Results 91 to 100 of about 149,082 (291)

Hydroxyl Groups on the B Ring of Flavonols Significantly Impact the Energy and Lipid Metabolism in Mice: A Biochemical and Gut Microbiota Approach

open access: yesFood Chemistry International, EarlyView.
The number and position of hydroxyl groups on the B ring of flavonols led to differences in regulating energy metabolism in mice. ABSTRACT In this study, quercetin, myricetin, kaempferol, and morin were compared in context to their ameliorative effects on lipid disorders in high‐fat dietary mice.
Weizhi Zhong   +4 more
wiley   +1 more source

Effect of Teriparatide in Postmenopausal Women with Osteoporosis

open access: yesJournal of Mazandaran University of Medical Sciences, 2018
Background and purpose: Osteoporosis is the most common metabolic bone disease. The aim of this study was to evaluate the effects of teriparatide on the incidence of fractures and bone density in postmenopausal women with osteoporosis.
Masoud Shayestehazar   +5 more
doaj  

Kaempferitrin's Dual Assault: Inducing Apoptosis and Ferroptosis in Diffuse Large B‐Cell Lymphoma via NF‐κB Inactivation

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) is the most common non‐Hodgkin lymphoma and is an aggressive and highly heterogeneous tumor. Kaempferitrin (KPF) is a natural flavonoid glycoside that exerts a protective role in multiple human tumors. However, the impact of KPF on DLBCL remains unclear.
Han‐Shuo Zhang   +3 more
wiley   +1 more source

Loganin, an Iridoid Glycoside, Alleviates Paclitaxel‐Induced Skeletal Muscle Toxicity by Enhancing Mitochondrial Function, Boosting Antioxidant Defenses, and Reducing Cellular Senescence

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Mitochondrial dysfunction and energy imbalance caused by chemotherapy are key contributors to skeletal muscle atrophy, which severely impacts the quality of life in cancer patients. Paclitaxel, a commonly used chemotherapeutic agent, is known to promote muscle wasting and cellular senescence, largely by impairing mitochondrial function.
Yu‐Fan Chuang   +6 more
wiley   +1 more source

Effect of Nutraceutical Supplementation and Mediterranean Hypocaloric Diet on Calculated Steatosis Indices and Inflammation: Clinical and In Vitro Evidences

open access: yesMolecular Nutrition &Food Research, EarlyView.
This retrospective study evaluated the effects of nutraceutical supplementation (NS) and a Mediterranean hypocaloric diet (MHD) in NAFLD patients. Forty‐five overweight/obese subjects followed MHD with or without NS. After 3 months, only the MHD + NS group showed significant improvements in liver steatosis indices and inflammation.
Mariana Di Lorenzo   +11 more
wiley   +1 more source

Rutin Enhances Intestinal Barrier Function and Protects Against X‐Ray Radiation‐Induced Barrier Dysfunction in Human Epithelial Caco‐2 Cells

open access: yesMolecular Nutrition &Food Research, EarlyView.
Rutin enhances intestinal epithelial barrier function by upregulating TJ‐related proteins (ZO‐2, occludin, and claudin‐3), reducing paracellular permeability, and restoring Caco‐2 cell viability impaired by X‐ray radiation. These effects suggest rutin's potential as a natural radioprotective agent for maintaining intestinal barrier integrity under ...
Ha‐Young Park   +3 more
wiley   +1 more source

Bone Health Following Lifestyle‐Induced Weight Loss in Individuals With Overweight/Obesity: A Narrative Review

open access: yesObesity, EarlyView.
ABSTRACT Although weight loss has many health benefits for people with overweight/obesity, its potential negative impact on bone health needs to be considered. This review provides a comprehensive overview of the effects of intentional weight loss achieved by lifestyle changes on bone health outcomes in adults with overweight/obesity and discusses ...
Mélanie A. Legrand   +7 more
wiley   +1 more source

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