Results 71 to 80 of about 5,439,323 (304)

Dendritic calcium accumulation associated with direction-selective adaptation in visual motion-sensitive neurons in vivo [PDF]

, 2000
Kurtz R, Dürr V, Egelhaaf M. Dendritic calcium accumulation associated with direction-selective adaptation in visual motion-sensitive neurons in vivo. Journal of Neurophysiology.
Egelhaaf, Martin ; https://orcid.org/, Rafael Kurtz, Martin Egelhaaf, Martin Egelhaaf Dendritic Calcium, Kurtz, Rafael, Dürr, Volker ; https://orcid.org/, Volker Dürr   +6 more
core   +1 more source

Ethyl Pyruvate Modulates Murine Dendritic Cell Activation and Survival Through Their Immunometabolism

Frontiers in Immunology, 2019
Attenuating the innate immunity activation could ameliorate inflammation and disease in settings such as transplant rejection or autoimmunity. Recently, a pivotal role for metabolic re-programming in TLR-induced dendritic cell (DC) activation has emerged.
Marita Chakhtoura, Robert W. Chain, Priscila Y. Sato, Priscila Y. Sato, Connie C. Qiu, Michael H. Lee, Joseph J. Meissler, Joseph J. Meissler, Toby K. Eisenstein, Toby K. Eisenstein, Walter J. Koch, Walter J. Koch, Roberto Caricchio, Stefania Gallucci   +13 more
doaj   +1 more source

Loading of Primary Human T Lymphocytes with Citrate-Coated Superparamagnetic Iron Oxide Nanoparticles Does Not Impair Their Activation after Polyclonal Stimulation

Cells, 2020
For the conversion of immunologically cold tumors, characterized by a low T cell infiltration, into hot tumors, it is necessary to enrich T cells in the tumor area. One possibility is the use of magnetic fields to direct T cells into the tumor.
Marina Mühlberger, Harald Unterweger, Julia Band, Christian Lehmann, Lukas Heger, Diana Dudziak, Christoph Alexiou, Geoffrey Lee, Christina Janko   +8 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Dendritic spikes control synaptic plasticity and somatic output in cerebellar Purkinje cells. [PDF]

, 2007
Neurons receive the vast majority of their input onto their dendrites. Dendrites express a plethora of voltage-gated channels. Regenerative, local events in dendrites and their role in the information transformation in single neurons are, however, poorly
Rancz, E.A., Rancz, Ede Attila
core  

Genome Wide Transcriptome Analysis of Dendritic Cells Identifies Genes with Altered Expression in Psoriasis [PDF]

, 2013
Activation of dendritic cells by different pathogens induces the secretion of proinflammatory mediators resulting in local inflammation. Importantly, innate immunity must be properly controlled, as its continuous activation leads to the development of ...
Szász, András, István Nagy (147904), Vilmos Tubak (455817), Kemény Lajos, Kondorosi, Éva, András Szász, Zoltán Hegedűs (455815), Tubak Vilmos, Lajos Kemény, Éva Kondorosi (3507242), Kata Filkor (455814), Kondorosi Éva, Nagy István, Tubák, Vilmos, Lajos Kemény (229288), Hegedűs Zoltán, Szász András, István Nagy, Kemény, Lajos, Éva Kondorosi, Nagy, István, Filkor, Katalin, Vilmos Tubak, Filkor Kata, Hegedűs, Zoltán, András Szász (455816), Kata Filkor, Zoltán Hegedűs   +27 more
core   +2 more sources

Cathepsin S provokes interleukin-6 (IL-6) trans-signaling through cleavage of the IL-6 receptor in vitro

Scientific Reports, 2020
The cytokine interleukin-6 (IL-6) fulfills its pleiotropic functions via different modes of signaling. Regenerative and anti-inflammatory activities are mediated via classic signaling, in which IL-6 binds to the membrane-bound IL-6 receptor (IL-6R).
Charlotte M. Flynn, Yvonne Garbers, Stefan Düsterhöft, Rielana Wichert, Juliane Lokau, Christian H. K. Lehmann, Diana Dudziak, Bernd Schröder, Christoph Becker-Pauly, Stefan Rose-John, Samadhi Aparicio-Siegmund, Christoph Garbers   +11 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

oxLDL downregulates the dendritic cell homing factors CCR7 and CCL21 [PDF]

, 2012
Dendritic cells (DCs) and oxLDL play an important role in the atherosclerotic process with DCs accumulating in the plaques during plaque progression.
Korbinian Lackermair, Kopp, Reinhard, Beiras-Fernandez, Andres, Kaczmarek, Ingo, Summo, Claudia, Andres Beiras-Fernandez, Weis, Michael, Robert David, Michael Weis, Marius Lambert, Thomas Nickel, Ingo Kaczmarek, Claudia Summo, Sicic, Zeljka, Georgios Meimarakis, Lackermair, Korbinian, Lambert, Marius, Nickel, Thomas, Susanne Pfeiler, Pfeiler, Susanne, Meimarakis, Georgios, Reinhard Kopp, Lackermair, Korbinian Johannes, Beiras Fernández, Andrés, Zeljka Sicic, David, Robert   +25 more
core   +1 more source

T-Cell Stimulation by Melanoma RNA-Pulsed Dendritic Cells [PDF]

, 2004
In situations where well-established approaches such as surgery, radiation therapy and chemotherapy fail to help cancer patients, immunotherapy has the potential to be an effective alternative.
Javorovic, Miran
core   +1 more source