Results 161 to 170 of about 72,047 (256)

The MacBrain Resource Center (MBRC) rhesus macaque postnatal brain histology datasets: Enabling new discoveries through NHP tissue and digital data Repositories

open access: yesJournal of Anatomy, EarlyView.
The MacBrain Resource Center (MBRC) postnatal rhesus macaque brain histology datasets are organized into Collections that promote cost‐effective de novo research. This article provides examples from Collections 5, 6, and 7 and describes the histo‐ and immunohistochemical (IHC) processing of materials for Collection 6.
Valeria Mendoza‐Silva   +19 more
wiley   +1 more source

From mouth to brain: Linking periodontal and peri‐implant dysbiosis to systemic inflammation and neuropathology

open access: yesPeriodontology 2000, EarlyView.
Abstract Background/Aim Growing evidence suggests that imbalances occurring within the human microbiota and deregulation of the host immune response may play a significant role in the development of neurodegenerative diseases. Materials and Methods A comprehensive narrative review of the latest experimental, clinical, and epidemiological insights was ...
Emilio A. Cafferata   +3 more
wiley   +1 more source

Effects of Oestrogen on Ischemia-induced Neurogenesis in the Dentate Gyrus of Rats

open access: yes, 2007
To study the effects of oestrogen on ischemia?induced neurogenesis in the hippocampal dentate gyrus, thirty-two adult male rats were randomly divided into four groups:the control surgery group with oestrogen administration (SE), the control surgery group
WANG, Ming, LU, Ya-ping
core   +1 more source

Peri‐implantitis and systemic inflammation: Current evidence, biological plausibility, and research gaps

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Peri‐implantitis is a biofilm‐associated inflammatory condition characterized by peri‐implant mucosal inflammation and progressive bone loss. The prevalence of peri‐implantitis continues to rise among patients with dental implants. Although peri‐implantitis and periodontitis share similar inflammatory phenotypes, histopathological ...
Yumeng Yan   +2 more
wiley   +1 more source

Mitochondrial Ca2+ uniporter haploinsufficiency leads to sexually dimorphic redox imbalance and metabolic remodelling in the mouse brain

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The genetic inactivation of one Mcu allele leads to sex‐specific changes in neuronal function in adult mice, that is, the firing of action potentials and the relationship between cytosolic and mitochondrial Ca2+ levels. The ability to produce NAD(P)H by stimulated neural tissue is largely preserved in male mice but delayed in ...
Jenna Gray   +16 more
wiley   +1 more source

Characterization of postnatal brain injury and behavioural deficits in a rat model of placental insufficiency‐induced fetal growth restriction

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Fetal growth restriction (FGR) is a common pregnancy complication associated with long‐term neurodevelopmental impairments. Using the reduced uterine perfusion pressure (RUPP) rat model of placental insufficiency‐induced FGR, this study demonstrates that FGR leads to persistent anatomical, histological and behavioural ...
Judit Alhama‐Riba   +8 more
wiley   +1 more source

Molecular Control of Neural Stem Cell Quiescence in the Adult Zebrafish Telencephalon: Established Mechanisms and an Integrative Hypothesis

open access: yesGlia, Volume 74, Issue 12, December 2026.
Adult zebrafish radial glia quiescence is controlled by at least four mechanisms: Notch3, BMP‐Id1, Nr2f1b and Midkine‐a. We propose these act as partially redundant inputs, biased along the antero‐posterior axis that set quiescence depth. ABSTRACT The zebrafish telencephalon is an excellent model for adult neurogenesis under physiological and ...
Mathilde Hoareau   +2 more
wiley   +1 more source

Neuronal Overexpression of Glycogen Synthase Kinase‐3β Accelerates Age‐Related Glial, Vascular, and Inflammatory Remodeling of the Murine Dentate Gyrus

open access: yesGlia, Volume 74, Issue 12, December 2026.
Aging induces layer‐specific changes in glial populations and vascular organization across the dentate gyrus. Neuronal GSK‐3β overexpression accelerates age‐related remodeling of the dentate gyrus neurogenic niche. GSK‐3β‐overexpressing mice show premature subgranular zone (SGZ) astrocyte loss, altered microglia and oligodendroglia, and vascular ...
Ana V. Prádanos‐Senén   +2 more
wiley   +1 more source

An imputation method for single‐cell RNA sequencing data based on a parallel gated recurrent unit neural network

open access: yesQuantitative Biology, Volume 14, Issue 4, December 2026.
Abstract Single‐cell RNA sequencing (scRNA‐seq) generates high‐dimensional transcriptomic data but is severely affected by dropout events, which obscure true gene–gene relationships. These missing values introduce bias into downstream analyses, complicate data processing, and reduce analytical efficiency.
Shuang Xu   +3 more
wiley   +1 more source

Towards an Understanding of the Dentate Gyrus Hilus

open access: yesHippocampus
ABSTRACTFor many years, the hilus of the dentate gyrus (DG) was a mystery because anatomical data suggested a bewildering array of cells without clear organization. Moreover, some of the anatomical information led to more questions than answers.
openaire   +2 more sources

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