Results 61 to 70 of about 224,534 (289)

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Utilization of bone densitometry for prediction and administration of bisphosphonates to prevent osteoporosis in patients with prostate cancer without bone metastases receiving antiandrogen therapy

Cancer Management and Research, 2014
Abby Holt,1 Muhammad A Khan,2 Swetha Gujja,3 Rangaswmy Govindarajan31Arkansas Department of Health, Little Rock, 2White River Health System, Batesville, 3Division of Hematology/Oncology, University of Arkansas for Medical Sciences, Little Rock, AR ...
Holt A, Khan MA, Gujja S, Govindarajan R
doaj  

Measuring of Mandible Bone Density in Dogs Using /Digital Radiography/ Radiovisigraphy

Acta Veterinaria, 2020
Radiological diagnostics serves as one of the basic monitoring techniques in veterinary dental practice. The recent up-to-date literature data based on the findings of digital radiology/radiovisiography (RVG) in general dentistry inspired the authors to ...
Ilić Dragan, Stojanović Ljiljana, Antonijević Djordje, Milutinović-Smiljanić Sanja, Savić-Stanković Tatjana, Milosavljević Željko   +5 more
doaj   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

ASSESSMENT OF BONE MINERAL DENSITY IN PATIENTS WITH HODGKIN’S LYMPHOMA

Сибирский научный медицинский журнал, 2019
Currently, Hodgkin’s lymphoma (HL) is considered as a potentially curable disease. The polychemotherapy including various combinations of cytostatic drugs and glucocorticoids appears the standard of treatment in patients with HL.
M. S. Voytko, T. I. Pospelova, V. V. Klimontov, O. N. Fazullina, E. V. Mezit   +4 more
doaj   +1 more source

Densitometry and Thermometry of Starburst Galaxies

, 2011
With a goal toward deriving the physical conditions in external galaxies, we present a survey of formaldehyde (H2CO) and ammonia (NH3) emission and absorption in a sample of starburst galaxies using the Green Bank Telescope. By extending well-established
Araya, Baan, Baan, Baan, C. Henkel, Henkel, J. Darling, J.G. Mangum, K.M. Menten, M. MacGregor, Mangum, Morris, Ott, Young   +13 more
core   +1 more source

Estrogens promote misfolded proinsulin degradation to protect insulin production and delay diabetes [PDF]

, 2018
Summary: Conjugated estrogens (CE) delay the onset of type 2 diabetes (T2D) in postmenopausal women, but the mechanism is unclear. In T2D, the endoplasmic reticulum (ER) fails to promote proinsulin folding and, in failing to do so, promotes ER stress and
Allard, Camille, Alvarez-Mercado, Ana I, Arvan, Peter, Coons, Laurel A, Floyd, Z. Elizabeth, Fuselier, Taylor, Hewitt, Sylvia C, Kim, Jun Ho, Korach, Kenneth S, Levin, Ellis R, Mauvais-Jarvis, Franck, Urano, Fumihiko, Xu, Beibei   +12 more
core   +2 more sources

Astrocyte‐Guided Maturation of Neural Constructs in a Modular Biosynthetic Hydrogel for Biohybrid Neurotechnologies

Advanced Functional Materials, EarlyView.
A modular biosynthetic PVA–gelatin hydrogel crosslinked via visible‐light thiol‐ene chemistry is engineered as a coating for neural electrodes. Optimizing matrix composition and mechanical properties enables the hydrogel to support astrocytic populations that guide neural differentiation and functional maturation.
Martina Genta, Sofia Peressotti, Roberto Portillo‐Lara, Josef Goding, Rylie Green   +4 more
wiley   +1 more source

Investigation of How Corneal Densitometry Artefacts Affect the Imaging of Normal and Keratoconic Corneas

Bioengineering
Purpose: To investigate corneal densitometry artefacts found in Pentacam Scheimpflug scans and their potential effect on assessing keratoconic (KC) corneas compared to normal (N) corneas.
Rami Alanazi, Louise Pellegrino Gomes Esporcatte, Lynn White, Marcella Q. Salomão, Bernardo T. Lopes, Renato Ambrósio Jr., Ahmed Abass   +6 more
doaj   +1 more source

Automatic Quantification of Interstitial Lung Disease From Chest Computed Tomography in Systemic Sclerosis

Frontiers in Medicine, 2020
Background: Interstitial lung disease (ILD) is a common complication in patients with systemic sclerosis (SSc), and its diagnosis contributes to early treatment decisions.Purposes: To quantify ILD associated with SSc (SSc-ILD) from chest CT images using ...
Alysson Roncally S. Carvalho, Alysson Roncally S. Carvalho, Alysson Roncally S. Carvalho, Alan R. Guimarães, Flávio R. Sztajnbok, Rosana Souza Rodrigues, Rosana Souza Rodrigues, Bruno Rangel Antunes Silva, Agnaldo José Lopes, Walter Araujo Zin, Isabel Almeida, Manuela Maria França   +11 more
doaj   +1 more source