Results 71 to 80 of about 221,816 (215)

Protein tyrosine phosphatase PTP1B is involved in hippocampal synapse formation and learning. [PDF]

PLoS ONE, 2012
ER-bound PTP1B is expressed in hippocampal neurons, and accumulates among neurite contacts. PTP1B dephosphorylates ß-catenin in N-cadherin complexes ensuring cell-cell adhesion.
Federico Fuentes, Derek Zimmer, Marybless Atienza, Jamie Schottenfeld, Ian Penkala, Tracy Bale, Kendra K Bence, Carlos O Arregui   +7 more
doaj   +1 more source

BACE1 modulates filopodia-like protrusions induced by sodium channel β4 subunit [PDF]

, 2007
journal ...
Kaneko Kumi, Miyazaki Haruko, Nukina Nobuyuki, Oyama Fumitaka, Sakurai Takashi, TAMAOKA Akira, Wong Hon-Kit   +6 more
core   +1 more source

A Bright, Nontoxic, and Non-aggregating red Fluorescent Protein for Long-Term Labeling of Fine Structures in Neurons

Frontiers in Cell and Developmental Biology, 2022
Red fluorescent proteins are useful as morphological markers in neurons, often complementing green fluorescent protein-based probes of neuronal activity. However, commonly used red fluorescent proteins show aggregation and toxicity in neurons or are dim.
Lin Ning, Yang Geng, Yang Geng, Matthew Lovett-Barron, Xiaoman Niu, Mengying Deng, Liang Wang, Niloufar Ataie, Alex Sens, Ho-Leung Ng, Shoudeng Chen, Karl Deisseroth, Michael Z. Lin, Michael Z. Lin, Jun Chu   +14 more
doaj   +1 more source

Insights into the origin of metazoan filopodia and microvilli. [PDF]

, 2013
Filopodia are fine actin-based cellular projections used for both environmental sensing and cell motility, and they are essential organelles for metazoan cells. In this study, we reconstruct the origin of metazoan filopodia and microvilli.
Burkhardt, Pawel, Fairclough, Stephen, KING, Nicole, Lang, B, Ruiz-Trillo, Iñaki, Sebé-Pedrós, Arnau, Sánchez-Pons, Núria   +6 more
core   +2 more sources

The RhoGEF trio functions in sculpting class specific dendrite morphogenesis in Drosophila sensory neurons.

PLoS ONE, 2012
BackgroundAs the primary sites of synaptic or sensory input in the nervous system, dendrites play an essential role in processing neuronal and sensory information.
Srividya Chandramouli Iyer, Dennis Wang, Dennis Wang, Eswar Prasad R Iyer, Sarah A Trunnell, Ramakrishna Meduri, Riaz Shinwari, Mikolaj J Sulkowski, Daniel N Cox   +8 more
doaj   +1 more source

Subtype specific roles of serotonin receptors in the spine formation of cortical neurons in vitro [PDF]

, 2011
Dendritic spines are postsynaptic structures which are formed from filopodia. We examined roles of serotonin (5-HT) receptors in the spine formation. Embryonic rat cortical neurons were cultured for 10 or 14 days and treated by 5-HT receptor agonists for
Kanamaru Chisako, Li Fei, Ohtani Akiko, Senzaki Kouji, Shiga Takashi, Yoshida Hiroyuki, 先崎 浩次, 志賀 隆   +7 more
core   +1 more source

Preferential control of basal dendritic protrusions by EphB2. [PDF]

PLoS ONE, 2011
The flow of information between neurons in many neural circuits is controlled by a highly specialized site of cell-cell contact known as a synapse. A number of molecules have been identified that are involved in central nervous system synapse development,
Matthew S Kayser, Anderson C Lee, Martin Hruska, Matthew B Dalva   +3 more
doaj   +1 more source

Matrix metalloproteinases regulate the formation of dendritic spine head protrusions during chemically induced long-term potentiation. [PDF]

PLoS ONE, 2013
Dendritic spines are are small membranous protrusions that extend from neuronal dendrites and harbor the majority of excitatory synapses. Increasing evidence has shown that matrix metalloproteinases (MMPs), a family of extracellularly acting and Zn(2 ...
Zsuzsanna Szepesi, Monika Bijata, Blazej Ruszczycki, Leszek Kaczmarek, Jakub Wlodarczyk   +4 more
doaj   +1 more source

Differential roles of calcitonin family peptides in the dendrite formation and spinogenesis of the cerebral cortex in vitro [PDF]

, 2011
We examined roles of calcitonin family peptides in the initial stages of dendrite formation and the maturation of dendritic spines in the rat cerebral cortex in vitro.
Harigai Yuichi, Li Fei, Natsume Masaki, Ohtani Akiko, Senzaki Kouji, Shiga Takashi, 先崎 浩次, 志賀 隆   +7 more
core   +1 more source

NESH regulates dendritic spine morphology and synapse formation. [PDF]

PLoS ONE, 2012
BackgroundDendritic spines are small membranous protrusions on the neuronal dendrites that receive synaptic input from axon terminals. Despite their importance for integrating the enormous information flow in the brain, the molecular mechanisms ...
Jeomil Bae, Bong Hwan Sung, In Ha Cho, Seon-Myung Kim, Woo Keun Song   +4 more
doaj   +1 more source