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2016
Sympathetic nervous system over-activity is closely linked with elevation of systemic blood pressure. Both animal and human studies suggest renal sympathetic nerves play an important role in this respect. Historically, modulation of sympathetic activity has been used to treat hypertension. More recently, catheter based renal sympathetic denervation was
Mohammed Awais, Hameed +1 more
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Sympathetic nervous system over-activity is closely linked with elevation of systemic blood pressure. Both animal and human studies suggest renal sympathetic nerves play an important role in this respect. Historically, modulation of sympathetic activity has been used to treat hypertension. More recently, catheter based renal sympathetic denervation was
Mohammed Awais, Hameed +1 more
openaire +2 more sources
BJU International, 2000
The bladder can be denervated at several levels: centrally, at the level of the sacral nerves; peripherally, on the pelvic nerves; or in the bladder, by cutting the relevant structures, by injecting substances toxic to nerves, or by hyperbaric bladder distension. These procedures target the sensory or motor nerves to weaken or to interrupt the detrusor
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The bladder can be denervated at several levels: centrally, at the level of the sacral nerves; peripherally, on the pelvic nerves; or in the bladder, by cutting the relevant structures, by injecting substances toxic to nerves, or by hyperbaric bladder distension. These procedures target the sensory or motor nerves to weaken or to interrupt the detrusor
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Mechanisms of denervation supersensitivity in regionally denervated canine hearts
American Journal of Physiology-Heart and Circulatory Physiology, 1993Mechanisms responsible for “denervation supersensitivity” in regionally denervated canine hearts were examined by measuring beta-adrenergic receptor density and affinity and the density of the alpha-subunit of the stimulatory G protein (Gs alpha). Sympathetic denervation was produced by applying an epicardial strip of phenol midway between the left ...
M R, Warner +4 more
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Denervation-induced alterations of acetylcholinesterase in denervated and nondenervated muscle
Experimental Neurology, 1990The influence of denervation on acetylcholinesterase (AchE) molecular forms in rat skeletal muscle for durations up to 30 days is examined in denervated anterior tibialis, the innervated contralateral muscle, and diaphragm. Denervated rats at a common age of 8.5 weeks are compared with age-matched, nondenervated animals.
M M, Decker, H A, Berman
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Journal of Hand Surgery, 1995
In 1966, Wilhelm published a technique of denervation of the wrist joint based on his own anatomical studies of 1958. Other authors have published their experience in wrist denervations with similar results, but there are some discrepancies in descriptions of the innervation of the wrist.
A, Ferreres +4 more
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In 1966, Wilhelm published a technique of denervation of the wrist joint based on his own anatomical studies of 1958. Other authors have published their experience in wrist denervations with similar results, but there are some discrepancies in descriptions of the innervation of the wrist.
A, Ferreres +4 more
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Pulmonary denervation in the dog
Journal of Applied Physiology, 1983To produce a chronically lung-denervated animal model, a single-stage surgical procedure was performed on five beagle dogs. A left thoracotomy allowed hilar stripping of the pulmonary contributions to the left vagus nerve and transection of the right vagal trunk. The criterion for denervation was defined as the absence of the Hering-Breuer reflex (HBR)
P S, Clifford +4 more
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Bladder Denervation Procedures
Urologic Clinics of North America, 1979Bladder denervation can provide useful rehabilitation of bladder function when other measures have failed. Idiopathic hyperactivity may respond best to hyperbaric distension or bladder transection. Procedures performed close to the bladder seem, at present, to be more effective than those near the central nervous system.
M, Torrens, T, Hald
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Renal Denervation for Hypertension
Current Problems in Cardiology, 2014Hypertension is the leading cause of mortality worldwide. Effective therapies are needed for resistant hypertension, a common condition characterized by inadequate blood pressure control despite 3 or more medications, which is associated with increased cardiovascular mortality.
Mackram F, Eleid +2 more
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Hypertrophy of the Denervated Hemidiaphragm
American Journal of Physiology-Legacy Content, 1956The phenomenon of hypertrophy of the hemidiaphragm following denervation was found to occur in the mouse, rabbit and in the right hemidiaphragm of the rat. The peak of the hypertrophy occurred between 5 and 8 days in the mouse, at which time increases of 24–57% in wet weight of the hemidiaphragm were observed.
A W, MARTIN, D M, STEWART
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Intrapericardial denervation of the heart
Journal of Surgical Research, 1980Abstract A one-stage, low mortality, surgical procedure for complete intrapericardial denervation of the dog heart is described. Examination of chronotropic, inotropic, and dromotropic influences of the autonomic cardiac nerves before and after the operation permits confirmation of the completeness of denervation.
W C, Randall +3 more
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