Alteration of dentate gyrus astrocytes in diabetic rats: Protective role of Urtica dioica [PDF]
, 2011 Diabetes mellitus can cause astrocytes alterations in the central nervous system. Urtica dioica (Nettle) is among several species listed for their use against diabetes in folk medicine.
Ghafari, S. +3 more
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Morris Water Maze Learning in Two Rat Strains Increases the Expression of the Polysialylated Form of the Neural Cell Adhesion Molecule in the Dentate Gyrus But Has No Effect on Hippocampal Neurogenesis [PDF]
, 2005 In the current study, the authors investigated whether Morris water maze learning induces alterations in hippocampal neurogenesis or neural cell adhesion molecule (NCAM) polysialylation in the dentate gyrus.
Borght, Karin van der, +4 more
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Extended Interneuronal Network of the Dentate Gyrus [PDF]
Cell Reports, 2017 Local interneurons control principal cells within individual brain areas, but anecdotal observations indicate that interneuronal axons sometimes extend beyond strict anatomical boundaries. Here, we use the case of the dentate gyrus (DG) to show that boundary-crossing interneurons with cell bodies in CA3 and CA1 constitute a numerically significant and ...
Ivan Soltesz +5 more
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Inhibitory Gatin in Dentate Gyrus
, 2021 Trabajo presentado en la 30th Annual Computational Neuroscience Meeting (CNS*2021), celebrada online del 3 al 7 de julio de 2021.
Estarellas, Cristian +2 more
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Dentate gyrus and spatial behaviour
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2009 This article reviews evidence from studies employing colchicine-induced granule cell loss in the adult rat brain, and irradiation-induced hypoplasia of the neonatal dentate gyrus, on the performance of spatial and non-spatial behavioral tasks. The general picture emerging from this analysis reveals that the dentate gyrus granule cells are critically ...
Gilberto Fernando Xavier +1 more
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Frontiers in Behavioral Neuroscience, 2011 Egr1, a member of the Egr family of transcription factors, and Arc are immediate early genes known to play major roles in synaptic plasticity and memory.
Zsuzsa ePenke +5 more
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Neuroprotective efficacy of P7C3 compounds in primate hippocampus. [PDF]
, 2018 There is a critical need for translating basic science discoveries into new therapeutics for patients suffering from difficult to treat neuropsychiatric and neurodegenerative conditions.
Bauman, Melissa D +8 more
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The N-methyl-d-aspartate receptor antagonist CPP alters synapse and spine structure and impairs long-term potentiation and long-term depression induced morphological plasticity in dentate gyrus of the awake rat [PDF]
, 2010 Long-term morphological synaptic changes associated with homosynaptic long-term potentiation (LTP) and heterosynaptic long-term depression (LTD) in vivo, in awake adult rats were analyzed using three-dimensional (3-D) reconstructions of electron ...
Abraham +61 more
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Evolution of the mammalian dentate gyrus [PDF]
Journal of Comparative Neurology, 2015 ABSTRACTThe dentate gyrus (DG), a part of the hippocampal formation, has important functions in learning, memory, and adult neurogenesis. Compared with homologous areas in sauropsids (birds and reptiles), the mammalian DG is larger and exhibits qualitatively different phenotypes: 1) folded (C‐ or V‐shaped) granule neuron layer, concave toward the hilus
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Granule Cell Dispersion in Human Temporal Lobe Epilepsy: Proteomics investigation of neurodevelopmental migratory pathways [PDF]
, 2020 Granule cell dispersion (GCD) is a common pathological feature observed in the hippocampus of patients with Mesial Temporal Lobe Epilepsy (MTLE). Pathomechanisms underlying GCD remain to be elucidated, but one hypothesis proposes aberrant reactivation of
Al-Kaaby, B. +11 more
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