ...
Masutaka Furue, Satoshi Takeuchi
openaire   +4 more sources

Conventional DCs from Male and Female Lupus-Prone B6.NZM Sle1/Sle2/Sle3 Mice Express an IFN Signature and Have a Higher Immunometabolism That Are Enhanced by Estrogen

Journal of Immunology Research, 2018
Type I interferons (IFN) are pathogenic in systemic lupus erythematosus (SLE) and were proposed to control the immunometabolism of dendritic cells (DCs).
Michael H. Lee, Marita Chakhtoura, Uma Sriram, Roberto Caricchio, Stefania Gallucci   +4 more
doaj   +1 more source

The involvement of actin, calcium channels and exocytosis proteins in somato-dendritic oxytocin and vasopressin release [PDF]

, 2012
Hypothalamic magnocellular neurons release vasopressin and oxytocin not only from their axon terminals into the blood, but also from their somata and dendrites into the extracellular space of the brain, and this can be regulated independently ...
Leng, Gareth, Ludwig, Mike, Tobin, Vicky
core   +2 more sources

Milieu intérieur: Defining the boundaries of a healthy immune response for improved vaccination strategies

Human Vaccines & Immunotherapeutics, 2018
Immune responses in human populations are highly variable, with this variability presenting challenges for vaccine design. As such a better understanding of the factors that determine this variability will help in the development of precision vaccination
Darragh Duffy
doaj   +1 more source

Deconvolution of the Response to Bacillus Calmette–Guérin Reveals NF-κB-Induced Cytokines As Autocrine Mediators of Innate Immunity

Frontiers in Immunology, 2017
Bacillus Calmette–Guérin (BCG) is used as a vaccine and diagnostic test for tuberculosis, as well as immunotherapy in the treatment of bladder cancer. While clinically useful, the response to mycobacterial stimulation is complex and the induced protein ...
Aurélie Bisiaux, Aurélie Bisiaux, Jeremy Boussier, Jeremy Boussier, Jeremy Boussier, Darragh Duffy, Darragh Duffy, Lluis Quintana-Murci, Lluis Quintana-Murci, Magnus Fontes, Matthew L. Albert, Matthew L. Albert, Matthew L. Albert, The Milieu Intérieur Consortium   +13 more
doaj   +1 more source

CLEC10A Is a Specific Marker for Human CD1c+ Dendritic Cells and Enhances Their Toll-Like Receptor 7/8-Induced Cytokine Secretion

Frontiers in Immunology, 2018
Dendritic cells (DCs) are major players for the induction of immune responses. Apart from plasmacytoid DCs (pDCs), human DCs can be categorized into two types of conventional DCs: CD141+ DCs (cDC1) and CD1c+ DCs (cDC2).
Lukas Heger, Silke Balk, Jennifer J. Lühr, Gordon F. Heidkamp, Christian H. K. Lehmann, Lukas Hatscher, Ariawan Purbojo, Arndt Hartmann, Fayna Garcia-Martin, Shin-Ichiro Nishimura, Robert Cesnjevar, Falk Nimmerjahn, Diana Dudziak   +12 more
doaj   +1 more source

IOX1 activity as sepsis therapy and an antibiotic against multidrug-resistant bacteria

Scientific Reports, 2021
Sepsis is caused by organ dysfunction initiated by an unrestrained host immune response to infection. The emergence of antibiotic-resistant bacteria has rapidly increased in the last decades and has stimulated a firm research platform to combat ...
Su Jin Lee, Jueng Soo You, Amal Gharbi, Yong Joo Kim, Mi Suk Lee, Dong Hwan Kim, Keun Woo Lee, In Duk Jung, Yeong Min Park   +8 more
doaj   +1 more source

Dendritic Cells in Atherosclerosis [PDF]

Current Pharmaceutical Design, 2013
It is recognized that the development of atherosclerosis involves many elements of an inflammatory process, involving components of both the innate and adaptive immune systems. The presence and roles of macrophages and T-cells in atherogenesis are well-established.
Wendy Jessup, Siân P. Cartland
openaire   +5 more sources