Results 131 to 140 of about 131,553 (328)
Neural Plasticity, 2008 Long-term recognition memory requires protein synthesis, but little is known about the coordinate regulation of specific genes. Here, we examined expression of the plasticity-associated immediate early genes (Arc, Zif268, and Narp) in the dentate gyrus ...
Jonathan Soulé +5 more
doaj +1 more source
The Dentate Gyrus: Its Value for Depression [PDF]
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 2021 Jasper O. Nuninga, Iris E.C. Sommer
openaire +3 more sources
Journal of Neuroscience, 1997 These studies were designed to determine whether adult neurogenesis occurs in the dentate gyrus of the tree shrew, an animal phylogenetically between insectivores and primates, and to explore the possibility that this process is regulated by stressful ...
E. Gould +4 more
semanticscholar +1 more source
Glia, EarlyView.Spatial transcriptomic analysis unravels the mechanisms by which HDACi ameliorates neuroinflammation and enhances neuroprotection by modulating the expression of microglial transcriptomes in the ischemic mouse brain. ABSTRACT Ischemic stroke significantly contributes to global morbidity and disability through a cascade of neurological responses ...
Kevin Jayaraj +5 more
wiley +1 more source
MDMA Increases Excitability in the Dentate Gyrus: Role of 5HT2A Receptor Induced PGE2 Signaling [PDF]
, 2016 MDMA is a widely abused psychostimulant which causes release of serotonin in various forebrain regions. Recently, we reported that MDMA increases extracellular glutamate concentrations in the dentate gyrus, via activation of 5HT2A receptors.
Chiaia, Nicolas +4 more
core +1 more source
Dentate gyrus is needed for memory retrieval
Molecular PsychiatryAbstractThe hippocampus is crucial for acquiring and retrieving episodic and contextual memories. In previous studies, the inactivation of dentate gyrus (DG) neurons by chemogenetic- and optogenetic-mediated hyperpolarization led to opposing conclusions about DG’s role in memory retrieval.
Alejandro Carretero-Guillén +10 more
openaire +6 more sources
Extrinsic afferent systems to the dentate gyrus [PDF]
, 2007 The dentate gyrus is the first stage of the intrahippocampal, excitatory, trisynaptic loop, and a primary target of the majority of entorhinal afferents that terminate in a laminar fashion on granule cell dendrites and carry sensory information of multiple modalities about the external world.
Tibor Hajszan +2 more
openaire +3 more sources
Nature Communications, 2014 Amyloid plaques and tau tangles are common pathological hallmarks for Alzheimer’s disease (AD); however, reducing Aβ production failed to relieve the symptoms of AD patients. Here we report a high GABA (γ-aminobutyric acid) content in reactive astrocytes
Zheng Wu +3 more
semanticscholar +1 more source
Neuroanatomical and functional correlates in borderline personality disorder: A narrative review
Ibrain, Volume 11, Issue 1, Page 19-31, Spring 2025.Borderline personality disorder (BPD) is considered a dysfunctional, stable, and pervasive alteration in personality functioning with the inability to adapt to the environment, mental rigidity, and ego‐syntonic, and like all personality disorders is a consistent pattern of inner experience and behavior that deviates markedly from the expectations of ...
Giulio Perrotta
wiley +1 more source
Toward a full-scale computational model of the rat dentate gyrus
Frontiers in Neural Circuits, 2012 Recent advances in parallel computing, including the creation of the parallel version of the NEURON simulation environment, have allowed for a previously unattainable level of complexity and detail in neural network models.
Calvin James Schneider +2 more
doaj +1 more source