Results 181 to 190 of about 221,816 (215)
Dysregulation of astrocyte-secreted pleiotrophin contributes to neuronal structural and functional deficits in Down syndrome. [PDF]
Cell RepBrandebura AN +6 more
europepmc +1 more source
Purification of the Dendritic Filopodia-rich Fraction
Journal of Visualized Experiments, 2019 Dendritic filopodia are thin and long protrusions based on the actin filament, and they extend and retract as if searching for a target axon. When the dendritic filopodia establish contact with a target axon, they begin maturing into spines, leading to ...
Yutaka Furutani, Yoshihiro Yoshihara
semanticscholar +5 more sources
Local calcium transients regulate the spontaneous motility of dendritic filopodia
Nature Neuroscience, 2005 During development, dendrites, and in particular dendritic filopodia, undergo extensive structural remodeling, presumably to help establish synaptic contacts. Here, we investigated the role of calcium signaling in dendritic plasticity by simultaneously recording calcium dynamics and filopodial growth in rat hippocampal slice cultures.
Christian Löhmann +2 more
semanticscholar +5 more sources
Pyroptotic corpses are flagged by filopodia to alert dendritic cells
Nature Immunologysemanticscholar +4 more sources
Gabapentin-Lactam Induces Dendritic Filopodia and Motility in Cultured Hippocampal Neurons
The Journal of Pharmacology and Experimental Therapeutics, 2006 Gabapentin is currently used as a therapeutic agent against epilepsy as well as neuropathic pain. In contrast to gabapentin, its derivative gabapentin-lactam has a pronounced neuroprotective activity. We have studied in cultured hippocampal neurons whether gabapentin-lactam has also neurotrophic effects.
Frank Henle +6 more
semanticscholar +5 more sources
Actomyosin Contractility and Actin Polymerization Explain Dynamic Behavior of Dendritic Filopodia [PDF]
Biophysical Journal, 2013 Dendritic filopodia are actin-filled highly dynamic subcellular structures that sprout densely on neuronal dendrites during early brain development. A fraction of filopodia undergo a transition to dendritic spines that later mature into synapses - a process crucial for memory formation and learning, and deficient in neurodevelopmental and ...
O. Marchenko, C. Wolgemuth, L. Loew
semanticscholar +2 more sources
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Proteomic analysis of dendritic filopodia
Neuroscience Research, 2010Y. Furutani, Y. Yoshihara
semanticscholar +2 more sources