Results 31 to 40 of about 61,176 (239)
Dentate gyrus and spatial behaviour
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2009 This article reviews evidence from studies employing colchicine-induced granule cell loss in the adult rat brain, and irradiation-induced hypoplasia of the neonatal dentate gyrus, on the performance of spatial and non-spatial behavioral tasks. The general picture emerging from this analysis reveals that the dentate gyrus granule cells are critically ...
Gilberto Fernando Xavier +1 more
openaire +3 more sources
How informative are spatial CA3 representations established by the dentate gyrus? [PDF]
, 2009 In the mammalian hippocampus, the dentate gyrus (DG) is characterized by sparse and powerful unidirectional projections to CA3 pyramidal cells, the so-called mossy fibers. Mossy fiber synapses appear to duplicate, in terms of the information they convey, what CA3 cells already receive from entorhinal cortex layer II cells, which project both to the ...
arxiv +1 more source
Population and Individual Firing Behaviors in Sparsely Synchronized Rhythms in The Hippocampal Dentate Gyrus [PDF]
arXiv, 2021 We investigate population and individual firing behaviors in sparsely synchronized rhythms (SSRs) in a spiking neural network of the hippocampal dentate gyrus (DG). The main encoding granule cells (GCs) are grouped into lamellar clusters. In each GC cluster, there is one inhibitory (I) basket cell (BC) along with excitatory (E) GCs, and they form the E-
arxiv
Inhibitory Gatin in Dentate Gyrus
, 2021 Trabajo presentado en la 30th Annual Computational Neuroscience Meeting (CNS*2021), celebrada online del 3 al 7 de julio de 2021.
Estarellas, Cristian +2 more
openaire +3 more sources
Disynaptic Effect of Hilar Cells on Pattern Separation in A Spiking Neural Network of Hippocampal Dentate Gyrus [PDF]
arXiv, 2021 We investigate disynaptic effect of the hilar cells on pattern separation in a spiking neural network of the hippocampal dentate gyrus (DG). The principal granule cells (GCs) in the DG perform pattern separation, transforming similar input patterns into less-similar output patterns. The hilus consists of excitatory mossy cells (MCs) and inhibitory HIPP
arxiv
Modelling hippocampal neurogenesis across the lifespan in seven species [PDF]
, 2011 The aim of this study was to estimate the number of new cells and neurons added to the dentate gyrus across the lifespan, and to compare the rate of age-associated decline in neurogenesis across species. Data from mice (Mus musculus), rats (Rattus norvegicus), lesser hedgehog tenrecs (Echinops telfairi), macaques (Macaca mulatta), marmosets (Callithrix
arxiv +1 more source
Effect of Adult-Born Immature Granule Cells on Pattern Separation in The Hippocampal Dentate Gyrus [PDF]
arXiv, 2023 Young immature granule cells (imGCs) appear via adult neurogenesis in the hippocampal dentate gyrus (DG). In comparison to mature GCs (mGCs) (born during development), the imGCs exhibit two competing distinct properties such as high excitability and low excitatory innervation. We develop a spiking neural network for the DG, incorporating the imGCs, and
arxiv
Frontiers in Behavioral Neuroscience, 2011 Egr1, a member of the Egr family of transcription factors, and Arc are immediate early genes known to play major roles in synaptic plasticity and memory.
Zsuzsa ePenke +5 more
doaj +1 more source
An atlas of the heterogeneous viscoelastic brain with local power-law attenuation synthesised using Prony-series [PDF]
arXiv, 2023 This review addresses the acute need to acknowledge the mechanical heterogeneity of brain matter and to accurately calibrate its local viscoelastic material properties accordingly. Specifically, it is important to compile the existing and disparate literature on attenuation power laws and dispersion to make progress in wave physics of brain matter, a ...
arxiv
Evolution of the mammalian dentate gyrus [PDF]
Journal of Comparative Neurology, 2015 ABSTRACTThe dentate gyrus (DG), a part of the hippocampal formation, has important functions in learning, memory, and adult neurogenesis. Compared with homologous areas in sauropsids (birds and reptiles), the mammalian DG is larger and exhibits qualitatively different phenotypes: 1) folded (C‐ or V‐shaped) granule neuron layer, concave toward the hilus
openaire +3 more sources