British Journal of Pharmacology, Volume 183, Issue 18, Page 5440-5457, September 2026.Background and purpose Adult neurogenesis is a tightly regulated process affected by both cannabinoid receptors (CB1 and CB2) and adenosine 2A (A2A) receptors, both of which modulate neural progenitor cell activity. While emerging evidence suggests an interaction between these neuromodulatory systems, the extent and mechanism of their interplay in ...
Rui S. Rodrigues +8 more
wiley +1 more source
In Utero Electroporation Uncovers an Early-Differentiating Subset of Dentate Gyrus Progenitors. [PDF]
Cell Mol NeurobiolShinohara HM, Takahashi T.
europepmc +1 more source
Histopathological Evidence of Neurodegenerative Pathology in Epilepsy: A Systematic Review
Annals of Clinical and Translational Neurology, Volume 13, Issue 8, Page 1530-1542, August 2026.ABSTRACT Epilepsy affects > 50 million people worldwide and is associated with a disproportionate burden of cognitive impairment. Emerging evidence suggests that neurodegenerative proteinopathies, particularly hyperphosphorylated tau (p‐tau) and amyloid‐β (Aβ), may contribute to cognitive dysfunction in people with epilepsy (PWE), even in the absence ...
Syeda Amrah Hashmi +7 more
wiley +1 more source
Context-dependent modulation of LTP and BDNF/TrkB signaling in the dentate gyrus following combined progressive aerobic and rotarod training in male wistar rats. [PDF]
IBRO Neurosci RepSadeghi M, Komaki A, Nazem F.
europepmc +1 more source
Advanced Biology, Volume 10, Issue 8, August 2026.Ghrelin excites the dentate gyrus (DG) granule cells via GHSR‐mediated modulation of diverse ionic channels and activation of D1R, cAMP, and EPAC2. Similarly, overnight calorie restriction alters neuronal excitability in a ghrelin‐dependent manner. Infusion of ghrelin directly into the DG improves short‐term spatial memory in the Y‐maze, providing ...
Chidiebele S. Oraegbuna +3 more
wiley +1 more source
Electroconvulsive Shock Induces Greater Plasticity of Dentate Gyrus Neurons Born in Adulthood Than Those Born in Development. [PDF]
Eur J NeurosciZhang TR +5 more
europepmc +1 more source
Advanced Materials, Volume 38, Issue 43, 3 August 2026.A soft–hard tri‐layer composite electrolyte that couples fast Li+ transport with reinforced interfacial stability to enable high‐conductivity, mechanically robust, dendrite‐free lithium‐metal batteries. ABSTRACT The development of solid polymer electrolytes is central to safe, high‐energy lithium‐metal batteries (LMBs); however, persistent challenges ...
Fazal Ur Rehman +9 more
wiley +1 more source
<i>Fmr1</i> Deletion and Early-Life Stress Interact to Increase Cell Proliferation and Glial Populations at the Expense of Immature Neurons in the Adult Dentate Gyrus. [PDF]
Int J Mol SciLatchney SE +4 more
europepmc +1 more source
mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling
Advanced Science, Volume 13, Issue 43, 3 August 2026.Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim +4 more
wiley +1 more source
The functional role of opioidergic system within the ventral tegmental area and the dentate gyrus of hippocampus in modulation of the persistent inflammatory pain in the rats. [PDF]
IBRO Neurosci RepSaghafi M, Azizbeigi R, Haghparast A.
europepmc +1 more source