This report contains a gene expression summary of the dentate gyrus (DG), derived from the Allen Brain Atlas (ABA) _in situ_ hybridization mouse data set.
Rachel A. Dalley +3 more
core +5 more sources
The dentate gyrus: fundamental neuroanatomical organization (dentate gyrus for dummies) [PDF]
The dentate gyrus is a simple cortical region that is an integral portion of the larger functional brain system called the hippocampal formation. In this review, the fundamental neuroanatomical organization of the dentate gyrus is described, including ...
Amaral, David G. +5 more
core +5 more sources
Dentate gyrus and hilar region revisited [PDF]
It is suggested that the dentate gyrus and hilar region in the hippocampus perform memory selection and that the selectivity of the gating of memory by this circuit is modulated by the norepinephrine–glutamate loop described by Mather et ...
Houghton, Conor J
core +6 more sources
Regrowing the adult brain: NF-κB controls functional circuit formation and tissue homeostasis in the dentate gyrus. [PDF]
Cognitive decline during aging is correlated with a continuous loss of cells within the brain and especially within the hippocampus, which could be regenerated by adult neurogenesis.
Yvonne Imielski +12 more
doaj +2 more sources
Ethanol neurotoxicity and dentate gyrus development
Maternal alcohol ingestion during pregnancy adversely affects the developing fetus, often leading to fetal alcohol syndrome (FAS). One of the most severe consequences of FAS is brain damage that is manifested as cognitive, learning, and behavioral ...
Wang, Zhi-Yu +10 more
core +6 more sources
Enigmas of the Dentate Gyrus [PDF]
We are rapidly approaching a better understanding of the mechanisms that allow our brains to form distinct representations for similar events or episodes. McHugh et al. have brought that goal one step closer by showing that NMDA receptor-dependent synaptic plasticity in the dentate gyrus is necessary for immediate differentiation between environments ...
Leutgeb, Jill K., Moser, Edvard I.
openaire +2 more sources
A comparative study of the dentate gyrus in hippocampal sclerosis in epilepsy and dementia [PDF]
Hippocampal Sclerosis (HS) is long-recognised in association with epilepsy (HSE ) and more recently in the context of cognitive decline or dementia in the elderly (HSD ), in some cases as a component of neurodegenerative diseases, including Alzheimer's ...
R. Bandopadhyay +11 more
core +2 more sources
Performance on a pattern separation task by Alzheimer's patients shows possible links between disrupted dentate gyrus activity and apolipoprotein E is an element of 4 status and cerebrospinal fluid amyloid-beta 42 levels [PDF]
Introduction: Emerging evidence suggests that decreased adult hippocampal neurogenesis represents an early critical event in the course of Alzheimer's disease (AD).
Annas, Peter +14 more
core +1 more source
Absent or low rate of adult neurogenesis in the hippocampus of bats (Chiroptera) [PDF]
Bats are the only flying mammals and have well developed navigation abilities for 3D-space. Even bats with comparatively small home ranges cover much larger territories than rodents, and long-distance migration by some species is unique among small ...
Winter, Y +23 more
core +2 more sources
The dentate gyrus in depression
Abstract Extensive preclinical research has been conducted in recent years to reveal the cell types, neuronal circuits and molecular and morphological changes implicated in the function of the dentate gyrus in depression. This was profoundly facilitated by the emergence of methods such as gene targeting, neuronal cell activity ...
Gali Umschweif +2 more
openaire +3 more sources

