Results 11 to 20 of about 62,950 (262)

Postnatal changes in glucose transporter 3 expression in the dentate gyrus of the C57BL/6 mouse model

Laboratory Animal Research, 2016
In this study, we observed the ontogenetic changes in glucose transporter 3 (GLUT3) immunoreactivity, a major neuronal GLUT, in the dentate gyrus of mouse brains at various ages: postnatal day (P) 1, 7, 14, 28, and 56.
Hyo Young Jung, Hee Sun Yim, Dae Young Yoo, Jong Whi Kim, Jin Young Chung, Je Kyung Seong, Yeo Sung Yoon, Dae Won Kim, In Koo Hwang   +8 more
doaj   +1 more source

In Vivo and In Vitro Treatment With Edaravone Promotes Proliferation of Neural Progenitor Cells Generated Following Neuronal Loss in the Mouse Dentate Gyrus

Journal of Pharmacological Sciences, 2013
Edaravone is clinically used in Japan for treatment of patients with acute cerebral infarction. To clarify the effect of edaravone on neurogenesis in the hippocampus following neuronal injury in the hippocampal dentate gyrus, we investigated the effect ...
Maho Kikuta, Tatsuo Shiba, Masanori Yoneyama, Koichi Kawada, Taro Yamaguchi, Eiichi Hinoi, Yukio Yoneda, Kiyokazu Ogita   +7 more
doaj   +1 more source

The dentate gyrus: fundamental neuroanatomical organization (dentate gyrus for dummies) [PDF]

, 2007
The dentate gyrus is a simple cortical region that is an integral portion of the larger functional brain system called the hippocampal formation. In this review, the fundamental neuroanatomical organization of the dentate gyrus is described, including principal cell types and their connectivity, and a summary of the major extrinsic inputs of the ...
Amaral David G, Scharfman Helen E, Lavenex Pierre   +2 more
openaire   +3 more sources

Beneficial In Vivo Effect of Aripiprazole on Neuronal Regeneration Following Neuronal Loss in the Dentate Gyrus: Evaluation Using a Mouse Model of Trimethyltin-Induced Neuronal Loss/Self-Repair in the Dentate Gyrus

Journal of Pharmacological Sciences, 2014
.: Aripiprazole is used clinically as an atypical antipsychotic. We evaluated the effect of in vivo treatment with aripiprazole on the proliferation and differentiation of neural stem/progenitor cells in a mouse model, trimethyltin-induced neuronal loss ...
Masanori Yoneyama, Shigeru Hasebe, Noriko Kawamoto, Tatsuo Shiba, Taro Yamaguchi, Maho Kikuta, Makoto Shuto, Kiyokazu Ogita   +7 more
doaj   +1 more source

Status epilepticus induced Gadd45b is required for augmented dentate neurogenesis

Stem Cell Research, 2020
In animal models with temporal lobe epilepsy (TLE), the status epilepticus (SE) leads to a dramatic increase in number of newly born neuron in the subgranular zone (SGZ) of dentate gyrus.
Xin-Li Xiao, Xiao-Lin Wu, Peng-Bo Yang, Hai-Bo Hu, Yu Chen, Min-Li, Kai-Wei Si, Feng Wu, Jian-Xin Liu   +8 more
doaj   +1 more source

The dentate gyrus in depression

European Journal of Neuroscience, 2019
Abstract Extensive preclinical research has been conducted in recent years to reveal the cell types, neuronal circuits and molecular and morphological changes implicated in the function of the dentate gyrus in depression. This was profoundly facilitated by the emergence of methods such as gene targeting, neuronal cell activity ...
Gali Umschweif, Paul Greengard, Yotam Sagi   +2 more
openaire   +3 more sources

Transmembrane protein 108 involves in adult neurogenesis in the hippocampal dentate gyrus

Cell & Bioscience, 2019
Background Transmembrane protein 108 (Tmem108) is a risk gene of psychiatric diseases including schizophrenia, bipolar disorder and major depression disorder. However, the pathophysiological mechanisms of Tmem108 are largely unknown.
Zheng Yu, Dong Lin, Yanzi Zhong, Bin Luo, Shengsheng Liu, Erkang Fei, Xinsheng Lai, Suqi Zou, Shunqi Wang   +8 more
doaj   +1 more source

Decrease in glucose transporter 1 levels and translocation of glucose transporter 3 in the dentate gyrus of C57BL/6 mice and gerbils with aging

Laboratory Animal Research, 2018
In the present study, we compared the cell-specific expression and changes protein levels in the glucose transporters (GLUTs) 1 and 3, the major GLUTs in the mouse and gerbil brains using immuno-histochemistry and Western blot analysis. In both mouse and
Kwon Young Lee, Dae Young Yoo, Hyo Young Jung, Loktam Baek, Hangyul Lee, Hyun Jung Kwon, Jin Young Chung, Seok Hoon Kang, Dae Won Kim, In Koo Hwang, Jung Hoon Choi   +10 more
doaj   +1 more source

Terminal Differentiation of Adult Hippocampal Progenitor Cells Is a Step Functionally Dissociable from Proliferation and Is Controlled by Tis21, Id3 and NeuroD2

Frontiers in Cellular Neuroscience, 2017
Cell proliferation and differentiation are interdependent processes. Here, we have asked to what extent the two processes of neural progenitor cell amplification and differentiation are functionally separated.
Laura Micheli, Manuela Ceccarelli, Roberta Gioia, Giorgio D’Andrea, Stefano Farioli-Vecchioli, Marco Costanzi, Daniele Saraulli, Daniele Saraulli, Vincenzo Cestari, Felice Tirone   +9 more
doaj   +1 more source

Temporal changes in prosaposin expression in the rat dentate gyrus after birth. [PDF]

PLoS ONE, 2014
Neurogenesis in the hippocampal dentate gyrus occurs constitutively throughout postnatal life. Adult neurogenesis includes a multistep process that ends with the formation of a postmitotic and functionally integrated new neuron. During adult neurogenesis,
Midori Morishita, Hiroaki Nabeka, Tetsuya Shimokawa, Kyojy Miyawaki, Takuya Doihara, Shouichiro Saito, Naoto Kobayashi, Seiji Matsuda   +7 more
doaj   +1 more source