Results 251 to 260 of about 59,254 (304)

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

open access: yesAdvanced Science, Volume 13, Issue 8, 9 February 2026.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha   +12 more
wiley   +1 more source

Elevator‐Like Hollow Channels in Porous Scaffolds Accelerate Vascularized Bone Regeneration via NETs‐Fibrin‐Mediated Macrophage Recruitment

open access: yesAdvanced Science, Volume 13, Issue 9, 13 February 2026.
This study demonstrates that how hollow‐channel scaffolds promote vascularized bone regeneration via an immunomodulatory mechanism. The channel structures facilitate the formation of a neutrophil extracellular traps‐fibrin scaffold that recruits vascular endothelial growth factor A (VEGF‐A)‐secreting M2 macrophages to drive angiogenesis. Combining this
Guifang Wang   +8 more
wiley   +1 more source

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis (Adv. Sci. 8/2026)

open access: yesAdvanced Science, Volume 13, Issue 8, 9 February 2026.
Human Atlas of Tooth Decay Progression This cover presents a high‐resolution volumetric image of the vasculature within a healthy human dental pulp. This 3D reconstruction reveals the remarkable complexity and beauty of the pulp's microvascular tree, captured through advanced clearing and imaging approaches. The result is an extraordinary visualization
Hoang Thai Ha   +12 more
wiley   +1 more source

Hierarchical Self‐Assembled Nanoparticles for Efficient and Eco‐Friendly Herbicide Delivery

open access: yesAggregate, Volume 7, Issue 2, February 2026.
Hierarchical host–guest and electrostatic self‐assembly of Diuron/SBE‐β‐CD@CSH for enhanced herbicide efficacy and environmentally safe delivery. ABSTRACT Herbicides are indispensable for safeguarding global crop production, yet their effectiveness is often undermined by extensive environmental losses during application.
Yuntian Xiao   +6 more
wiley   +1 more source

Synergistic Antifungal Effects of Honokiol and Fluconazole Against Oral Candida: Implications for Managing Drug‐Resistant Infections

open access: yesClinical and Experimental Dental Research, Volume 12, Issue 1, February 2026.
ABSTRACT Objectives Antifungal drug resistance poses a major challenge in treating oral Candida infections. This study aimed to evaluate the antifungal activity of Honokiol, alone and combined with Fluconazole, against oral Candida isolates, and to investigate its mechanism of action via ergosterol biosynthesis inhibition and cell wall disruption ...
Maribasappa Karched   +2 more
wiley   +1 more source

Impact of Various Sleeve Materials on Temperature Variations During Guided Endodontic Access Cavity Preparation Utilizing Finite‐Element Analysis

open access: yesClinical and Experimental Dental Research, Volume 12, Issue 1, February 2026.
ABSTRACT Purpose Guided endodontics allows precise access in challenging cases such as calcified canals; however, drilling can generate temperature increases that risk damaging periradicular tissues. This study aimed to evaluate the influence of different sleeve materials—zirconia, cobalt‐chromium (CoCr), and titanium—on temperature changes during ...
Anna Muryani   +5 more
wiley   +1 more source

Dental Pulp Stem Cell Migration

Journal of Endodontics, 2010
The purpose of this in vitro study was to investigate the migration of dental pulp stem cells (DPSCs) in response to chemotactants and extracellular matrix proteins (EMPs). This DPSC signaling information is needed to help understand tooth regeneration after injury and to develop some future regenerative endodontic therapies.DPSCs were released by ...
Cameron, Howard   +2 more
openaire   +2 more sources

Dental Pulp Stem Cells

2006
Postnatal stem cells have been isolated from a variety of tissues. These stem cells are thought to possess great therapeutic potential for repairing damaged and/or defective tissues. Clinically, hematopoietic stem cells have been successfully used for decades in the treatment of various diseases and disorders.
Liu, H., Gronthos, S., Shi, S.
openaire   +3 more sources

Human dental pulp stem cells and hormesis

Ageing Research Reviews, 2022
This paper represents the first assessment of hormetic dose responses by human dental pulp stem cells (hDPSCs) with particular emphasis on cell renewal (proliferation) and differentiation. Hormetic dose responses were commonly reported in this model, encompassing a broad range of chemicals, including principally pharmaceuticals (e.g., metformin and ...
Calabrese, Edward J   +4 more
openaire   +3 more sources

Primary Culture of Dental Pulp Stem Cells

Journal of Visualized Experiments, 2023
The human dental pulp represents a promising multipotent stem cell reservoir with pre-eminent regenerative competence that can be harvested from an extracted tooth. The neural crest-derived ecto-mesenchymal origin of dental pulp stem cells (DPSCs) bestows a high degree of plasticity that owes to its multifaceted benefits in tissue repair and ...
Ajay, Kumar   +4 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy