Results 131 to 140 of about 63,053 (291)

Lipopolysaccharide Inhibits Long Term Potentiation in the Rat Dentate Gyrus by Activating Caspase-1 [PDF]

, 2000
Emily Vereker, Veronica A. Campbell, Elizabeth Roche, Edel McEntee, Marina A. Lynch   +4 more
openalex   +1 more source

Contribution of perineuronal nets to hyperexcitability in pilocarpine‐induced status epilepticus

Epilepsia, EarlyView.
Abstract Objective Changes in extracellular matrix (ECM) and highly condensed ECM structures called perineuronal nets (PNNs) have been reported in human patients with epilepsy as well as some animal models of epilepsy. We studied potential ECM changes in a mouse model of pilocarpine‐induced status epilepticus (PISE) and their potential contributions to
AnnaLin M. Woo, Erik J. Fleischel, Dipan C. Patel, Harald Sontheimer   +3 more
wiley   +1 more source

Cholecystokinin and cholecystokinin antagonists enhance postsynaptic excitability in the dentate gyrus

, 1988
Christopher M. Sinton
openalex   +1 more source

CREB Phosphorylation Coincides with Transient Synapse Formation in the Rat Hippocampal Dentate Gyrus Following Avoidance Learning [PDF]

, 2000
C. O’Connell, Helen C. Gallagher, A O'Malley, Mary Bourke, Ciaran M. Regan   +4 more
openalex   +1 more source

Automatic detection of hippocampal sclerosis in patients with epilepsy

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to develop and validate an automatic, artificial intelligence‐enhanced software tool for hippocampal sclerosis (HS) detection, using a variety of standard magnetic resonance imaging (MRI) protocols from different MRI scanners for routine clinical practice.
Marcus Belke, Felix Zahnert, Mirja Steinbrenner, Mustafa Halimeh, Gadi Miron, Panagiota‐Eleni Tsalouchidou, Louise Linka, Boris Keil, Andreas Jansen, Vincent Möschl, André Kemmling, Christopher Nimsky, Felix Rosenow, Katja Menzler, Susanne Knake   +14 more
wiley   +1 more source

Dentate gyrus granule cells are a locus of pathology in Scn8a developmental encephalopathy

Neurobiology of Disease
Gain-of-function mutations in SCN8A cause developmental and epileptic encephalopathy (DEE), a disorder characterized by early-onset refractory seizures, deficits in motor and intellectual functions, and increased risk of sudden unexpected death in ...
Wenxi Yu, Sophie F. Hill, Limei Zhu, Yiannos Demetriou, Faith Reger, Joanna Mattis, Miriam H. Meisler   +6 more
doaj   +1 more source

WONOEP XVII appraisal: Targeting network excitability beyond the synapse ‐Neurotransmitter, ionic, and electro ‐diffusions

Epilepsia, EarlyView.
Abstract Epilepsy affects approximately 1% of the population worldwide, and although medications are effective in the majority of cases, seizures persist in approximately 30% of patients. Despite the effort to develop new antiseizure drugs, the rate of pharmacoresistance in patients has not diminished over the past 3 decades. There is thus a real unmet
Vincent Magloire, Marco de Curtis, Jeffrey Noebels, Gilles Huberfeld, Piotr Suffczynski, Vadym Gnatkovsky, Olga Tyurikova, Dominique Durand, David C. Henshall, Cian McCafferty   +9 more
wiley   +1 more source

Epidermal growth factor and basic fibroblast growth factor promote the generation of long-term potentiation in the dentate gyrus of fimbria-fornix lesioned rats.

, 1991
Jun‐ichi Ishiyama, Hiroshi Saito, Kazuho Abe   +2 more
openalex   +1 more source

Adult Spinal Cord Stem Cells Generate Neurons after Transplantation in the Adult Dentate Gyrus [PDF]

, 2000
Lamya S. Shihabuddin, Philip J. Horner, Jasodhara Ray, Fred H. Gage   +3 more
openalex   +1 more source

Comorbidities in the mouse model of temporal lobe epilepsy induced by intrahippocampal kainate

Epilepsia, EarlyView.
Abstract Objective Mesial temporal lobe epilepsy (MTLE) is generally associated with cognitive and psychiatric comorbidities. Here we examined whether similar comorbidities are observed in mice injected with kainate in the dorsal hippocampus, a model known to recapitulate many features of human MTLE, and if these comorbidities are sex dependent ...
Loan Samalens, Camille Beets, Clothilde Courivaud, Philippe Kahane, Antoine Depaulis   +4 more
wiley   +1 more source