Results 11 to 20 of about 152,116 (307)

Oligonucleotide-Based Approaches to Inhibit Dengue Virus Replication

Molecules, 2021
Dengue fever is one of the most common viral infections affecting humans. It is an expanding public health problem, particularly in tropical and subtropical regions.
Kingshuk Panda, Kalichamy Alagarasu, Deepti Parashar   +2 more
doaj   +1 more source

Clinical and hepatic evaluation in adult dengue patients: a prospective two-month cohort study

Revista da Sociedade Brasileira de Medicina Tropical, 2012
INTRODUCTION: To analyze the liver dysfunction and evolution of signs and symptoms in adult dengue patients during a two-month follow-up period. METHODS: A prospective cohort study was conducted in Campos dos Goytacazes, Rio de Janeiro, Brazil, from ...
Ricardo Tristão-Sá, Claire Fernandes Kubelka, Eliana Zandonade, Sônia Maria Oliveira Zagne, Natally de Souza Maciel Rocha, Luiza Oliveira Zagne, Nathália Félix Araújo, Beatriz Amin, Flávia Fazoli, Luiz José de Souza, Oswaldo Gonçalves Cruz, Rivaldo Venâncio da Cunha, Delso do Nascimento, Íris Bucher Froes, Rita Maria Ribeiro Nogueira   +14 more
doaj   +1 more source

Role of NS1 antibodies in the pathogenesis of acute secondary dengue infection

Nature Communications, 2018
The antibody response during infection with dengue virus is a key component involved in the pathogenesis during secondary infection. Here the authors show antibodies targeting NS1 and the epitopes targeted can be associated with disease severity during ...
Deshni Jayathilaka, Laksiri Gomes, Chandima Jeewandara, Geethal. S. Bandara Jayarathna, Dhanushka Herath, Pathum Asela Perera, Samitha Fernando, Ananda Wijewickrama, Clare S. Hardman, Graham S. Ogg, Gathsaurie Neelika Malavige   +10 more
doaj   +1 more source

DIFFERENCES OF UNIVERSAL AND MULTIPLEX PRIMER FOR DETECTION OF DENGUE VIRUS FROM PATIENTS SUSPECTED DENGUE HEMORRHAGIC FEVER (DHF) IN SURABAYA

Indonesian Journal of Tropical and Infectious Disease, 2015
Dengue Hemorrhagic Fever (DHF) is a global health problem in tropical and subtropical regions, as well as endemic in110 countries around the world. Indonesia is one of the largest countries in the region of endemic dengue.
Arif Ansori, Teguh Sucipto, Pemta Deka, Nur Ahwanah, Siti Churrotin, Tomohiro Kotaki, Soegeng Soegijanto   +6 more
doaj   +1 more source

Seroprevalence and incidence of primary dengue infections among children in a rural region of Maharashtra, Western India

BMC Infectious Diseases, 2019
Background Dengue infections have become a huge threat to public health systems in developing countries. Data on seroprevalence and incidence of dengue infections are lacking from rural regions of India.
Paresh S. Shah, Kalichamy Alagarasu, Shivaji Karad, Avinash Deoshatwar, Santosh M. Jadhav, Tushar Raut, Anand Singh, Cecilia Dayaraj, Vasant S. Padbidri   +8 more
doaj   +1 more source

SARS-CoV-2 neutralizing antibodies in patients with varying severity of acute COVID-19 illness

Scientific Reports, 2021
In order to support vaccine development, and to aid convalescent plasma therapy, it would be important to understand the kinetics, timing and persistence of SARS-CoV-2 neutralizing antibodies (NAbs), and their association with clinical disease severity ...
Chandima Jeewandara, Deshni Jayathilaka, Laksiri Gomes, Ananda Wijewickrama, Eranga Narangoda, Damayanthi Idampitiya, Dinuka Guruge, Ruwan Wijayamuni, Suranga Manilgama, Graham S. Ogg, Chee Wah Tan, Lin-Fa Wang, Gathsaurie Neelika Malavige   +12 more
doaj   +1 more source

Drug repurposing approach against chikungunya virus: an in vitro and in silico study

Frontiers in Cellular and Infection Microbiology, 2023
The chikungunya virus (CHIKV) is an alphavirus transmitted by Aedes mosquitoes. There are no licenced antivirals or vaccines for treatment or prevention. Drug repurposing approach has emerged as a novel concept to find alternative uses of therapeutics to
Bhagyashri Kasabe, Gunwant Ahire, Poonam Patil, Madhura Punekar, Kusuma Sai Davuluri, Mahadeo Kakade, Kalichamy Alagarasu, Deepti Parashar, Sarah Cherian   +8 more
doaj   +1 more source

Hemorrhagic encephalopathy in dengue shock syndrome: a case report

Brazilian Journal of Infectious Diseases
Dengue fever is the most important arboviral infection in the world, with an estimated 100 million cases per year and 2.5 billion people at risk.
Luiz José de Souza, André Luiz de Oliveira Martins, Paulo César Leitão Paravidini, Rita Maria Ribeiro Nogueira, Carlos Gicovate Neto, Diogo Assed Bastos, Edno Wallace da Silva Siqueira, Rodrigo da Costa Carneiro   +7 more
doaj   +1 more source

The impact of dengue on liver function as evaluated by aminotransferase levels

Brazilian Journal of Infectious Diseases
The objective of this study was to evaluate the impact of dengue virus infection on liver function by measuring aminotransferase in blood samples from patients serologically diagnosed by according to two MAC-ELISA protocols.
Luiz José de Souza, Rita Maria Ribeiro Nogueira, Leandro Cordeiro Soares, Carlos Eduardo Cordeiro Soares, Bruno Fernandes Ribas, Felipe Pinto Alves, Fabíola Rodrigues Vieira, Felipe Eulálio Baldi Pessanha   +7 more
doaj   +1 more source

Identification of Novel Candidate CD8⁺ T Cell Epitopes of the SARS-CoV2 with Homology to Other Seasonal Coronaviruses

Viruses, 2021
Cross-reactive T cell immunity to seasonal coronaviruses (HCoVs) may lead to immunopathology or protection during SARS-CoV2 infection. To understand the influence of cross-reactive T cell responses, we used IEDB (Immune epitope database) and NetMHCpan ...
Pradeep Darshana Pushpakumara, Deshan Madhusanka, Saubhagya Dhanasekara, Chandima Jeewandara, Graham S. Ogg, Gathsaurie Neelika Malavige   +5 more
doaj   +1 more source