Results 151 to 160 of about 92,267 (298)

Microgravity‐induced changes in skeletal muscle and possible countermeasures: What we can learn from bed rest and human space studies

open access: yesExperimental Physiology, EarlyView.
Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti   +6 more
wiley   +1 more source

Turning over new ideas in human skeletal muscle proteostasis: What do we know and where to from here?

open access: yesExperimental Physiology, EarlyView.
Abstract Understanding the turnover of proteins in tissues gives information as to how external stimuli result in phenotypic change. Nowhere is such phenotypic change more conspicuous than skeletal muscle, which can be effectively remodelled by increased loading, ageing and unloading (disuse), all of which are subject to modification by nutrition and ...
Changhyun Lim   +12 more
wiley   +1 more source

Redox‐regulated signalling of adaptations to contractile activity in skeletal muscle: Implications for age‐related muscle weakness

open access: yesExperimental Physiology, EarlyView.
Abstract Skeletal muscle adaptation to contractile activity is modulated by redox signalling, primarily through reactive oxygen species (ROS) such as hydrogen peroxide (H2O2). Early research framed ROS as deleterious byproducts of exercise, but subsequent studies have established their roles as signalling molecules involved in mitochondrial biogenesis,
Malcolm J. Jackson
wiley   +1 more source

A rare, unusually acute presentation of denervation pseudohypertrophy. [PDF]

open access: yesSAGE Open Med Case Rep
Botross M   +4 more
europepmc   +1 more source

The physiology and biochemistry of total body immobilization in animals: A compendium of research [PDF]

open access: yes
Major studies that describe the physiological and biochemical mechanisms which operate during total body restraint (confinement in cages for example) are presented.
Dorchak, K. J., Greenleaf, J. E.
core   +1 more source

Mitochondrial alterations as potential early events in neuromuscular junction remodelling with muscle disuse

open access: yesExperimental Physiology, EarlyView.
Abstract Physical inactivity impairs neuromuscular health, promoting skeletal muscle atrophy, mitochondrial changes, and neuromuscular junction (NMJ) instability. However, the interplay between mitochondria and NMJ alterations in the context of muscle disuse remains underexplored.
Evgeniia Motanova   +6 more
wiley   +1 more source

Effect of Denervation on Skeletal Muscle Mitochondria in Heterozygous mtDNA Mutator Mice. [PDF]

open access: yesFASEB Bioadv
Shirai T   +6 more
europepmc   +1 more source

Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse

open access: yesExperimental Physiology, EarlyView.
Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley   +1 more source

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