Results 111 to 120 of about 76,364 (261)
Precision Medical Sciences, EarlyView.Cancer therapies can trigger neuroinflammation and disrupted neuroplasticity, contributing to cognitive impairment and psychological distress in survivors. Stem cells (NSCs/MSCs) and their extracellular vesicles may restore neural niches via trophic support, immunomodulation, synaptic remodeling, and vascular repair, but require rigorous safety, dosing,
Xinyi Yang
wiley +1 more source
HE-staining of dentate gyrus at each developmental stage.
, 2014 (A) HE-staining of dentate gyrus in five-week-old mice. Bars = 50 μm. a, ZFP521+/+ mouse; b, ZFP521Δ/Δ mouse. Note that the density of neuronal cells was obviously lower and the neuronal cell layer was more obscure in ZFP521Δ/Δ mouse. (B) HE-staining of
Etsuko Matsubara (543875) +11 more
core +1 more source
Small, EarlyView.We present a pathology‐responsive, activity‐based prodrug strategy that tackles multiple hallmarks of Alzheimer's disease (AD). Rationally designed BE compounds convert under oxidative stress into redox‐active aminophenols, neutralizing ROS and redirecting both metal‐free and metal‐bound Aβ aggregation.
Jimin Lee +13 more
wiley +1 more source
Transformation of spatial representations along hippocampal circuits
iScienceSummary: The hippocampus is thought to provide the brain with a cognitive map of the external world by processing various types of spatial information.
Bérénice Gandit +6 more
doaj +1 more source
Effects of Tamoxifen on Morphological and Ultrastructural Aspects of Developing Hippocampus of Rat [PDF]
Background: Tamoxifen treatment induced cell death in the hippocampus formation of the prenatal and postnatal rat. The present study delineates the effect of tamoxifen on developing hippocampus in prenatal, postnatal and full term neonate rats received
کردستانی شرق, بهاره +2 more
core
Spine morphology of molecular layer of dentate gyrus.
, 2015 (A) Graphical representation of spine density/30μm of molecular layer of dentate gyrus; (B) Representative images of DIL dye staining of of molecular layer of dentate gyrussubarea where the mushroom spines are represented by yellow colour, thin spines by
Sunetra Sase (814052) +7 more
core +1 more source
“White and Clear” (WaC): A tunable hydrophilic tissue clearing strategy for multi‐species 3D imaging
VIEW, EarlyView.Optical tissue clearing methods help scientists make tissues transparent to image structures deep inside organs in 3D, but many existing techniques are limited in performance and difficulty. In this study, we developed an optimized clearing method called WaC (White and Clear), which improves upon existing techniques by combining efficient tissue ...
Vicente Llorente +12 more
wiley +1 more source
Addiction, EarlyView.Abstract Background and aims Cannabis is the most widely used illicit drug worldwide and is often co‐used with tobacco, the leading cause of preventable death. Although cannabis and tobacco have distinct neurobiological actions, their associations with brain volumes are unclear.
Katherine Sawyer +16 more
wiley +1 more source
Efeito de uma única injeção intracerebroventricular de imipramina sobre o comportamento e a neurogênese no hipocampo de camundongos suíços adultos: influência da dose, do ambiente e do intervalo entre tratamento e sacrifício [PDF]
, 2012 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação Multicêntrico em Ciências Fisiológicas, Florianópolis, 2011A imipramina é um fármaco antidepressivo que promove alterações ...
Podolan, Martina
core
On how the dentate gyrus contributes to memory discrimination
, 2017 SummaryThe dentate gyrus (DG) is crucial for behaviorally discriminating similar spatial memories, predicting that dentate gyrus place cells change (“remap”) spatial tuning (“place fields”) for memory discrimination.
Milenna T. van Dijk, Andre A. Fenton
core +1 more source