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Dental stem cell and dental tissue regeneration
Frontiers of Medicine, 2018The teeth are highly differentiated chewing organs formed by the development of tooth germ tissue located in the jaw and consist of the enamel, dentin, cementum, pulp, and periodontal tissue. Moreover, the teeth have a complicated regulatory mechanism, special histologic origin, diverse structure, and important function in mastication, articulation ...
Qiming, Zhai +4 more
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2006
Postnatal stem cells have been isolated from a variety of tissues. These stem cells are thought to possess great therapeutic potential for repairing damaged and/or defective tissues. Clinically, hematopoietic stem cells have been successfully used for decades in the treatment of various diseases and disorders.
Liu, H., Gronthos, S., Shi, S.
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Postnatal stem cells have been isolated from a variety of tissues. These stem cells are thought to possess great therapeutic potential for repairing damaged and/or defective tissues. Clinically, hematopoietic stem cells have been successfully used for decades in the treatment of various diseases and disorders.
Liu, H., Gronthos, S., Shi, S.
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Stem Cell Properties of Human Dental Pulp Stem Cells
Journal of Dental Research, 2002In this study, we characterized the self-renewal capability, multi-lineage differentiation capacity, and clonogenic efficiency of human dental pulp stem cells (DPSCs). DPSCs were capable of forming ectopic dentin and associated pulp tissue in vivo. Stromal-like cells were reestablished in culture from primary DPSC transplants and re-transplanted into ...
S, Gronthos +8 more
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Dental Pulp Stem Cell Migration
Journal of Endodontics, 2010The purpose of this in vitro study was to investigate the migration of dental pulp stem cells (DPSCs) in response to chemotactants and extracellular matrix proteins (EMPs). This DPSC signaling information is needed to help understand tooth regeneration after injury and to develop some future regenerative endodontic therapies.DPSCs were released by ...
Cameron, Howard +2 more
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Regeneration of Dental Pulp by Stem Cells
Advances in Dental Research, 2011Angiogenesis/vasculogenesis and neurogenesis are essential for pulp regeneration. Two subfractions of side-population (SP) cells, CD31-/CD146- SP cells and CD105+ cells with angiogenic and neurogenic potential, were isolated by flow cytometry from canine dental pulp.
M, Nakashima, K, Iohara
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Dental Pulp Stem Cells and Neurogenesis
2017Recent advances in regenerative medicine and cell-based therapy are bringing promising perspectives for the use of stem cells in clinical trials. Stem cells are undifferentiated cells capable of multilineage differentiation and available in numerous sources in the human body.
Ibrahim, Mortada +2 more
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Current Stem Cell Research & Therapy, 2014
Stem cell-based therapies are considered as a promising treatment for many clinical usage such as tooth regeneration, bone repairation, spinal cord injury, and so on. However, the ideal stem cell for stem cell-based therapy still remains to be elucidated.
Jiali, Tan +5 more
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Stem cell-based therapies are considered as a promising treatment for many clinical usage such as tooth regeneration, bone repairation, spinal cord injury, and so on. However, the ideal stem cell for stem cell-based therapy still remains to be elucidated.
Jiali, Tan +5 more
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2020
Recently, tooth tissue engineering has attracted more and more attention. Teeth exhibit limited repair in response to damage, and dental pulp stem cells provide a source of cells to replace those damaged and to facilitate repair. Mesenchymal stem cells (MSCs) are multipotent stem cells which can be differentiated into a variety of cell types.
ÇAĞLAYAN, Anıl, ELBE, Hülya
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Recently, tooth tissue engineering has attracted more and more attention. Teeth exhibit limited repair in response to damage, and dental pulp stem cells provide a source of cells to replace those damaged and to facilitate repair. Mesenchymal stem cells (MSCs) are multipotent stem cells which can be differentiated into a variety of cell types.
ÇAĞLAYAN, Anıl, ELBE, Hülya
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Dental Stem Cells and Tooth Regeneration
2018Dental stem cells are a minor population of mesenchymal stem cells existing in specialized dental tissues, such as dental pulp, periodontium, apical papilla, dental follicle and so forth. Standard methods have been established to isolate and identify these stem cells.
Yi, Shuai +7 more
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Epigenetics of Dental Stem Cells
2016Dental stem cells (DSCs) offer significant potential for use in regenerative procedures and therefore identifying cellular regulators that control SC fate is critical to devising novel therapeutic strategies. Stem cell lineage-commitment and differentiation are regulated by an intricate network of host and environmental factors of which epigenetic ...
Henry F. Duncan, Paul R. Cooper
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