Results 181 to 190 of about 76,364 (261)

High-altitude hypoxia drives dentate gyrus neuronal vulnerability through an IL1α-astrocyte-SLC1A2 pathway. [PDF]

J Neuroinflammation
Zhang Y, Ni Z, Xia T, Zhang N, Shen P, Wang N, Bai Z, Ma Y, Wang R, Sun D, Li S, Huangfu C, Gao Y, Zhou W.   +13 more
europepmc   +1 more source

Impact of O-GlcNAcylation Elevation on Mitophagy and Glia in the Dentate Gyrus. [PDF]

J Neurochem
Kramer J, Fu S, Ouyang X, Rohwer E, Chatham JC, Young ME, Darley-Usmar V, Zhang J.   +7 more
europepmc   +1 more source

Nanoparticles in Vascular Dementia: Advantages and Challenges

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
This review highlights the dual diagnostic and therapeutic potential of nanomaterials in Vascular Dementia (VaD). By effectively crossing the blood–brain barrier, functionalized nanoparticles facilitate early diagnosis by targeting Aβ deposits and vascular lesions.
Xianxin Liu, JiaLi Hu, Yueming qiu, Huaying Wang, Chunxiao Shen, Ziying Liu, Yiting He, Xuefei Du, Xiaorong Zhang   +8 more
wiley   +1 more source

Synaptic plasticity in the perforant pathway drives inhibitory reorganization enhancing dentate gyrus functionality. [PDF]

iScience
Estarellas C, Álvarez-Salvado E, Pérez-Cervera L, Caramés JM, Pérez-Montoyo E, López-Madrona VJ, Garcia-Hernandez R, Mirasso CR, Canals S.   +8 more
europepmc   +1 more source

Long‐lasting remodeling of astrocytes in an Scna1+/− mouse model of Dravet syndrome

Epilepsia, Volume 67, Issue 6, Page 3226-3242, June 2026.
Abstract Objective Dravet syndrome (DS) is a prototypical developmental and epileptic encephalopathy caused by mutations in the SCN1A gene, leading to loss of function of the voltage‐gated sodium channel Naᵥ1.1. The latter causes early onset drug‐resistant seizures and enduring cognitive and behavioral deficits.
Athénaïs Genin, Alicia Janvier, Tristan Moujellil‐Legagneur, Marine Blaquière, Alexis Chaussy, Romane Privé, Fabrice Duprat, Massimo Mantegazza, Etienne Audinat, Nicola Marchi, Noémie Cresto   +10 more
wiley   +1 more source

Context-dependent modulation of LTP and BDNF/TrkB signaling in the dentate gyrus following combined progressive aerobic and rotarod training in male wistar rats. [PDF]

IBRO Neurosci Rep
Sadeghi M, Komaki A, Nazem F.
europepmc   +1 more source

Microelectrode array scaled for human hippocampal slices

Epilepsia Open, Volume 11, Issue 3, Page 777-786, June 2026.
Abstract Objective Temporal lobe epilepsy (TLE) is characterized by recurrent seizures originating usually from the hippocampus, and approximately one‐third of TLE patients remain refractory to pharmacological interventions. Surgical resection offers a potential cure for refractory TLE cases, with approximately 70% achieving seizure freedom. Still, the
Anssi Pelkonen, Vera Lezhneva, Tomi Ryynänen, Joose Kreutzer, Valeriia Sitnikova, Mireia Gómez‐Budia, Adriana Della Pietra, Antonios Dougalis, Jenni Kyyriäinen, Mastaneh Torkamani‐Azar, Henri Eronen, Tuomas Rauramaa, Arto Immonen, Ville Leinonen, Alejandra Sierra, Reetta Kälviäinen, Tarja Malm   +16 more
wiley   +1 more source

A Quantitative Comparison of Medial and Coronal Dentate Gyrus Microdissection Strategies and a Softening-Based Workflow for Reproducible Tissue Procurement. [PDF]

Life (Basel)
Koç T, Öztürk NC.
europepmc   +1 more source

Brain–Computer Interfaces: The Dawn of a New Era in Disease Treatment

Exploration, Volume 6, Issue 3, June 2026.
This study investigates the potential of brain–computer interface (BCI) technology in treating neuropsychiatric disorders, such as movement and communication barriers. Our review examines the history, signal paradigms, and diverse applications of BCI while also discussing ongoing research into novel materials and emerging technologies that offer ...
Yuqi Feng, Wangzheqi Zhang, Jun Chen, Huang Wu, Lei Wu, Yanhao Qiu, Xiaoming Deng, Chenglong Zhu, Yisheng Chen, Zhijie Zhao, Changli Wang, Xiaomin Zhang   +11 more
wiley   +1 more source

In Utero Electroporation Uncovers an Early-Differentiating Subset of Dentate Gyrus Progenitors. [PDF]

Cell Mol Neurobiol
Shinohara HM, Takahashi T.
europepmc   +1 more source