Results 231 to 240 of about 55,224 (274)

5'-Substituted 2'-Deoxycytidines as Non-Substrate Inhibitors of Human Deoxycytidine Kinase

Nucleosides, Nucleotides and Nucleic Acids, 1995
Abstract Several 5′-substituted analogues of 2′-deoxycytidine (dC), including 5′-amino2′,5′-dideoxycytidine (5′-amino-ddC), 5′-azido-2′,5′-dideoxycytidine (5′-azido-ddC) and 5′-O-ethyl-2′-deoxycytidine (5′-O-ethyl-dC), are non-substrate inhibitors of human dC kinase.
K. Krawiec, B. Kierdaszuk, D. Shugar
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5-Ethyl-2'-deoxycytidine, C11H17N3O4

Acta Crystallographica Section C Crystal Structure Communications, 1995
The deoxyribose ring in the title compound adopts the twist conformation ( 3 2 T) with a glycosyl torsion angle of 231.0 (6)°. The pseudo-rotation parameters are P = 180.29 (5)° and τ m = 38.3 (5)°. The exocyclic side chain at C5' has the t conformation [γ = 174.8(11)°].
S. Napper, A. L. Stuart, S. V. P. Kumar, V. S. Gupta, L. T. J. Delbaere   +4 more
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Theoretical analysis of deoxycytidine‐5′‐phosphate protonation

Biopolymers, 1990
AbstractThe electron density distribution in deoxycytidine‐5′‐monophosphate (5′‐dCMP) molecule and dianion has been studied by the method of CNDO/2. The comparison between the results of calculation for the neutral molecule and the data obtained by Pearlman and Kim13 shows that there is a linear correlation between the atomic charges calculated using ...
E B, Starikov, Y F, Pedash
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Selective activation of deoxycytidine kinase by thymidine-5′-thiosulphate and release by deoxycytidine in human lymphocytes

Biochemical Pharmacology, 2003
Deoxycytidine kinase (dCK) catalyses the rate-limiting step of the salvage of three natural deoxyribonucleosides as well as several therapeutic nucleoside analogues, which in turn can enhance its enzymatic activity [Biochem Pharmacol 56 (1998) 1175], improving the efficacy of the cytostatic therapy.
Gergely, Keszler, Karoly, Szikla, Zygmunt, Kazimierczuk, Tatjana, Spasokoukotskaja, Maria, Sasvari-Szekely, Maria, Staub   +5 more
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Structure of 5-methyl-2'-deoxycytidine

Acta Crystallographica Section C Crystal Structure Communications, 1988
C10H15N3O4, Mr = 241.2, orthorhombic, P2(1)2(1)2(1), a = 10.454 (1), b = 11.922 (1), c = 9.057 (1) A, V = 1128.9 (1) A3, Z = 4, D chi = 1.419 Mg m-3, Cu K alpha radiation, lambda = 1.54178 A, mu = 0.95 mm-1, F(000) = 512, room temperature, R = 0.029 for 1186 observed reflections.
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Phosphorylation of 5-Halogenated Deoxycytidine Analogues by Deoxycytidine Kinase

Molecular Pharmacology, 1973
G M, Cooper, S, Greer
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Deoxycytidine: a morphine antagonist.

Archives internationales de pharmacodynamie et de therapie, 1978
Deoxycytidine antagonizes the analgesic action of morphine in the rat, morphine-induced respiratory depression in the rabbit and mitigates withdrawal in the dependent mouse. Administration of deoxycytidine does not precipitate the abstinence syndrome in dependent mice, a property shared by certain other endogenous morphine antagonsits.
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Deoxycytidine Triphosphate

2021
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Quinone Methide Alkylation of Deoxycytidine

The Journal of Organic Chemistry, 1997
Steven E., Rokita, Jianhong, Yang, Praveen, Pande, William A., Greenberg   +3 more
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Deoxycytidine kinase

1997
Dietmar Schomburg, Dörte Stephan
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