Results 161 to 170 of about 62,950 (262)

Sleep Deprivation and Neuronal Hyperexcitation Share Transcriptomic Signatures

Neuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.
This study demonstrated that sleep deprivation induces transcriptomic changes in mice and rats similar to those observed in various models of neuronal hyperexcitation. These findings suggest a potential link between sleep deprivation and neuropsychiatric disorders.
Markos Michail Chatzigiannis, Hideo Hagihara, Tsuyoshi Miyakawa   +2 more
wiley   +1 more source

High-altitude hypoxia drives dentate gyrus neuronal vulnerability through an IL1α-astrocyte-SLC1A2 pathway. [PDF]

J Neuroinflammation
Zhang Y, Ni Z, Xia T, Zhang N, Shen P, Wang N, Bai Z, Ma Y, Wang R, Sun D, Li S, Huangfu C, Gao Y, Zhou W.   +13 more
europepmc   +1 more source

A Review of the Therapeutic Potential of Stem Cell‐Derived Nanocarriers to Treat Neurological Disorders

ChemistryOpen, Volume 15, Issue 9, September 2026.
Neurological disorders (NDs) are characterized by substantial loss of specific neurons, with Alzheimer's and Parkinson's diseases being the most frequent NDs and nearly 99% of all “foreign substances” are prohibited from entering the brain by the blood‐brain barrier (BBB) and the blood‐cerebrospinal fluid barrier (CFB).
Nnamdi Ikemefuna Okafor, Ahmed Abdelgader, Magdi Abobaker, Yahya E. Choonara   +3 more
wiley   +1 more source

Increased Binding of [18F]Nifene, a PET Imaging Probe for α4β2* Nicotinic Acetylcholinergic Receptors in Hippocampus–Subiculum of Postmortem Human Parkinson's Disease Brain

Synapse, Volume 80, Issue 5, September 2026.
[18F]Nifene, a PET imaging probe for α4β2* nicotinic acetylcholine receptors, was used to discretely measure changes in hippocampus (HP) and subiculum (SUB) of postmortem Parkinson's disease (PD) cases compared to cognitively normal (CN) cases. Significant increased [18F]nifene binding in PD was observed.
Jogeshwar Mukherjee, Fariha Karim, Allyson Ngo, Christopher Liang, Geidy E. Serrano, Thomas G. Beach   +5 more
wiley   +1 more source

Impact of O-GlcNAcylation Elevation on Mitophagy and Glia in the Dentate Gyrus. [PDF]

J Neurochem
Kramer J, Fu S, Ouyang X, Rohwer E, Chatham JC, Young ME, Darley-Usmar V, Zhang J.   +7 more
europepmc   +1 more source

Sex and Chronic Stress Alter the Distribution of Corticotropin‐Releasing Factor Receptor in Rat Hippocampus Following Oxycodone Conditioned Place Preference

Synapse, Volume 80, Issue 5, September 2026.
Chronic stress modifies the effect of oxycodone conditioned place preference (Oxy CPP) on corticotropin releasing factor 1 (CRFR1) subcellular distributions in hippocampal subregions. These stress‐ and oxycodone‐induced changes in CRFR1 density may influence sex differences in hippocampal learning and memory processes both at baseline and following Oxy
Dana N. Silberstein, Zoha Baig, Batsheva Rubin, Fangmin Yu, Joshua Kogan, Jason D. Gray, Yan Zhou, Teresa A. Milner   +7 more
wiley   +1 more source

Increased dendritic inhibition of dentate gyrus granule cells in a mouse model of Down syndrome. [PDF]

Front Cell Neurosci
Gutmann N, Häussler U, Mersi A, Follo M, Bischofberger J, Schulz JM.   +5 more
europepmc   +1 more source

Synaptic plasticity in the perforant pathway drives inhibitory reorganization enhancing dentate gyrus functionality. [PDF]

iScience
Estarellas C, Álvarez-Salvado E, Pérez-Cervera L, Caramés JM, Pérez-Montoyo E, López-Madrona VJ, Garcia-Hernandez R, Mirasso CR, Canals S.   +8 more
europepmc   +1 more source

Associations between TMEM106B C‐terminal fragment aggregation, age, and TDP‐43 or tau pathology

Brain Pathology, Volume 36, Issue 5, September 2026.
TMEM106B C‐terminal fragment (CTF) aggregation represents an age‐associated, common, diffuse phenomenon emerging after midlife with a weak association with TDP‐43 or tau pathology. These findings suggest that TMEM106B fibrillization may define a distinct axis of protein aggregation in the aging human brain. Abstract Transmembrane protein 106B (TMEM106B)
Albert Acewicz, Sylwia Tarka, Michał Grzegorczyk, Radosław Rzepliński, Teresa Wierzba‐Bobrowicz, Tomasz Stępień   +5 more
wiley   +1 more source

A Quantitative Comparison of Medial and Coronal Dentate Gyrus Microdissection Strategies and a Softening-Based Workflow for Reproducible Tissue Procurement. [PDF]

Life (Basel)
Koç T, Öztürk NC.
europepmc   +1 more source