Results 131 to 140 of about 60,070 (305)

Space biomedicine‐oriented bioink and biomimetic blood‒brain barrier

VIEW, EarlyView.
Bioinks and bioprinting play a pivotal role in the successful delivery of cell models and the fabrication of tissue models for space biomedicine research. This study investigated the effects of hypergravity and vibration on two‐dimensional adherent cells and three‐dimensional embedded cells and provided methods for storing hybrid bioink and high ...
Ranran Yan, Ge Gao, YuJuan Li, YuLin Deng   +3 more
wiley   +1 more source

A modified efficient method for dental pulp stem cell isolation

Dental Research Journal, 2014
Background: Dental pulp stem cells can be used in regenerative endodontic therapy. The aim of this study was to introduce an efficient method for dental pulp stem cells isolation.
Maryam Raoof, Mohammad Mehdi Yaghoobi, Ali Derakhshani, Ali Mohammadi Kamal-abadi, Behnam Ebrahimi, Mehdi Abbasnejad, Noushin Shokouhinejad   +6 more
doaj  

Harnessing energy metabolism for enhanced bone defect repair: Mechanisms and therapeutic strategies

VIEW, EarlyView.
This review addresses the critical challenge of bone defect repair by focusing on the underexplored role of cellular energy metabolism. It synthesizes regulatory mechanisms in bone‐forming cells and sums up innovative strategies—leveraging cell derivatives, active factors, and biomimetic scaffolds—to modulate metabolism for enhanced regeneration.
Junting Li, Yulan Liu, Yuran Li, Yingjie Hua, Xinquan Jiang, Mingliang Zhou   +5 more
wiley   +1 more source

Angiogenic regulation of dental pulp stem cells

Frontiers in Dental Medicine
Tissue regeneration relies on the ingrowth of blood vessels from the host for the survival and functionalization of regenerated tissues. Any holdup in this process can threaten the viability of the transplanted progenitor cells, which in turn can hinder effective tissue regeneration.
Dissanayaka, Waruna Lakmal, Nowwarote, Nunthawan, Srisuwan, Tanida, Hiran-Us, Sirawut, Kornsuthisopon, Chatvadee, Zhu, Xiaofei, Osathanon, Thanaphum   +6 more
openaire   +2 more sources

How Well Are Dental Students Equipped to Handle Traumatic Dental Injuries in Children?

Australian Endodontic Journal, EarlyView.
ABSTRACT To evaluate dental students' knowledge and confidence in managing dental trauma (TDI). An observational questionnaire‐based study involving fourth‐year BDSc (Hons) students from 2022 and 2023 at UQ, following their Traumatic Dental Injury module.
Sobia Zafar, Luan Lin Jovita Cheong, Vonn Ler, Anastasia Min Teh, Paul Abbott   +4 more
wiley   +1 more source

Dental Pulp Stem Cells: Advances to Applications.

Stem cells and cloning : advances and applications, 2020
Dental pulp stem cells (DPSCs) have a high capacity for differentiation and the ability to regenerate a dentin/pulp-like complex. Numerous studies have provided evidence of DPSCs' differentiation capacity, such as in neurogenesis, adipogenesis, osteogenesis, chondrogenesis, angiogenesis, and dentinogenesis.
openaire   +3 more sources

Hypoxia Exacerbates Periapical Periodontitis‐Associated Pathological Bone Loss via the Hypoxia‐Inducible Factor‐2α‐Calmodulin‐Dependent Protein Kinase IV Axis

Cell Proliferation, EarlyView.
Hypoxia exposure activates HIF‐2α, which binds to the Camk4 promoter to enhance RANKL‐mediated osteoclast differentiation, leading to aggravated alveolar bone resorption in periapical periodontitis. ABSTRACT Periapical periodontitis is one of the most common inflammatory bone destructive diseases. Epidemiological evidence suggests that hypoxia exposure,
Kang Gao, Yifan Xu, Haoran Du, Zixiao Li, Xiaochen Fang, Minghui Wang, Jia Liu, Xu Zha, Xianglong Han, Weihua Guo, Xicheng Liu, Jian Zhou   +11 more
wiley   +1 more source

Dental Pulp Stem Cell–Derived Multicellular Microtissue Spheres: A Synergistic Strategy for Dental Pulp Regeneration

International Dental Journal
Objective: Restoring pulp tissue to its natural state is the ultimate goal of pulp regeneration, during which vascularization and neuralization of regenerated pulp are key factors.
Wei Jian, Fang Ma, Ying Xian, Xingyan Shi, Hairong Ma, Shenglan Ma, Ling Qin, Rui Zhang, Hualin Zhang   +8 more
doaj   +1 more source

A review of the methods used to study biocompatibility of Portland cement-derived materials used in dentistry [PDF]

, 2006
Advanced restorative dentistry may necessitate the need for surgical intervention to the infected root apex. Once access to the root end is achieved, the root apex is resected and filled with a dental restorative material.
Camilleri, Josette
core  

Single‐Cell Virtual Perturbation Screening Identifies STAT3 as a Key Regulator of Dentinogenesis

Cell Proliferation, EarlyView.
STAT3 promotes odontoblast differentiation in dental mesenchymal cells by transcriptionally regulating WNT2B via the canonical Wnt/β‐catenin signalling pathway. These findings elucidate a mechanism underlying dentine development. ABSTRACT Dentine formation constitutes a physiological process precisely regulated by signal transduction modules governing ...
Yanfei Zhu, Hongyuan Xu, Zijian Zhang, Siyuan Sun, Zihan Huang, Xin Gao, Houwen Pan, Xiangru Huang, Yuanqi Liu, Xinyu Wang, Hanbin Jia, Qinggang Dai, Lingyong Jiang   +12 more
wiley   +1 more source