Results 81 to 90 of about 591,136 (270)

Dendritic spines are lost in clusters in Alzheimer’s disease [PDF]

, 2021
Mite Mijalkov, Giovanni Volpe, Isabel Fernaud-Espinosa, Javier DeFelipe, Joana B. Pereira, Paula Merino‐Serrais   +5 more
openalex   +1 more source

Molecular Mechanisms Directing Spine Outgrowth and Synaptic Partner Selection in

Journal of Experimental Neuroscience, 2018
The development of the nervous system requires precise outgrowth, extension, and wiring of both axons and dendrites to generate properly functioning neural circuits.
Devyn Oliver, Kellianne Alexander, Michael M Francis   +2 more
doaj   +1 more source

An open-source tool for analysis and automatic identification of dendritic spines using machine learning.

PLoS ONE, 2018
Synaptic plasticity, the cellular basis for learning and memory, is mediated by a complex biochemical network of signaling proteins. These proteins are compartmentalized in dendritic spines, the tiny, bulbous, post-synaptic structures found on neuronal ...
Michael S Smirnov, Tavita R Garrett, Ryohei Yasuda   +2 more
doaj   +1 more source

MicroRNA-9 controls dendritic development by targeting REST [PDF]

, 2014
MicroRNAs (miRNAs) are conserved noncoding RNAs that function as posttranscriptional regulators of gene expression. miR-9 is one of the most abundant miRNAs in the brain.
Akerblom, Akerblom, Ameres, Andres, Aoki, Bak, Ballas, Ballas, Barnes, Bartel, Bonev, Bonhoeffer, Bushati, Caceres, Care, Chen, Chen, Coolen, Coolen, Dajas-Bailador, Delaloy, Dieni, Dotti, Ebert, Edbauer, Feng, Fiore, Gao, Gentner, Giraldez, Goslin, Han, Hand, Haramati, Hering, Hitz, Horch, Jan, Jiang, Jorgensen, Kawabe, Kawauchi, Kluiver, Koch, Kolb, Krichevsky, Kruger, Kuwabara, Laemmli, Lagos-Quintana, Lagos-Quintana, Leucht, Liu, Liu, Liu, London, Loya, Luxenhofer, Ma, Madisen, Magill, Mumm, Nadeau, Olena, Ooi, Otaegi, Packer, Parrish, Parrish, Pathania, Polleux, Qin, Rajan, Refojo, Rodriguez, Saito, Sauvageau, Schoenherr, Schratt, Senyuk, Shibata, Simó, Soriano, Spruston, Sudhof, Takemoto-Kimura, Tronche, Urbanska, Wayman, Whitford, Witkos, Wong, Yamamoto, Yao, Yoo, Zhao   +95 more
core   +1 more source

The malleable brain: plasticity of neural circuits and behavior: A review from students to students [PDF]

, 2017
One of the most intriguing features of the brain is its ability to be malleable, allowing it to adapt continually to changes in the environment. Specific neuronal activity patterns drive long-lasting increases or decreases in the strength of synaptic ...
Adeniyi, Philip A., Ali, Nilufar, Amini, Elham, Blumrich, Eva Maria, Datusalia, Ashok K., Fontanet, Paula, García Romero, Ezra Michelet, Ghosh, Shampa, Golpich, Mojtaba, Hegemann, Regina U., Jain, Vishal, Jamwal, Sumit, Joshi, Pooja, Kushwah, Neetu, Lepeta, Katarzyna, Loke, Hannah, Lourenco, Mychael V., Nawrotek, Katarzyna, Paid, Ramesh K., Pastor, Verónica, Piermartiri, Tetsade, Rotermund, Carola, Saini, Vedangana, Salamian, Ahmad, Schaefer, Natascha, Shahidzadeh, Sheila M., Sharma, Mahima, Sharma, Sorabh, Sinha, Jitendra K., Suárez Pozos, Edna, Turner, Anthony J., Vafadari, Benham, Wilson, Yvette   +32 more
core   +2 more sources

AVNP2 protects against cognitive impairments induced by C6 glioma by suppressing tumour associated inflammation in rats [PDF]

, 2020
© 2020 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/BY-NC-ND/4.0/).Glioblastoma is a kind of malignant tumour and originates from the central nervous system.
Bankier, Barkal, Barria, Benros, Braganhol, Campos-Pires, Chen, Cheong, Chicoine, Crossen, D'Alessandris, d'Isa, da Silva, Dalton, Del Sol-Fernandez, Ferrandon, Froklage, Gong, Graf, Graus, Guogang Ren, Hao, Hara, He, Heppner, Hilverda, Hwang, Jacob, Janelsins, Ji, Jin Gao, Junyang Li, Lang, Liang, Limin Wu, Liu, McFarland, Meicen Liu, Meng, Mineharu, Mostofa, Murata, Myung, Nagano, Nan, Nan, Noy, Oh, Ohgaki, Okada, Ostrom, Ovais, Park, Parrott, Platten, Quant, Reichel, Reid, Ren, Ren, Ren, Saalik, Shan, Sholl, Sim, Solanki, Sorensen, Sorra, Spacek, Stupp, Stupp, Tanaka, Thompson, Thorsson, Van Dyk, Vecht, Venkatesh, Walker, Walker Ii, Wan, Wang, Wang, Weitzner, Williams, Woodward, Wu, Wu, Yang, Yang, Yang, Yang, Yu, Yu Jiang, Yuen-Ki Cheong, Zhang, Zhu, Zhuo Yang, Zong, Zou   +98 more
core   +2 more sources

Barriers in the Brain: Resolving Dendritic Spine Morphology and Compartmentalization

Frontiers in Neuroanatomy, 2014
Dendritic spines are micron-sized protrusions that harbor the majority of excitatory synapses in the central nervous system. The head of the spine is connected to the dendritic shaft by a 50-400 nm thin membrane tube, called the spine neck, which has ...
Max eAdrian, Remy eKusters, Corette J Wierenga, Cornelis eStorm, Casper C Hoogenraad, Lukas C Kapitein   +5 more
doaj   +1 more source

The schizophrenia-associated missense variant rs13107325 regulates dendritic spine density

Translational Psychiatry, 2022
The missense variant rs13107325 (C/T, p.Ala391Thr) in SLC39A8 consistently showed robust association with schizophrenia in recent genome-wide association studies (GWASs), suggesting the potential pathogenicity of this non-synonymous risk variant ...
Shiwu Li, Changguo Ma, Yifan Li, Rui Chen, Yixing Liu, Li Pear Wan, Qiuxia Xiong, Chuang Wang, Yongxia Huo, Xinglun Dang, Yongfeng Yang, Luxian Lv, Xi Chen, Nengyin Sheng, Wenqiang Li, Xiong-Jian Luo   +15 more
doaj   +1 more source

Cocaine-induced structural plasticity in frontal cortex correlates with conditioned place preference. [PDF]

, 2013
Contextual cues associated with previous drug exposure can trigger drug craving and seeking, and form a substantial obstacle in substance use recovery.
Athilingam, Jegath, Muñoz-Cuevas, Francisco Javier, Piscopo, Denise, Wilbrecht, Linda   +3 more
core  

Structural plasticity of dendritic spines [PDF]

Current Opinion in Neurobiology, 2012
Dendritic spines are small mushroom-like protrusions arising from neurons where most excitatory synapses reside. Their peculiar shape suggests that spines can serve as an autonomous postsynaptic compartment that isolates chemical and electrical signaling.
Miquel, Bosch, Yasunori, Hayashi
openaire   +2 more sources