Results 91 to 100 of about 84,432 (239)

Tenofovir disoproxil fumarate induces peripheral neuropathy and alters inflammation and mitochondrial biogenesis in the brains of mice. [PDF]

open access: yes, 2019
Mounting evidence suggests that antiretroviral therapy (ART) drugs may contribute to the prevalence of HIV-associated neurological dysfunction. The HIV envelope glycoprotein (gp120) is neurotoxic and has been linked to alterations in mitochondrial ...
Achim, Cristian L   +11 more
core  

Effect of Nutraceutical Supplementation and Mediterranean Hypocaloric Diet on Calculated Steatosis Indices and Inflammation: Clinical and In Vitro Evidences

open access: yesMolecular Nutrition &Food Research, EarlyView.
This retrospective study evaluated the effects of nutraceutical supplementation (NS) and a Mediterranean hypocaloric diet (MHD) in NAFLD patients. Forty‐five overweight/obese subjects followed MHD with or without NS. After 3 months, only the MHD + NS group showed significant improvements in liver steatosis indices and inflammation.
Mariana Di Lorenzo   +11 more
wiley   +1 more source

Rutin Enhances Intestinal Barrier Function and Protects Against X‐Ray Radiation‐Induced Barrier Dysfunction in Human Epithelial Caco‐2 Cells

open access: yesMolecular Nutrition &Food Research, EarlyView.
Rutin enhances intestinal epithelial barrier function by upregulating TJ‐related proteins (ZO‐2, occludin, and claudin‐3), reducing paracellular permeability, and restoring Caco‐2 cell viability impaired by X‐ray radiation. These effects suggest rutin's potential as a natural radioprotective agent for maintaining intestinal barrier integrity under ...
Ha‐Young Park   +3 more
wiley   +1 more source

Method for Accurately Assessing the Impact of Enzyme Encapsulation in a Protein Nanocage

open access: yesNano Select, EarlyView.
We have developed methods for both encapsulating a thermostable enzyme within the artificial protein nanocage TIP60 and releasing it by heating. This enables a direct comparison of the activity of confined and free enzymes under identical reaction conditions, providing a more accurate assessment of how encapsulation affects enzymatic activity ...
Norifumi Kawakami   +5 more
wiley   +1 more source

Changes in zebrafish (Danio rerio) lens crystallin content during development. [PDF]

open access: yes, 2013
PurposeThe roles that crystallin proteins play during lens development are not well understood. Similarities in the adult crystallin composition of mammalian and zebrafish lenses have made the latter a valuable model for examining lens function.
Corbin, Rebecca W   +4 more
core   +1 more source

Insights into the mechanism of reversible blood‐brain barrier opening via second near‐infrared region excited gold nanorods photothermal effect: Regulation of the tight junction protein occludin

open access: yesSmart Molecules, EarlyView.
The photothermal effect generated by second near‐infrared (NIR‐II) laser‐activated gold nanorods (AuNRs) enables reversible blood‐brain barrier (BBB) opening, temporarily increasing its permeability. This process involves the downregulation of tight junction proteins, such as occludin, and triggers their conformational changes.
Kaili Liang   +8 more
wiley   +1 more source

Biomass production of tropical trees across space and time: The shifting roles of diameter growth and wood density

open access: yesJournal of Ecology, EarlyView.
Diameter growth is an important and good indicator of forest carbon production. However, size‐related changes in wood density, which are usually neglected, are critical for accurate short‐ and long‐term carbon assessments, especially in tropical humid sites.
Bruna Hornink   +18 more
wiley   +1 more source

Transgender and Gender Diverse Patient Experiences, Care and Health Outcomes in Medical Imaging: A Scoping Review

open access: yesJournal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Background Changes in legislation and social attitudes towards transgender and gender diverse (TGD) people have prompted clinical and ethical questions about the experiences, care, and health outcomes of TGD patients in medical imaging. Aim The aim of this scoping review is to identify the main themes surrounding TGD patient care in medical ...
Kirralee Jane Davies, Ricky Lam
wiley   +1 more source

Home - About - Disclaimer - Privacy