Results 21 to 30 of about 62,950 (262)

Combined role of seizure-induced dendritic morphology alterations and spine loss in newborn granule cells with mossy fiber sprouting on the hyperexcitability of a computer model of the dentate gyrus. [PDF]

open access: yesPLoS Computational Biology, 2014
Temporal lobe epilepsy strongly affects hippocampal dentate gyrus granule cells morphology. These cells exhibit seizure-induced anatomical alterations including mossy fiber sprouting, changes in the apical and basal dendritic tree and suffer substantial ...
Julian Tejada   +2 more
doaj   +1 more source

Postnatal and Adult Neurogenesis in Mammals, Including Marsupials

open access: yesCells, 2022
In mammals, neurogenesis occurs during both embryonic and postnatal development. In eutherians, most brain structures develop embryonically; conversely, in marsupials, a number of brain structures develop after birth.
Katarzyna Bartkowska   +3 more
doaj   +1 more source

Pemberian Asam Valproat pada Induk Tikus Bunting Menghambat Sintesis Insulin pada Sel Otak Anak Tikus

open access: yesMajalah Kedokteran Bandung, 2017
Asam valproat memengaruhi aktivitas histone deacetylase yang berperan dalam ekspresi gen selama organogenesis. Insulin berperan dalam proliferasi dan diferensiasi sel-sel saraf dentate gyrus hipokampus.
Komariah Komariah   +4 more
doaj   +1 more source

Exercise-Induced Activated Platelets Increase Adult Hippocampal Precursor Proliferation and Promote Neuronal Differentiation

open access: yesStem Cell Reports, 2019
Summary: Physical activity is a strong positive physiological modulator of adult neurogenesis in the hippocampal dentate gyrus. Although the underlying regulatory mechanisms are still unknown, systemic processes must be involved.
Odette Leiter   +9 more
doaj   +1 more source

Bacopa monnieri extract improves novel object recognition, cell proliferation, neuroblast differentiation, brain-derived neurotrophic factor, and phosphorylation of cAMP response element-binding protein in the dentate gyrus

open access: yesLaboratory Animal Research, 2018
Bacopa monnieri is a medicinal plant with a long history of use in Ayurveda, especially in the treatment of poor memory and cognitive deficits. In the present study, we hypothesized that Bacopa monnieri extract (BME) can improve memory via increased cell
Hyun Jung Kwon   +8 more
doaj   +1 more source

Sampling the Mouse Hippocampal Dentate Gyrus [PDF]

open access: yesFrontiers in Neuroanatomy, 2017
ISSN:1662 ...
Lisa Basler   +7 more
openaire   +6 more sources

Contribution of Egr1/Zif268 to activity-dependent Arc/Arg3.1 transcription in the dentate gyrus and area CA1 of the hippocampus

open access: yesFrontiers in Behavioral Neuroscience, 2011
Egr1, a member of the Egr family of transcription factors, and Arc are immediate early genes known to play major roles in synaptic plasticity and memory.
Zsuzsa ePenke   +5 more
doaj   +1 more source

Endocannabinoids in the dentate gyrus [PDF]

open access: yes, 2007
Recent years have produced rapid and enormous growth in our understanding of endocannabinoid-mediated signaling in the CNS. While much of the recent progress has focused on other areas of the brain, a significant body of evidence has developed that indicates the presence of a robust system for endocannabinoid-mediated signaling in the dentate gyrus ...
openaire   +2 more sources

Sex steroids and the dentate gyrus [PDF]

open access: yes, 2007
In the late 1980s, the finding that the dentate gyrus contains more granule cells in the male than in the female of certain mouse strains provided the first indication that the dentate gyrus is a significant target for the effects of sex steroids during development. Gonadal hormones also play a crucial role in shaping the function and morphology of the
Tibor, Hajszan   +2 more
openaire   +2 more sources

Nonrandom Local Circuits in the Dentate Gyrus [PDF]

open access: yesThe Journal of Neuroscience, 2008
The dentate hilus has been extensively studied in relation to its potential role in memory and in temporal lobe epilepsy. Little is known, however, about the synapses formed between the two major cell types in this region, glutamatergic mossy cells and hilar interneurons, or the organization of local circuits involving these cells.
Phillip, Larimer, Ben W, Strowbridge
openaire   +2 more sources

Home - About - Disclaimer - Privacy