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Dendritic Cell Biology

2005
Dendritic cells (DCs) are a special type of leukocytes able to alert the immune system to the presence of infections. They play a central role in the initiation of both innate and adaptive immune responses. This particular DC feature is regulated by the activation of specific receptors at the cell surface called Toll-like receptors (TLRs) that bind a ...
GRANUCCI, FRANCESCA   +2 more
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Intrathyroidal Dendritic Cells*

The Journal of Clinical Endocrinology & Metabolism, 1988
The presence, marker pattern, and ultrastructure of antigen-presenting dendritic cells were studied in normal thyroid glands from 9 subjects (6 obtained at surgery; 3 at autopsy) and in the thyroid glands form 13 patients with Graves' hyperthyroidism, 10 patients with simple nontoxic goiter, and 1 patient with Hashimoto's disease (all obtained at ...
P J, Kabel   +4 more
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Sepsis and the Dendritic Cell

Shock, 2003
Sepsis is a syndrome of significant morbidity and mortality. Unlike the advances made in other diseases processes, improvements in outcome from sepsis, severe sepsis, and septic shock have been modest. Current research has altered our understanding of sepsis pathogenesis such that present models and definitions are still evolving.
Philip, Efron, Lyle L, Moldawer
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Dendritic Cells and Dendritic Cell Subsets

2016
© 2016 Elsevier Ltd All rights reserved. Dendritic cells (DCs) are specialized antigen-presenting cells that may arise naturally from common DC progenitors in the bone marrow or develop from monocytes during inflammation. Migratory DCs arrive in lymph nodes (LNs) from the tissues, while LN-resident DCs are recruited from the blood.
Collin M, Haniffa M
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Dendritic cell ontogeny

Research in Immunology, 1989
Abundant evidence indicates that dendritic cells arise from the bone marrow. In vitro, precursors that differ phenotypically from mature dendritic cells divide several times to form functional dendritic cells. A soluble factor(s) produced in the supernatants of ConA-stimulated spleen cells enhances the production of dendritic cells.
W E, Bowers, E M, Goodell
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Dendritic Cells

The Cancer Journal, 2011
Dendritic cells (DCs) control the initiation and differentiation of T cells. In the steady state, DCs mediate tolerance. To achieve immunization, the tolerogenic function of DCs must be switched off by inducing their maturation with appropriate "adjuvants." Dendritic cells form a system composed of distinct subsets that differ in their expression of ...
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Immunobiology of Dendritic Cells

Annual Review of Immunology, 2000
Dendritic cells (DCs) are antigen-presenting cells with a unique ability to induce primary immune responses. DCs capture and transfer information from the outside world to the cells of the adaptive immune system. DCs are not only critical for the induction of primary immune responses, but may also be important for the induction of immunological ...
J, Banchereau   +7 more
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Follicular dendritic cells

Journal of Cellular Physiology, 2021
AbstractFollicular dendritic cells (FDCs) are unique accessory immune cells that contribute to the regulation of humoral immunity. They are multitasker cells essential for the organization and maintenance of the lymphoid architecture, induction of germinal center reaction, production of B memory cells, and protection from autoimmune disorders.
Seham A. Abd El‐Aleem   +5 more
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Dendritic cells in glomerulonephritis

Virchows Archiv B Cell Pathology Including Molecular Pathology, 1992
Renal biopsies (n = 45) from patients with various forms of glomerulonephritis (GN), comprising mesangial IgA-GN (n = 25), focal glomerular sclerosis (n = 13) and acute GN (n = 7), were examined by double staining immunocytochemistry (APAAP, streptavidin-peroxidase) using unconjugated monoclonal antibodies (Ab) against--(i) the CD1b antigen expressed ...
Čužić, Snježana   +2 more
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Follicular Dendritic Cells and Dendritic Cell Nomenclature

1993
In the 10 years since the last nomenclature committee on dendritic cells met (Tew, Thorbecke and Steinman, J. Reticuloendothelial Society 31:371, 1982), considerable evidence has accumulated supporting the concept that Langerhans cells, interdigitating cells, and veiled cells are the same cell in different stages of maturation. It also appears that the
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