Results 181 to 190 of about 72,047 (256)

Adolescent Ethanol Exposure Disrupts the Mature Phenotype of Surviving Neuroprogenitors in Female Mice

Hippocampus, Volume 36, Issue 6, November 2026.
ABSTRACT Rodent models of human adolescent binge drinking persistently reduce adult neurogenesis and induce innate immune signaling cascades, suggesting long‐lasting dysfunction in the hippocampal neurogenic niche. Nevertheless, many neuroprogenitors survive, and the impact of adolescent ethanol on the mature phenotype of these surviving neurons is ...
Kaitlyn Campbell, Madison McDowell, Eymani Alston, Hunter Kelley, Michael Kasten, Paul B. Manis, Fulton Crews, Victoria Macht   +7 more
wiley   +1 more source

Differential neurogenesis in the adult rat dentate gyrus

, 2008
xvi, 125 leaves : ill. ; 29 cm. --Adult neurogenesis is a fundamental feature of mammalian nervous systems. Curiously, neurogenesis in the dentate gyrus is typically regarded as homogenous.
University of Lethbridge. Faculty of Arts and Science, Melvin, Neal   +1 more
core  

Mental Scene and Memory Construction and the Hippocampus

Hippocampus, Volume 36, Issue 6, November 2026.
ABSTRACT A neurocomputational theory of scene and memory construction during memory recall, prospective thinking, and autobiographical memory is described. The theory describes the nature of the representation of scenes using spatial view cells in a continuous attractor network in the medial parahippocampal cortex, and how the location in the scene ...
Edmund T. Rolls
wiley   +1 more source

Temporal Interference Modulates Medial Temporal and Frontoparietal Activity During Mnemonic Discrimination: A High‐Resolution Whole‐Brain fMRI Investigation

Hippocampus, Volume 36, Issue 6, November 2026.
ABSTRACT Mnemonic discrimination—the ability to distinguish between existing memories and similar new inputs—supports accurate memory in the face of interference (e.g., in a card game, recognizing that the card you are currently seeing, the King of Hearts, is distinct from the King of Diamonds you encountered earlier in the same hand).
Min Sung Seo, Rebecca L. Wagner, Jordan D. Chamberlain, Kelsey L. Canada, Nancy A. Dennis   +4 more
wiley   +1 more source

Mapping Projectome Heterogeneity of Subiculum Neuron Cell Types

Hippocampus, Volume 36, Issue 6, November 2026.
ABSTRACT The subiculum (SUB) is the main output structure of the hippocampus, influencing diverse behaviors through its widespread cortical and subcortical connections. Our previous work creating the mouse Hippocampus Gene Expression Atlas (HGEA) identified four genetically distinct cellular layers across five columnar domains in the SUB, with gene ...
Ann W. Saustad, Michael S. Bienkowski
wiley   +1 more source

Quantitative Assessment of Mesoscale Cellular Order and Organization in the Mouse Hippocampus

Hippocampus, Volume 36, Issue 6, November 2026.
ABSTRACT The hippocampus is characterized by a stereotypical macroscopic structure, where the nuclei are densely and heterogeneously packed among different subregions of the hippocampus. Despite the fact that tissue‐specific cellular organization has been implicated in neural function, it has been technically challenging to quantitatively analyze ...
Konstantin Hein, Humberto Romero‐Limon, Conrad Möckel, Anne Karasinsky, Stephanie Möllmert, Jona Kayser, Alessio Zaccone, Jochen Guck, Tomohisa Toda   +8 more
wiley   +1 more source

The Strength of Target Representations Drives Mnemonic Discrimination: Evidence From Extended Delay and Hippocampal Damage

Hippocampus, Volume 36, Issue 6, November 2026.
ABSTRACT Mnemonic discrimination is critical for episodic memory and is dependent on the computational process of pattern separation, which allows the memory system to disambiguate prior memories from potentially overlapping new memories and avoid interference.
C. Brock Kirwan, Samuel P. Chipman, Martina K. Hollearn, Cory S. Inman, Michaela S. Shields, Derin Cobia   +5 more
wiley   +1 more source

Chronic Electroconvulsive Shock Disrupts Hippocampal Physiology and Impairs Associative Memory in Mice

Hippocampus, Volume 36, Issue 6, November 2026.
ABSTRACT Electroconvulsive therapy (ECT) is a highly effective treatment for depression but it has undesirable side effects on various aspects of cognition, including memory. Patients may display retrograde amnesia for autobiographical events and anterograde amnesia in tests of recall and recognition memory. These amnestic effects are likely to depend,
T. R. Zhang, N. P. Vyleta, I. Schwein, B. Askari, M. B. Cooke, F. Vila‐Rodriguez, J. S. Snyder   +6 more
wiley   +1 more source

Harmonized Protocol for Segmentation of the Hippocampal Tail on High‐Resolution In Vivo MRI From the Hippocampal Subfields Group (HSG)

Hippocampus, Volume 36, Issue 6, November 2026.
ABSTRACT The hippocampus is a heterogeneous structure with cytoarchitectonically distinct subfields that exhibit heterogeneous lifespan trajectories and are differentially susceptible to diseases. Advances in high‐resolution imaging have accelerated research on these structures, yet variability in segmentation protocols limits cross‐study comparability.
Robin de Flores, Kelsey L. Canada, Thackery Brown, Nicole J. Gervais, Anne Maass, Gustaf Rådman, Jonathan Shine, Hannah L. Tucker, Eóin N. Molloy, Jenna N. Adams, Michelle Baca Reinke, Arnold Bakker, David Berron, Marshall A. Dalton, Kristen M. Kennedy, Renaud LaJoie, Susanne G. Mueller, Noa Ofen, Rosanna K. Olsen, Naftali Raz, Tracy Riggins, Karen M. Rodrigue, Craig Stark, Lei Wang, Laura E. M. Wisse, Paul A. Yushkevich, Valerie A. Carr, Ana M. Daugherty, the Alzheimer's Disease Neuroimaging Initiative, on behalf of the Hippocampal Subfields Group   +29 more
wiley   +1 more source

Neurodegenerative Diseases: Epidemiology, Risk Factors, Classification, Pathophysiology, Clinical Features, Diagnosis, and Therapeutic Strategies

MedComm, Volume 7, Issue 11, November 2026.
Neurodegenerative diseases share convergent risk architectures and pathological mechanisms, yet diverge in selective vulnerability, clinical presentation, and therapeutic responsiveness. This review integrates cross‐disease epidemiology, pathophysiology, diagnosis, and treatment, highlighting the transition from symptomatic care toward biomarker‐guided
Zimeng He, Jingjing Zeng, Guoqing Wang, Yuxin Li, Feng Zhang   +4 more
wiley   +1 more source