Results 91 to 100 of about 76,364 (261)
Absence seizures: Update on signaling mechanisms and networks
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley +1 more source
Long-term recognition memory requires protein synthesis, but little is known about the coordinate regulation of specific genes. Here, we examined expression of the plasticity-associated immediate early genes (Arc, Zif268, and Narp) in the dentate gyrus ...
Jonathan Soulé +5 more
doaj +1 more source
Toward a full-scale computational model of the rat dentate gyrus
Recent advances in parallel computing, including the creation of the parallel version of the NEURON simulation environment, have allowed for a previously unattainable level of complexity and detail in neural network models.
Calvin James Schneider +2 more
doaj +1 more source
Neonatal seizures and GABAergic drugs: Scylla and Charybdis?
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson +2 more
wiley +1 more source
Thioperamide-induced Antinociception is Mediated through Endogenous Opioid System in the Dentate Gyrus of Adult Rats [PDF]
The present study investigated the effects of intra-dentate gyrus microinjection of naloxone (an opioid antagonist) and thioperamide (an antagonist of histamine H3 receptors) in the formalin test in rats. Subcutaneous injection of formalin (50 µl, 2.5 %)
Emad Khalilzadeh +3 more
doaj
Neuroanatomical and functional correlates in borderline personality disorder: A narrative review
Borderline personality disorder (BPD) is considered a dysfunctional, stable, and pervasive alteration in personality functioning with the inability to adapt to the environment, mental rigidity, and ego‐syntonic, and like all personality disorders is a consistent pattern of inner experience and behavior that deviates markedly from the expectations of ...
Giulio Perrotta
wiley +1 more source
Background and Objective: Hippocampus is the main region in cortex of the brain that involved in epilepsy. This study was done to determine the effect of intraventricular injection of vitamin C on histological structure of dentate gyrus of hipocampus in ...
R Golmohammadi, B Kmalimansh
doaj
We are rapidly approaching a better understanding of the mechanisms that allow our brains to form distinct representations for similar events or episodes. McHugh et al.
Leutgeb, Jill K., Moser, Edvard I.
core +1 more source
Abstract In recent years, the clinical treatment and symptom management of neurological disorders have faced significant challenges due to the high complexity of the nervous system's structure and function. Against this backdrop, physical stimulation techniques have emerged as a vital complementary approach to traditional pharmacological treatments and
Wanying Li, Liqun Chen
wiley +1 more source
Abstract Background The accurate assessment of infraosseous periodontal defects is crucial for effective diagnosis and treatment planning. Cone‐beam computed tomography (CBCT) enables detailed imaging of these defects; however, to leverage their full potential, CBCT images must be reconstructed in 3 dimensions (3D).
Daniel Palkovics +8 more
wiley +1 more source

