Results 191 to 200 of about 111,284 (274)

Feedback control of excitability and high K+ induced epileptiform bursts in male rat hippocampal slices with a photocaged adenosine A1 receptor agonist

British Journal of Pharmacology, Volume 183, Issue 10, Page 2578-2591, May 2026.
Background and Purpose Adenosine is a potent regulator of neurotransmission and neuronal excitability, through activation of Gi coupled adenosine A1 receptors (A1Rs). Adenosine has gained interest as an anticonvulsant because of its endogenous involvement in ending seizure activity, but peripheral side effects require local application.
Erine Craey, Marijke Vergaelen, Serge Van Calenbergh, Jeroen Spanoghe, Evelien Carrette, Kristl Vonck, Paul Boon, Wytse J. Wadman, Robrecht Raedt   +8 more
wiley   +1 more source

A Quantitative Comparison of Medial and Coronal Dentate Gyrus Microdissection Strategies and a Softening-Based Workflow for Reproducible Tissue Procurement. [PDF]

Life (Basel)
Koç T, Öztürk NC.
europepmc   +1 more source

Hydroxytyrosol Mitigates Anxiety‐Like Behaviors After a Traumatic Experience in Aged Mice in Parallel With Increased Neurogenesis in the Ventral and Dorsal Dentate Gyrus, and Preservation of Gut Microbiota Composition

Journal of Neurochemistry, Volume 170, Issue 5, May 2026.
Hydroxytyrosol (HTyr), a phenolic compound of olive oil, exerts beneficial effects on several age‐related diseases. We previously demonstrated that oral HTyr administration in aging mice enhances hippocampal neurogenesis, known to play a role in memory formation and emotional behaviors. In the present study, we found that HTyr preferentially stimulates
Giorgio D'Andrea, Laura Bertini, Marco Costanzi, Fabiana Canini, Roberta Bernini, Andrea Fochetti, Mariangela Clemente, Silvia Proietti, Manuela Ceccarelli, Carla Caruso, Maurizia Caruso, Ferdinando Scavizzi, Marcello Raspa, Felice Tirone, Laura Micheli   +14 more
wiley   +1 more source

Electroconvulsive Shock Induces Greater Plasticity of Dentate Gyrus Neurons Born in Adulthood Than Those Born in Development. [PDF]

Eur J Neurosci
Zhang TR, Askari B, Smith R, Mallela L, Vila-Rodriguez F, Snyder JS.   +5 more
europepmc   +1 more source

A Review of the Effects of Maternal and Paternal Obesity on Neurodevelopmental Disorders and Related Neurobiology in Rodent and Human Offspring

Obesity Reviews, Volume 27, Issue 5, May 2026.
ABSTRACT Obesity is one of the most prevalent health problems worldwide, and global obesity rates continue to rise. Consequently, rates of obesity in expecting mothers and fathers have also increased. The Developmental Origins of Health and Disease (DOHaD) hypothesis postulates that early‐life exposure to adverse environmental conditions contributes to
Hannah Chadwick, Victorio Bambini Junior, Neil Dawson, Cheryl A. Hawkes   +3 more
wiley   +1 more source

In Utero Electroporation Uncovers an Early-Differentiating Subset of Dentate Gyrus Progenitors. [PDF]

Cell Mol Neurobiol
Shinohara HM, Takahashi T.
europepmc   +1 more source

Maternal Choline Supplementation in a Mouse Model of Down Syndrome and Alzheimer’s Disease Generates Unique Expression Profile Mosaics Within Three Hippocampal Excitatory Neuronal Populations

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Maternal choline supplementation (MCS) is utilized in the Ts65Dn mouse model of Down syndrome (DS) and Alzheimer's disease (AD). At ~6 months of age, laser capture microdissection and single population RNA‐sequencing of three hippocampal neuron populations (CA1 and CA3 pyramidal neurons and dentate gyrus granule cells) were conducted.
Melissa J. Alldred, Kyrillos W. Ibrahim, Harshitha Pidikiti, Sang Han Lee, Adriana Heguy, Gabriela Chiosis, Elliott J. Mufson, Grace E. Stutzmann, Stephen D. Ginsberg   +8 more
wiley   +1 more source

Moderate Exercise Stimulates PACAP-Mediated Neurogenesis in Rat Dentate Gyrus and Cerebellar Cortex. [PDF]

J Funct Morphol Kinesiol
Maugeri G, Di Bartolo S, Palmeri N, D'Amico AG, Brancato D, Federico C, D'Agata V, Musumeci G.   +7 more
europepmc   +1 more source

MSI2 in the dentate gyrus and ovary regulates the reproductive endocrine homeostasis of female mice. [PDF]

Commun Biol
Liu H, Li P, He Y, Yu M, Zhang Z, Li X, Zhu H, Teng B, Fan J, Yin J, Yang W, Hao Q, Chen Y, Li Y, Ren J, Cao G, Liu S, Li H, Du C.   +18 more
europepmc   +1 more source

Median Raphe projection into the dorsal dentate gyrus modulates anxiety behavior and coping with learning under stress. [PDF]

Sci Rep
Quan J, Kriebel M, Anunu R, Snippe-Strauss M, Volkmer H, Richter-Levin G.   +5 more
europepmc   +1 more source