Results 171 to 180 of about 72,047 (256)

Intrinsic Activity Reductions and Cerebello‐Cortical Diaschisis‐Like Mechanism in Friedreich Ataxia: An fALFF Resting‐State fMRI Study

open access: yesBrain and Behavior, Volume 16, Issue 11, November 2026.
Abstract Background Friedreich ataxia (FA) is characterized by progressive degeneration of the cerebellum and its output pathways, particularly the dentato–thalamo–cortical system, leading to motor impairment and the cerebellar cognitive affective syndrome (CCAS).
Naeije Gilles   +2 more
wiley   +1 more source

Beneficial Role of Natural Polyphenols Against Epilepsy: Greasing the Wheels of Pharmacotherapy Research for Epilepsy

open access: yesFood Frontiers, Volume 7, Issue 6, November 2026.
ABSTRACT Epilepsy is the most disabling neurological disease that affects all economic classes, age groups, regions, and races. Although many antiseizure drugs are approved for epilepsy treatment, they fail to work in about 30%–40% of patients. Thus, there is a great need to identify better pharmacological agents to treat epilepsy.
Janakiraman Pillai Udaiyappan   +3 more
wiley   +1 more source

Effects of Rosmarinic Acid on L‐Methionine‐Induced Behavioral Impairments and Disruptions in Hippocampal Neurogenesis in the Adult Rat

open access: yesFood Science &Nutrition, Volume 14, Issue 11, November 2026.
“Excessive L‐methionine (L‐met) intake impairs spatial (NOL) and recognition (NOR) memory, suppresses cell proliferation and vascular‐associated proliferating cells (Ki‐67 and Ki‐67/RECA‐1) and neuronal survival (BrdU/NeuN), and increases cell‐cycle arrest (p21) in the hippocampal dentate gyrus of adult rats.
Salinee Naewla   +7 more
wiley   +1 more source

Persisting Region‐Specific Microglia Activation and Synaptic Imbalance During Remission in a DSS‐Induced Colitis Model

open access: yesGlia, Volume 74, Issue 11, November 2026.
Relapsing colitis region‐specific microglial states beyond remission. Cortical microglia remain pro‐inflammatory and synapse‐disruptive, while hippocampal microglia shift toward a reparative program that maintains neuronal circuit stability. ABSTRACT Ulcerative colitis (UC) patients experience cycles of active gut inflammation and remission, with ...
Lorena Morton   +6 more
wiley   +1 more source

Dentate gyrus

open access: yes, 2015
Henry Knipe, Jeremy Jones
openaire   +1 more source

Glial Dysfunction and Memory Impairments in a Model of Pediatric Obstructive Sleep Apnea

open access: yesGlia, Volume 74, Issue 11, November 2026.
Generation and analysis of an snRNA‐seq atlas of the hippocampus in POSA. Validation of reduced protein expression of six genes across four cell types. Cellular‐level investigation of aberrant glial function in POSA using transgenic reporter mice. ABSTRACT Pediatric obstructive sleep apnea (POSA) is a common childhood disease that often causes aberrant
Michael R. Williamson   +13 more
wiley   +1 more source

Cell Surface Markers Identify Astrocyte Subpopulations in the Adult Hippocampus With a Heterogeneous Response to Aging

open access: yesGlia, Volume 74, Issue 11, November 2026.
ATP1B2 and GLAST identify two astrocyte subpopulations in the hippocampus with distinct molecular signatures. Transcriptomic shifts during aging differ between both subpopulations. Aged ATP1B2+ astrocytes rewire their metabolism while double‐positive aged astrocytes display a reduced synaptogenic capability.
Lucía Casares‐Crespo   +6 more
wiley   +1 more source

Reelin and Notch1 Cooperate in the Development of the Dentate Gyrus

open access: yes, 2009
The development of the hippocampal dentate gyrus is a complex process in which several signaling pathways are involved and likely interact with each other.
Basak, O.   +4 more
core  

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