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Encyclopedia, 2021 The deoxyribonuclease 1 (Dnase1) family is a key family of endonucleases that degrades DNA. Loss of Dnase1 family function causes several diseases where the host’s immune system targets the host, such as systemic lupus erythematosus, hypocomplementemic ...
Minal Engavale +6 more
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Deoxyribonucleases of Pneumococcus
Journal of Biological Chemistry, 1967 Abstract Two enzymes with deoxyribonuclease activity were isolated from Pneumococcus. One of these, an endonuclease active on both native and denatured deoxyribonucleic acid, produced 5'-phosphate-terminated fragments which, even after extensive degradation, were larger than mononucleotides.
Sanford A. Lacks, Bill Greenberg
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The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
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Extracellular Deoxyribonuclease Production by Yeasts [PDF]
Journal of Bacteriology, 1969 A total of 20 genera of yeasts and yeastlike organisms were tested for their ability to produce an extracellular deoxyribonuclease. Results indicate that ability to produce the enzyme appears to be a specific characteristic of the three genera Rhodotorula, Cryptococcus , and Tremella .
John Cazin +3 more
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Bronchopleural communication following intrapleural doses of tPA/DNase for empyema
Respirology Case Reports, 2020 Intrapleural tissue plasminogen activator (tPA) and deoxyribonuclease (DNase) therapy is a new treatment for pleural infection. Clinical experiences of tPA/DNase therapy, and its complications, are cumulating.
Bapti Roy +3 more
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Pharmacological Activation of cGAS for Cancer Immunotherapy
Frontiers in Immunology, 2021 When compartmentally mislocalized within cells, nucleic acids can be exceptionally immunostimulatory and can even trigger the immune-mediated elimination of cancer.
Kyle M. Garland +15 more
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Deoxyribonuclease activities of rumen bacteria from the genus Prevotella
Acta Agriculturae Slovenica, 1999 Twenty-nine strains belonging to four species of the anaerobic bacterial genus Prevotella were tested for deoxyribonuclease activity against the nonmethylated l phage DNA and circular plasmid pBR322 DNA.
Tomaž ACCETTO, Gorazd AVGUŠTIN
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Detection of some virulence factors in Pseudomonas aeruginosa associated with diarrhea in Kirkuk City [PDF]
Kirkuk Journal of Science, 2015 Background: studies have shown that Pseudomonas aeruginosa can be a potential cause of antibiotic associated diarrhea. Pathogenesis based on endotoxin, exotoxins, and enzymes.
Siham Sh. AL-Salihi, Abbas Y. Hasan
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Antioxidants, 2023 Infection with SARS-CoV-2 during pregnancy increases the risk of pregnancy complications associated with inflammation, which could lead to oxidative stress in the placenta. Whether vaccination against COVID-19 has any effect is unclear.
Kristína Macáková +5 more
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Lipid peroxidation is a nonparenchymal cell event with reperfusion after prolonged liver ischemia [PDF]
, 1990 A proposed mechanism for irreversible ischemic liver damage has been peroxidation of membrane phospholipids by free radicals. However, the hepatocyte is laden with enzymes which are antioxidants and, therefore, ought to be relatively resistant to ...
Makowka, L +3 more
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