Results 21 to 30 of about 72,047 (256)

Beneficial In Vivo Effect of Aripiprazole on Neuronal Regeneration Following Neuronal Loss in the Dentate Gyrus: Evaluation Using a Mouse Model of Trimethyltin-Induced Neuronal Loss/Self-Repair in the Dentate Gyrus

Journal of Pharmacological Sciences, 2014
.: Aripiprazole is used clinically as an atypical antipsychotic. We evaluated the effect of in vivo treatment with aripiprazole on the proliferation and differentiation of neural stem/progenitor cells in a mouse model, trimethyltin-induced neuronal loss ...
Masanori Yoneyama, Shigeru Hasebe, Noriko Kawamoto, Tatsuo Shiba, Taro Yamaguchi, Maho Kikuta, Makoto Shuto, Kiyokazu Ogita   +7 more
doaj   +1 more source

Decrease in glucose transporter 1 levels and translocation of glucose transporter 3 in the dentate gyrus of C57BL/6 mice and gerbils with aging

Laboratory Animal Research, 2018
In the present study, we compared the cell-specific expression and changes protein levels in the glucose transporters (GLUTs) 1 and 3, the major GLUTs in the mouse and gerbil brains using immuno-histochemistry and Western blot analysis. In both mouse and
Kwon Young Lee, Dae Young Yoo, Hyo Young Jung, Loktam Baek, Hangyul Lee, Hyun Jung Kwon, Jin Young Chung, Seok Hoon Kang, Dae Won Kim, In Koo Hwang, Jung Hoon Choi   +10 more
doaj   +1 more source

Terminal Differentiation of Adult Hippocampal Progenitor Cells Is a Step Functionally Dissociable from Proliferation and Is Controlled by Tis21, Id3 and NeuroD2

Frontiers in Cellular Neuroscience, 2017
Cell proliferation and differentiation are interdependent processes. Here, we have asked to what extent the two processes of neural progenitor cell amplification and differentiation are functionally separated.
Laura Micheli, Manuela Ceccarelli, Roberta Gioia, Giorgio D’Andrea, Stefano Farioli-Vecchioli, Marco Costanzi, Daniele Saraulli, Daniele Saraulli, Vincenzo Cestari, Felice Tirone   +9 more
doaj   +1 more source

Combined role of seizure-induced dendritic morphology alterations and spine loss in newborn granule cells with mossy fiber sprouting on the hyperexcitability of a computer model of the dentate gyrus. [PDF]

PLoS Computational Biology, 2014
Temporal lobe epilepsy strongly affects hippocampal dentate gyrus granule cells morphology. These cells exhibit seizure-induced anatomical alterations including mossy fiber sprouting, changes in the apical and basal dendritic tree and suffer substantial ...
Julian Tejada, Norberto Garcia-Cairasco, Antonio C Roque   +2 more
doaj   +1 more source

Postnatal and Adult Neurogenesis in Mammals, Including Marsupials

Cells, 2022
In mammals, neurogenesis occurs during both embryonic and postnatal development. In eutherians, most brain structures develop embryonically; conversely, in marsupials, a number of brain structures develop after birth.
Katarzyna Bartkowska, Beata Tepper, Krzysztof Turlejski, Ruzanna Djavadian   +3 more
doaj   +1 more source

Temporal changes in prosaposin expression in the rat dentate gyrus after birth. [PDF]

PLoS ONE, 2014
Neurogenesis in the hippocampal dentate gyrus occurs constitutively throughout postnatal life. Adult neurogenesis includes a multistep process that ends with the formation of a postmitotic and functionally integrated new neuron. During adult neurogenesis,
Midori Morishita, Hiroaki Nabeka, Tetsuya Shimokawa, Kyojy Miyawaki, Takuya Doihara, Shouichiro Saito, Naoto Kobayashi, Seiji Matsuda   +7 more
doaj   +1 more source

Cultured subventricular zone progenitor cells transduced with neurogenin-2 become mature glutamatergic neurons and integrate into the dentate gyrus. [PDF]

, 2012
We have previously shown that transplantation of immature DCX+/NeuN+/Prox1+ neurons (found in the neonatal DG), but not undifferentiated neuronal progenitor cells (NPCs) from ventral subventricular zone (SVZ), results in neuronal maturation in vivo ...
Xia Chen, Lepier Alexandra, Tolkovsky Aviva M., Alexandra Lepier, Chen, Xia, Aviva M Tolkovsky, Lepier, Alexandra, Chen, X., Berninger, Benedikt, Herbert, Joe, Chen Xia, Herbert Joe, Lepier, A., Tolkovsky, A.M., Berninger Benedikt, Tolkovsky, Aviva M., Benedikt Berninger, Joe Herbert, Berninger, B., Herbert, J.   +19 more
core   +2 more sources

Pemberian Asam Valproat pada Induk Tikus Bunting Menghambat Sintesis Insulin pada Sel Otak Anak Tikus

Majalah Kedokteran Bandung, 2017
Asam valproat memengaruhi aktivitas histone deacetylase yang berperan dalam ekspresi gen selama organogenesis. Insulin berperan dalam proliferasi dan diferensiasi sel-sel saraf dentate gyrus hipokampus.
Komariah Komariah, Bambang Kiranadi, Adi Winanto, Wasmen Manalu, Ekowati Handharyani   +4 more
doaj   +1 more source

Exercise-Induced Activated Platelets Increase Adult Hippocampal Precursor Proliferation and Promote Neuronal Differentiation

Stem Cell Reports, 2019
Summary: Physical activity is a strong positive physiological modulator of adult neurogenesis in the hippocampal dentate gyrus. Although the underlying regulatory mechanisms are still unknown, systemic processes must be involved.
Odette Leiter, Suse Seidemann, Rupert W. Overall, Beáta Ramasz, Nicole Rund, Sonja Schallenberg, Tatyana Grinenko, Ben Wielockx, Gerd Kempermann, Tara L. Walker   +9 more
doaj   +1 more source

Bacopa monnieri extract improves novel object recognition, cell proliferation, neuroblast differentiation, brain-derived neurotrophic factor, and phosphorylation of cAMP response element-binding protein in the dentate gyrus

Laboratory Animal Research, 2018
Bacopa monnieri is a medicinal plant with a long history of use in Ayurveda, especially in the treatment of poor memory and cognitive deficits. In the present study, we hypothesized that Bacopa monnieri extract (BME) can improve memory via increased cell
Hyun Jung Kwon, Hyo Young Jung, Kyu Ri Hahn, Woosuk Kim, Jong Whi Kim, Dae Young Yoo, Yeo Sung Yoon, In Koo Hwang, Dae Won Kim   +8 more
doaj   +1 more source