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British Medical Bulletin, 2010 Dengue is a vector-borne viral infection that endangers an estimated 2.5 billion people. Disease caused by dengue ranges from a relatively minor febrile illness to a life-threatening condition characterized by extensive capillary leak. A greater understanding of dengue has the potential to improve both the clinical management of individual cases and ...
Whitehorn, J, Farrar, J
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Dengue and Dengue Hemorrhagic Fever [PDF]
Clinical Microbiology Reviews, 1997 SUMMARYDengue fever, a very old disease, has reemerged in the past 20 years with an expanded geographic distribution of both the viruses and the mosquito vectors, increased epidemic activity, the development of hyperendemicity (the cocirculation of multiple serotypes), and the emergence of dengue hemorrhagic fever in new geographic regions.
Edward B. Hayes, Duane J. Gubler
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Dengue and dengue haemorrhagic fever [PDF]
The Lancet, 1998 The incidence and geographical distribution of dengue have greatly increased in recent years. Dengue is an acute mosquito-transmitted viral disease characterised by fever, headache, muscle and joint pains, rash, nausea, and vomiting. Some infections result in dengue haemorrhagic fever (DHF), a syndrome that in its most severe form can threaten the ...
Rigau-Pérez, J +5 more
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New England Journal of Medicine, 2012 Dengue is a self-limited, systemic viral infection transmitted between humans by mosquitoes. The rapidly expanding global footprint of dengue is a public health challenge with an economic burden that is currently unmet by licensed vaccines, specific therapeutic agents, or efficient vectorcontrol strategies.
Simmons, CP +3 more
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Canadian Medical Association JournalThis JAMA Insights explores several aspects of dengue virus infection, including epidemiology, diagnosis, and clinical management, following a global resurgence in both endemic and nonendemic regions.
Billick, Maxime J., Bogoch, Isaac I.
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Acta Médica Costarricense, 2008 El dengue sigue siendo la arbovirosis humana más importante. Según estimaciones 2,500 a 3,000 millones de personas viven en áreas de riesgo de transmisión; al año ocurren 50 millones de infecciones, de las cuales 500 mil son dengue hemorrágico (DH), 21,000 morirán, la gran mayoría niños. El cambio climático, la alteración de los ecosistemas (cambios en
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The pathogenesis of dengue [PDF]
Vaccine, 2011 Dengue is an important cause of childhood and adult morbidity in Asian and Latin American countries and its geographic footprint is growing. The clinical manifestations of dengue are the expression of a constellation of host and viral factors, some acquired, others intrinsic to the individual.
Whitehorn, J, Simmons, CP
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Phenotype and functionality of follicular helper T cells in patients with acute dengue infection
Journal of Biomedical Science, 2020 Background The association of functionality and phenotype of follicular helper T cells (Tfh) with dengue virus (DENV) specific antibody responses and clinical disease severity has not been well studied.
Ayesha Wijesinghe +10 more
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Seroprevalence of dengue virus infection in Pune City in India, 2019: A decadal change
Journal of Infection and Public Health, 2023 Background: The burden of dengue infection needs to be monitored along with tracking of the changes in dengue virus (DENV) transmission intensity for vaccine introduction decisions.
Kalichamy Alagarasu +9 more
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Viruses, 2020 Dengue, caused by infection of any of four dengue virus serotypes (DENV-1 to DENV-4), is a mosquito-borne disease of major public health concern associated with significant morbidity, mortality, and economic cost, particularly in developing countries. Dengue incidence has increased 30-fold in the last 50 years and over 50% of the world’s population, in
Harapan Harapan +3 more
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