Results 271 to 280 of about 11,507,286 (389)

High Concentrations of β₂-Microglobulin Do Not Inhibit In Vitro Generation of Functional Dendritic Cells. [PDF]

J Immunol Res
Taborska P, Stakheev D, Krausova K, Bartunkova J, Smrz D.   +4 more
europepmc   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Inducible immortalized Dendritic Cells enable antigen-specific antibody production in a murine in vitro Immunization model. [PDF]

PLoS One
Egert J, Maier N, Micheel B, Hanack K.
europepmc   +1 more source

Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells

Nature, 2018
Xingrong Du, Jing Wen, Yanyan Wang, Peer W F Karmaus, Alireza Khatamian, Haiyan Tan, Yuxin Li, C. Guy, Thanh-Long M. Nguyen, Yogesh Dhungana, G. Neale, Junmin Peng, Jiyang Yu, H. Chi   +13 more
semanticscholar   +1 more source

Synthetic Cell‐Based Tissues for Bottom‐Up Assembly of Artificial Lymphatic Organs

Advanced Healthcare Materials, EarlyView.
Synthetic cells have emerged as a novel biomimetic approach for fundamental research and therapeutic interventions. T cell activating synthetic cells are able to form 3D tissue‐like structures by self‐assembly into lymphatic bottom‐up tissues (lymphBUT) with tunable biochemical and biomechanical functionalities as well as metabolic activity are ...
Anna Burgstaller, Tamara Nink, Niklas Walter, Erick Angel Lopez Lopez, Hsin‐Fang Chang, Oskar Staufer   +5 more
wiley   +1 more source

Dupilumab opens a therapeutic window in food protein-induced enterocolitis syndrome by unlicensing dendritic cells. [PDF]

J Allergy Clin Immunol Glob
Plassmeyer M, Enav N, Girgis M, Paige M, Todd L, Israni L, Alpan O.   +6 more
europepmc   +1 more source

Human fetal dendritic cells promote prenatal T-cell immune suppression through arginase-2

Nature, 2017
N. McGovern, A. Shin, G. Low, Donovan Low, Kaibo Duan, L. Yao, Rasha Msallam, Ivy Low, Nurhidaya Binte Shadan, Hermi Sumatoh, Erin Soon, Josephine Lum, E. Mok, Sandra Hubert, Peter See, Edwin Huang Kunxiang, Yie Hou Lee, B. Janela, M. Choolani, C. Mattar, Yiping Fan, T. Lim, D. Chan, K. Tan, J. Tam, C. Schuster, A. Elbe-Bürger, Xiao‐nong Wang, V. Bigley, M. Collin, M. Haniffa, A. Schlitzer, M. Poidinger, S. Albani, A. Larbi, E. Newell, J. Chan, F. Ginhoux   +37 more
semanticscholar   +1 more source

Enhancing Magnetic Hyperthermia at the Cell Membrane by Anchoring 92R‐Functionalized Magnetic Nanoparticles to Low‐Endocytic CCR9 Surface Receptors

Advanced Healthcare Materials, EarlyView.
We present a strategy to enhance magnetic hyperthermia therapy by modulating nanoparticle–cell interactions. Antibody‐functionalized magnetic nanoparticles targeting the low‐internalizing CCR9 receptor enable spatially controlled membrane anchoring, reducing aggregation and maximizing heat generation under alternating magnetic fields.
David Egea‐Benavente, Isabel Corraliza‐Gorjón, Thomas S. van Zanten, María del Puerto Morales, Leonor Kremer, Domingo F. Barber   +5 more
wiley   +1 more source

Molecular Simulations of Polymer‐based Drug Nanocarriers: From Physical and Structural Properties to Controlled Release

Advanced Healthcare Materials, EarlyView.
Polymer‐based drug delivery systems can effectively overcome the limitations of free drugs in terms of solubility, stability, and plasma half‐life, yet their development has traditionally relied on time‐consuming trial‐and‐error approaches. This review highlights recent advances in applying molecular simulation to the design of polymer‐based drug ...
Ping Gao, Xin Jiang, Jinyu Li, Julien Nicolas, Tâp Ha‐Duong   +4 more
wiley   +1 more source

Antigen-specific B cell response regulation by IL-10-producing tolerogenic dendritic cells. [PDF]

Sci Adv
Morali K, Steuten J, Russo F, Romana Santoni de Sio F, Menage C, Consoli V, Annoni A, Iaia S, van Ham SM, Ten Brinke A, Gregori S.   +10 more
europepmc   +1 more source