Results 91 to 100 of about 221,816 (215)
Rare Metals, EarlyView.ABSTRACT This study introduces novel nonequiatomic TiZrCoCrMoCux (x = 0, 5, 10; at%) medium‐entropy alloys (MEAx) tailored for orthopedic implants, synergistically combining the biocompatibility of Ti‐based alloys, the wear resistance of CoCrMo alloys, and the antibacterial/osteogenic attributes of Cu. The alloy's microstructure, mechanical properties,
Hang Yu +9 more
wiley +1 more source
Exosome-mediated Transfer of αvβ3 Integrin from Tumorigenic to Nontumorigenic Cells Promotes a Migratory Phenotype. [PDF]
, 2016 The αvβ3 integrin is known to be highly upregulated during cancer progression and promotes a migratory and metastatic phenotype in many types of tumors.
Fedele, Carmine +5 more
core +2 more sources
The Journal of Physiology, EarlyView.Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley +1 more source
Frontiers in Cellular Neuroscience, 2021 In contrast to the prenatal topographic development of sensory cortices, striatal circuit organization is slow and requires the functional maturation of cortical and thalamic excitatory inputs throughout the first postnatal month.
Naila Kuhlmann +7 more
doaj +1 more source
The Spacing Effect for Structural Synaptic Plasticity Provides Specificity and Precision in Plastic Changes [PDF]
, 2017 In contrast to trials of training without intervals (massed training), training trials spaced over time (spaced training) induce a more persistent memory identified as long-term memory (LTM).
Gelb, Bruce +3 more
core +1 more source
Spatio‐Temporal Diversity of Calcium Activity in Microglia
Glia, Volume 74, Issue 3, March 2026.Ca2+ activity mostly occurs in microglial processes and stays localized. When it spreads, it often shows a directional bias and is constrained by branch points. Activity strongly relies on P2Y12 receptors and is shaped by neuronal activity. ABSTRACT Microglia, the brain's innate immune cells, possess complex, highly motile branched processes. These act
Hiroshi Horiuchi +3 more
wiley +1 more source
Inka2, a novel Pak4 inhibitor, regulates actin dynamics in neuronal development.
PLoS Genetics, 2022 The actin filament is a fundamental part of the cytoskeleton defining cell morphology and regulating various physiological processes, including filopodia formation and dendritic spinogenesis of neurons.
Seiya Yamada +3 more
doaj +1 more source
Disease Models & Mechanisms, 2022 Dendritic spines are the principal site of excitatory synapse formation in the human brain. Several neurodevelopmental disorders cause spines to develop abnormally, resulting in altered spine number and morphology.
Elisabeth C. DeMarco +2 more
doaj +1 more source
Granulocyte-activating mediators (GRAM) [PDF]
, 1988 In the present study we investigated the capability of human epidermal cells to generate granulocyte-activating mediators (GRAM). It could be shown that human epidermal cells as well as an epidermoid carcinoma cell line (A431) produce an epidermal cell ...
Kapp, A. +3 more
core +1 more source
The FASEB Journal, Volume 40, Issue 1, 15 January 2026.BWCFF, a severe disease with neurological symptoms, is caused by mutations in the cytoskeletal actin genes. Patient‐derived fibroblasts carrying the R196H β‐actin mutation were compared to wild type cells. The mutant cells displayed slower proliferation and migration and a lower F‐actin content, which correlated with reduced cell stiffness ...
Éva Gráczer +12 more
wiley +1 more source