Results 71 to 80 of about 76,364 (261)

Neuronal differentiation and tissue engineering strategies for central neurous system injury repair

BMEMat, EarlyView.
This review outlines tissue engineering advances for central nervous system (CNS) injury treatment, focusing on three core components: seed cells, inductive factors, and scaffold materials, with evaluation of their respective strengths and limitations. Tissue engineering for CNS injury repair.
Zhuqing Xia, Jinghui Zhang, Na Ren, Shuping Wang, Congcong Zhang, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Chao Liu, Chunhui Sun, Jingang Wang   +9 more
wiley   +1 more source

Estradiol and GPER Activation Differentially Affect Cell Proliferation but Not GPER Expression in the Hippocampus of Adult Female Rats.

PLoS ONE, 2015
Estradiol increases cell proliferation in the dentate gyrus of the female rodent but it is not known whether the G protein-coupled estrogen receptor (GPER), a membrane receptor, is involved in this process, nor whether there are regional differences in ...
Paula Duarte-Guterman, Stephanie E Lieblich, Carmen Chow, Liisa A M Galea   +3 more
doaj   +1 more source

Bacterial meningitis causes two distinct forms of cellular damage in the hippocampal dentate gyrus in infant rats.

, 2003
Bacterial meningitis causes neurological sequelae in up to 50% of survivors. Two pathogens known for their propensity to cause severe neurological damage are Streptococcus pneumoniae and group B streptococci.
Imboden, Hans, Bifrare, Yoeng-Delphine, Täuber, Martin G., Leib, Stephen L, Gianinazzi, Christian   +4 more
core   +1 more source

A neuro‐behavioural model of neophobia

Biological Reviews, EarlyView.
ABSTRACT Fear can be defined as the internal neurological state that releases a repertoire of behaviours an animal performs to reduce the effect of an aversive factor. Neophobia, the fear of novelty, is a fundamental behavioural trait observed across a wide range of species from arthropods to humans.
Arik Dorfman, Aziz Subach, Inon Scharf
wiley   +1 more source

Expression of TLR8 in the dentate gyrus.

, 2022
Double immunofluorescence of TLR8 (red fluorescence; a, d, g) with the microglia marker transmembrane protein 119 (Tmem-119; b, c), the astrocyte marker glial fibrillary acidic protein (GFAP; e, f), and neuron-specific nuclear protein (NeuN; h, i), a ...
Meinrad Drexel (12501722), Lennart Seizer (12501713), Sadegh Rahimi (12501716), Sandra Santos-Sierra (12501719)   +3 more
core   +1 more source

The segregation of Calb1, Calb2, and Prph neurons reveals distinct and mixed neuronal populations and projections to hair cells in the inner ear and central nuclei

Developmental Dynamics, EarlyView.
Three populations of hair cells have a distinct expression of Calb1 and Calb2. (A, A′D) The central is highly positive for Calb1 while surrounding HC are positive for Calb2. Later, a calyx forms primarily with Calb1. (B, B′, D′, D″) Saccule and utricle start out positive for Calb2 but will upregulate the Calb1 in the striola that is primarily forming ...
Jeong Han Lee, Ebenezer N. Yamoah, Jennifer Kersigo, Karen Elliott, Niya LaRoda, Gabriela Pavlinkova, Bernd Fritzsch   +6 more
wiley   +1 more source

Ethanol neurotoxicity and dentate gyrus development

, 2008
Maternal alcohol ingestion during pregnancy adversely affects the developing fetus, often leading to fetal alcohol syndrome (FAS). One of the most severe consequences of FAS is brain damage that is manifested as cognitive, learning, and behavioral ...
Wang, Zhi-Yu, Wilce, Peter A., Takeuchi, Yoshiki, Sumitani, Kazunori, Bedi, Kuldip S., Itoh, Susumu, Miki, Takanori, Kusaka, Takashi, Matsumoto, Yoshiki, Warita, Katsuhiko, Yokoyama, Toshifumi   +10 more
core   +1 more source

Bidirectional GABAergic control of AP firing in newly-generated young granule cells of the adult hippocampus [PDF]

, 2015
Gamma-aminobutyric acid (GABA) is the first transmitter which provides synaptic input to newly generated neurons. In the first 2-3 weeks after mitosis, young neurons show an elevated intracellular chloride concentration due to the expression of the NKCC1
Heigele, Stefanie
core   +1 more source

Unique deficits in place coding across subfields of the hippocampus in a mouse model of temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective Memory problems are comorbid with temporal lobe epilepsy (TLE). Animal models of TLE reveal impairments in spatial firing fields of hippocampal place cells, providing a potential neural substrate for memory problems. Each subfield of the hippocampus carries out unique aspects of spatial memory, yet little is known about how ...
Brittney L. Boublil, Margaret M. Donahue, Cathy B. Dang, Gergely Tarcsay, Laura A. Ewell   +4 more
wiley   +1 more source

Usp9x-deficiency disrupts the morphological development of the postnatal hippocampal dentate gyrus [PDF]

, 2016
Within the adult mammalian brain, neurogenesis persists within two main discrete locations, the subventricular zone lining the lateral ventricles, and the hippocampal dentate gyrus.
Alexander, S, Burne, THJ, Wood, SA, Oishi, S, Iyer, S, Harvey, TJ, Premarathne, S, Piper, M, Dixon, C   +8 more
core   +2 more sources