Results 191 to 200 of about 221,816 (215)
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Nano letters (Print), 2022
Dendritic cells (DCs) can infiltrate tight junctions of the epithelium to collect remote antigens during immune surveillance. While membrane filopodia represent a plausible structure to perform this task, their functional mechanisms remain elusive owing ...
Haoran Jing +5 more
semanticscholar +1 more source
Dendritic cells (DCs) can infiltrate tight junctions of the epithelium to collect remote antigens during immune surveillance. While membrane filopodia represent a plausible structure to perform this task, their functional mechanisms remain elusive owing ...
Haoran Jing +5 more
semanticscholar +1 more source
P2X7 Activation Induces Novel Dendritic Cell Filopodia (36.23)
The Journal of Immunology, 2007Abstract Dendritic cells (DC) express multiple surface purinergic receptors that bind extracellular adenosine triphosphate (ATPe) resulting in complex changes in cell morphology and function. We demonstrate that ATPe induces rapid extension of filopodia from cultured DC that are distinct from pre-existing dendritic processes.
Louis Michael Thomas +3 more
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F-dynamics: Automated quantification of dendrite filopodia dynamics in living neurons
Journal of Neuroscience Methods, 2014Dendritic filopodia are highly motile and flexible protrusions that explore the surroundings in search for an appropriate presynaptic partner. Dendritic filopodia morphologically and functionally transform into postsynaptic dendritic spines, once the appropriate partner has been chosen. Therefore, proper formation of synapses depends on the dynamics of
Rita, Hendricusdottir +1 more
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Clustering transmembrane-agrin induces filopodia-like processes on axons and dendrites
Molecular and Cellular Neuroscience, 2006The transmembrane form of agrin (TM-agrin) is primarily expressed in the CNS, particularly on neurites. To analyze its function, we clustered TM-agrin on neurons using anti-agrin antibodies. On axons from the chick CNS and PNS as well as on axons and dendrites from mouse hippocampal neurons anti-agrin antibodies induced the dose- and time-dependent ...
Annies, M. +8 more
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Journal of Physiology
Synapses are essential for neural information processing by gating the propagation of activity in synaptically connected neuronal circuits. During the development of such circuits, neuronal activity contributes to synaptic formation and stabilization, or
Hui-Jing Liu +5 more
semanticscholar +1 more source
Synapses are essential for neural information processing by gating the propagation of activity in synaptically connected neuronal circuits. During the development of such circuits, neuronal activity contributes to synaptic formation and stabilization, or
Hui-Jing Liu +5 more
semanticscholar +1 more source
SSRN Electronic Journal, 2022
SUMMARYNeurons form cell type-specific morphologies that are shaped by molecular cues and their cellular events governing dendrite growth. One growth rule is distributing dendrites uniformly within a neuron’s territory by avoiding sibling or ‘self’ branches.
Samantha Ing-Esteves, Julie L. Lefebvre
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SUMMARYNeurons form cell type-specific morphologies that are shaped by molecular cues and their cellular events governing dendrite growth. One growth rule is distributing dendrites uniformly within a neuron’s territory by avoiding sibling or ‘self’ branches.
Samantha Ing-Esteves, Julie L. Lefebvre
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[On the function of dendritic filopodia].
Revista de neurologia, 2002Dendritic spines were first described by Ramón y Cajal in 1888, and considered by him to be the major sites of axo dendritic apposition and therefore of synaptic input in the CNS. Although a considerable wealth of information has been gathered over the last few decades about the function of spines in the mature nervous system, much less is known about ...
C, Portera Cailliau, R, Yuste
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Dendritic growth cone and filopodia formation as a mechanism of spinal cord regeration
Experimental Neurology, 1977Abstract Following hemisection of the rat spinal cord at the T1–T2 vertebral interface, dendritic sprouting was observed on neurons in the motoneuron pool at 45 days postoperative. The sprouting resulted in increased numbers of dendritic terminals, dendritic growth cones, and dendritic filopodial growth.
M E, Bernstein, J J, Bernstein
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Proceedings of the National Academy of Sciences, 2021
Significance Cellular signaling pathways respond to a wide range of stimuli. How signaling circuits are activated without an instructive stimulus and what this is good for are less clear. Combining theoretical and experimental approaches, we show that curvature-sensing proteins stabilize stochastic membrane deformations to nucleate a self ...
Gloria Mancinelli +9 more
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Significance Cellular signaling pathways respond to a wide range of stimuli. How signaling circuits are activated without an instructive stimulus and what this is good for are less clear. Combining theoretical and experimental approaches, we show that curvature-sensing proteins stabilize stochastic membrane deformations to nucleate a self ...
Gloria Mancinelli +9 more
openaire +2 more sources
Intercellular communication in the brain through a dendritic nanotubular network.
ScienceIntercellular nanotubular networks mediate material exchange, but their existence in neurons remains to be explored in detail. We identified long, thin dendritic filopodia forming direct dendrite-dendrite nanotubes (DNTs) in mammalian cortex.
Minhyeok Chang +8 more
semanticscholar +1 more source