Results 101 to 110 of about 87,585 (230)

Sampling issues in quantitative analysis of dendritic spines morphology

open access: yesBMC Bioinformatics, 2012
Background Quantitative analysis of changes in dendritic spine morphology has become an interesting issue in contemporary neuroscience. However, the diversity in dendritic spine population might seriously influence the result of measurements in which ...
Ruszczycki Błażej   +6 more
doaj   +1 more source

Dendritic Spines [PDF]

open access: yesCurrent Biology, 2002
Zito, Karen, Murthy, Venkatesh N.
openaire   +2 more sources

3D mesh processing using GAMer 2 to enable reaction-diffusion simulations in realistic cellular geometries

open access: yes, 2019
Recent advances in electron microscopy have enabled the imaging of single cells in 3D at nanometer length scale resolutions. An uncharted frontier for in silico biology is the ability to simulate cellular processes using these observed geometries ...
Amaro, Rommie E.   +7 more
core   +1 more source

Monocular deprivation induces dendritic spine elimination in the developing mouse visual cortex

open access: yesScientific Reports, 2017
It is well established that visual deprivation has a profound impact on the responsiveness of neurons in the developing visual cortex. The effect of visual deprivation on synaptic connectivity remains unclear. Using transcranial two-photon microscopy, we
Yanmei Zhou, Baoling Lai, Wen-Biao Gan
doaj   +1 more source

Divergent Roles of p75NTR and Trk Receptors in BDNF's Effects on Dendritic Spine Density and Morphology

open access: yesNeural Plasticity, 2012
Activation of TrkB receptors by brain-derived neurotrophic factor (BDNF) followed by MAPK/ERK signaling increases dendritic spine density and the proportion of mature spines in hippocampal CA1 pyramidal neurons. Considering the opposing actions of p75NTR
Christopher A. Chapleau   +1 more
doaj   +1 more source

EphrinB2 regulates VEGFR2 during dendritogenesis and hippocampal circuitry development

open access: yeseLife, 2019
Vascular endothelial growth factor (VEGF) is an angiogenic factor that play important roles in the nervous system, although it is still unclear which receptors transduce those signals in neurons.
Eva Harde   +8 more
doaj   +1 more source

C. elegans neurons have functional dendritic spines

open access: yeseLife, 2019
Dendritic spines are specialized postsynaptic structures that transduce presynaptic signals, are regulated by neural activity and correlated with learning and memory. Most studies of spine function have focused on the mammalian nervous system.
Andrea Cuentas-Condori   +5 more
doaj   +1 more source

The Effects of Medium Spiny Neuron Morphologcial Changes on Basal Ganglia Network under External Electric Field: A Computational Modeling Study

open access: yesFrontiers in Computational Neuroscience, 2017
The damage of dopaminergic neurons that innervate the striatum has been considered to be the proximate cause of Parkinson's disease (PD). In the dopamine-denervated state, the loss of dendritic spines and the decrease of dendritic length may prevent ...
Xiaohan Zhang   +4 more
doaj   +1 more source

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