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Molecular morphogens for dendritic spines
Trends in Neurosciences, 2002 Three protein components of the postsynaptic density--Shank, Homer and SPAR--have been found to regulate the structural and molecular organization of dendritic spines. These new studies reveal linkages between receptor complexes, the actin cytoskeleton and signaling molecules that help shape spines.openaire +2 more sourcesDendritic spines and linear networks
Journal of Physiology-Paris, 2004 The function of the cortical microcircuitry is still mysterious. Using a bottom-up analysis based on the biophysics and connectivity of cortical neurons, we propose the hypothesis that the neocortex is essentially a linear integrator of inputs. Dendritic spines would slow the neuron and contribute to linearize input summation.Rafael, Yuste, Rochelle, Urbanopenaire +2 more sourcesRegulation of dendritic spine stability
Hippocampus, 2000 Dendritic spines undergo several types of transformations, ranging from growth to collapse, and from elongation to shortening, and they experience dynamic morphological activity on a rapid time scale. Changes in spine number and morphology occur under pathological conditions like excitotoxicity, but also during normal central nervous system development,F M, Smart, S, Halpainopenaire +2 more sourcesElectrical Compartmentalization in Dendritic Spines
Annual Review of Neuroscience, 2013 Most excitatory inputs in the CNS contact dendritic spines, avoiding dendritic shafts, so spines must play a key role for neurons. Recent data suggest that, in addition to enhancing connectivity and isolating synaptic biochemistry, spines can behave as electrical compartments independent from their parent dendrites. It is becoming clear that, although openaire +2 more sourcesDendritic Spine
2010 Nicola Simola, Micaela Morelli, Tooru Mizuno, Suzanne H. Mitchell, Harriet de Wit, H. Valerie Curran, Celia J. A. Morgan, Stephan G. Anagnostaras, Jennifer R Sage, Stephanie A Carmack, Lawrence H. Price, Grasielle C Kincheski, Leandro J Bertoglio, Antonio Padua Carobrez, Andrea Bari, Roshan Cools, Yogita Chudasama, Stefan Leucht, Yogita Chudasama, William Breitbart, Yesne Alici, Karl Mann, Falk Kiefer, Yesne Alici, William Breitbart, Michael M Morgan, M J Christie, Istvan Bitter, Eileen M. Joyce, Jonathan P Roiser, Darren R Christensen, Warren K. Bickel, Kenneth J. Rhodes, Peter Paul De Deyn, Debby Van Dam, Darrel J. Pemberton, Johannes Mosbacher, Thomas Steckler, Alyson J Bond, Alex Hofer, Stefan Leucht, Daniel Bertrand, Hans Rollema, Raymond S Hurst, Irwin Lucki, Fadi T. Maalouf, David A. Brent, David A. Brent, Fadi Maalouf, Alex Hofer, Daniel Bertrand, Hans Rollema, Raymond S Hurst, Huaiyu Yang, George I. Papakostas, Andrew Young, Gabriele Fischer, Annemarie Unger, Linda P Spear, Linda P Spear, Mohammed Shoaib, Emma Childs, Britta Hahn, Peter Boeijinga, Martine Cador, David S Tait, Verity J. Brown, Martine Cador, David Baldwin, Yavin Shaham, Sunila G Nair, Yavin Shaham, Sunila G Nair, Matthew I Palmatier, Rick A Bevins, Peter Riederer, Siegfried Hoyer, Mark Geyer, Anthony Absalom, David Menon, Joseph Zohar, Stephen C Fowler, James Winslow, Kim Wolff, Bankole A. Johnson, Martina de Zwaan, Alyson J Bond, Angela Roberts, Anthony R Isles, Lawrence S. Wilkinson, Anthony R Isles, Lawrence S. Wilkinson, Rosa M M de Almeida, Klaus A. Miczek, Eric Nestler, Naheed (Max) Mirza, Bankole A Johnson, Joseph H Friedman, István Bitter, Michael Minzenberg, Lawrence H. Price, Ashwini Padhi, Naomi Fineberg, Michael M Morgan, MacDonald J. Christie, Lawrence H. Price, Joris C. Verster, Bernard Le Foll, Marilyn E Carroll, Peter A Santi, Ronald F Mucha, Ian P. Stolerman, Richard W Foltin, Michael Minzenberg, Christoph Hiemke, Luis Stinus, Stéphanie Caillé, Martine Cador, Yavin Shaham, John R Mantsch, Ronald F Mucha, Kim Wolff, Anthony L. Riley, Steve Kohut, Brian E. Leonard, Joseph Zohar, R. Andrew Chambers, Gail Winger, Mei-Chuan Ko, James H Woods, Huaiyu Yang, George I. Papakostas, Michael M Morgan, MacDonald J. Christie, Seiya Miyamoto, Thomas R. E. Barnes, Kieran O’Malley, Luis Stinus, Stéphanie Caillé, Martine Cador, David J. Hellerstein, Thomas R. E. Barnes +141 moreopenaire +1 more source
