Results 81 to 90 of about 94,485 (200)
Dendritic Spine and Synaptic Plasticity in Alzheimer’s Disease: A Focus on MicroRNA
Frontiers in Cell and Developmental Biology, 2020 Dendrites and dendritic spines are dynamic structures with pivotal roles in brain connectivity and have been recognized as the locus of long-term synaptic plasticity related to cognitive processes such as learning and memory.
Edwin Estefan Reza-Zaldivar +8 more
doaj +1 more source
Maintenance of aversive memories shown by fear extinction-impaired phenotypes is associated with increased activity in the amygdaloid-prefrontal circuit [PDF]
, 2016 Although aversive memory has been mainly addressed by analysing the changes occurring in average populations, the study of neuronal mechanisms of outliers allows understanding the involvement of individual differences in fear conditioning and extinction.
Caioli, Silvia +5 more
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Diffusion laws in dendritic spines [PDF]
The Journal of Mathematical Neuroscience, 2011 Dendritic spines are small protrusions on a neuronal dendrite that are the main locus of excitatory synaptic connections. Although their geometry is variable over time and along the dendrite, they typically consist of a relatively large head connected to the dendritic shaft by a narrow cylindrical neck.
David Holcman, Zeev Schuss
openaire +2 more sources
A joint classification and segmentation approach for dendritic spine segmentation in 2-photon microscopy images [PDF]
, 2014 Shape priors have been successfully used in challenging biomedical imaging problems. However when the shape distribution involves multiple shape classes, leading to a multimodal shape density, effective use of shape priors in segmentation becomes more ...
Argunsah, Ali Ozgur +9 more
core +1 more source
Cell-Type Specific Changes in Glial Morphology and Glucocorticoid Expression During Stress and Aging in the Medial Prefrontal Cortex. [PDF]
, 2018 Repeated exposure to stressors is known to produce large-scale remodeling of neurons within the prefrontal cortex (PFC). Recent work suggests stress-related forms of structural plasticity can interact with aging to drive distinct patterns of pyramidal ...
Bruce S. McEwen +8 more
core +2 more sources
The role of p38 MAPK and its substrates in neuronal plasticity and neurodegenerative disease [PDF]
, 2012 A significant amount of evidence suggests that the p38-mitogen-activated protein kinase (MAPK) signalling cascade plays a crucial role in synaptic plasticity and in neurodegenerative diseases.
Corrêa, Sônia A. L. +1 more
core +3 more sources
Remodeling dendritic spines for treatment of traumatic brain injury
Neural Regeneration Research, 2019 Traumatic brain injury is an important global public health problem. Traumatic brain injury not only causes neural cell death, but also induces dendritic spine degeneration. Spared neurons from cell death in the injured brain may exhibit dendrite damage,
Ye Xiong, Asim Mahmood, Michael Chopp
doaj +1 more source
Protein synthesis at synaptic sites on dendrites [PDF]
, 2001 Studies over the past 20 years have revealed that gene expression in neurons is carried out by a distributed network of translational machinery. One component of this network is localized in dendrites, where polyribosomes and associated membranous ...
Schuman, Erin M., Steward, Oswald
core +1 more source
Journal of Biomedical Science, 2020 Background Dendritic spines, the actin-rich protrusions emerging from dendrites, are the subcellular locations of excitatory synapses in the mammalian brain. Many actin-regulating molecules modulate dendritic spine morphology.
Hsiao-Tang Hu +2 more
doaj +1 more source
Frontiers in NutritionBackgroundObesity is associated with cognitive function impairment. We previously found that male, but not female, mice have poorer performance in learning and memory tasks and impaired hippocampal synaptic plasticity after long-term high-fat diet (HFD ...
Shu-Fang Teng +13 more
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