Results 31 to 40 of about 116,345 (333)
Modulation of adult-born neurons in the inflamed hippocampus. [PDF]
, 2013 Throughout life new neurons are continuously added to the hippocampal circuitry involved with spatial learning and memory. These new cells originate from neural precursors in the subgranular zone of the dentate gyrus, migrate into the granule cell layer,
Belarbi, Karim, Rosi, Susanna
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Stem Cell Reports, 2019 Summary: Physical activity is a strong positive physiological modulator of adult neurogenesis in the hippocampal dentate gyrus. Although the underlying regulatory mechanisms are still unknown, systemic processes must be involved.
Odette Leiter +9 more
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Sampling the Mouse Hippocampal Dentate Gyrus [PDF]
Frontiers in Neuroanatomy, 2017 ISSN:1662 ...
Lisa Basler +7 more
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Frontiers in Behavioral Neuroscience, 2011 Egr1, a member of the Egr family of transcription factors, and Arc are immediate early genes known to play major roles in synaptic plasticity and memory.
Zsuzsa ePenke +5 more
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Mnemonic discrimination relates to perforant path integrity: An ultra-high resolution diffusion tensor imaging study. [PDF]
, 2016 Pattern separation describes the orthogonalization of similar inputs into unique, non-overlapping representations. This computational process is thought to serve memory by reducing interference and to be mediated by the dentate gyrus of the hippocampus ...
Bennett, Ilana J, Stark, Craig EL
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Endocannabinoids in the dentate gyrus [PDF]
, 2007 Recent years have produced rapid and enormous growth in our understanding of endocannabinoid-mediated signaling in the CNS. While much of the recent progress has focused on other areas of the brain, a significant body of evidence has developed that indicates the presence of a robust system for endocannabinoid-mediated signaling in the dentate gyrus ...
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Sex steroids and the dentate gyrus [PDF]
, 2007 In the late 1980s, the finding that the dentate gyrus contains more granule cells in the male than in the female of certain mouse strains provided the first indication that the dentate gyrus is a significant target for the effects of sex steroids during development. Gonadal hormones also play a crucial role in shaping the function and morphology of the
Tibor, Hajszan +2 more
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Nonrandom Local Circuits in the Dentate Gyrus [PDF]
The Journal of Neuroscience, 2008 The dentate hilus has been extensively studied in relation to its potential role in memory and in temporal lobe epilepsy. Little is known, however, about the synapses formed between the two major cell types in this region, glutamatergic mossy cells and hilar interneurons, or the organization of local circuits involving these cells.
Phillip, Larimer, Ben W, Strowbridge
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Microglia and neurogenesis in the epileptic dentate gyrus [PDF]
Neurogenesis, 2016 Microglia are recognized as major immune cells in the brain. They have been traditionally studied in various contexts of disease, where their activation has been assumed to induce mostly detrimental effects. Recent studies, however, have challenged the current view of microglia, clarifying their essential contribution to the development of neural ...
Cong, Luo, Yuji, Ikegaya, Ryuta, Koyama
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How informative are spatial CA3 representations established by the dentate gyrus? [PDF]
, 2009 In the mammalian hippocampus, the dentate gyrus (DG) is characterized by sparse and powerful unidirectional projections to CA3 pyramidal cells, the so-called mossy fibers. Mossy fiber synapses appear to duplicate, in terms of the information they convey,
Cerasti, Erika, Treves, Alessandro
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