Results 41 to 50 of about 202,925 (206)

Extraction and purification of bovine pancreatic Deoxyribonuclease I

open access: yesمجلة مركز بحوث التقنيات الاحيائية, 2010
Samples of bovine pancreatic and calf thymus glands were collected from local slaughterers to extract deoxyribonuclease I enzyme (DNase I) and DNA respectively.
Baidaa S. Hermiz   +2 more
doaj   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

open access: yesAdvanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian   +5 more
wiley   +1 more source

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

open access: yesAdvanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan   +20 more
wiley   +1 more source

Plasma DNA and deoxyribonuclease are associated with glucose metabolism in healthy mice.

open access: yesPLoS ONE, 2022
It is currently unknown why obesity leads in some patients to prediabetes and metabolic syndrome. Microinflammation potentially caused by extracellular DNA is supposed to be involved.
Katarína Kmeťová   +5 more
doaj   +1 more source

A Novel Deoxyribonuclease Low-Molecular-Weight Bacteriocin, Carocin S4, from Pectobacterium carotovorum subsp. carotovorum

open access: yesMicroorganisms, 2023
Pectobacterium carotovorum subsp. carotovorum (Pcc) is known to produce different types of bacteriocins, active protein substances that inhibit or kill related strains and are known to be induced by several factors. In this paper, we report the discovery,
Huang-Pin Wu   +4 more
doaj   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

open access: yesAdvanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li   +7 more
wiley   +1 more source

The process of infection with bacteriophage phiX174, XXII. Synthesis of progeny single-stranded DNA [PDF]

open access: yes, 1968
In a previous article,(1) it was demonstrated that of the labeled thymidine incorporated into the replicative form (RF) of phiX-DNA during the period of RF replication (3-12 or 15 min after infection), approximately half was transferred to virus during ...
Knippers, Rolf   +2 more
core  

Preparation of nuclear matrices from cultured cells: subfractionation of nuclei in situ [PDF]

open access: yes, 1984
Analyses of the different structural systems of the nucleus and the proteins associated with them pose many problems. Because these systems are largely overlapping, in situ localization studies that preserve the in vivo location of proteins and cellular ...
Deppert, Wolfgang, Staufenbiel, Matthias
core   +2 more sources

Back Again to the Future: A New Era for Cerebroprotection

open access: yesAnnals of Neurology, EarlyView.
Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley   +1 more source

A Molecular Dynamics Simulation Study of the Arg206Cys Variant in DNASE1L3 Enzyme

open access: yesBiology and Life Sciences Forum, 2022
Genome-wide association studies (GWAS) have identified that one of the autoimmune disease-associated loci, predisposing for the development of Systemic Lupus Erythematosus (SLE), Rheumatoid Arthritis (RA) and Systemic Sclerosis (SSc), is the rs35677470 ...
Manio Skarlatou   +3 more
doaj   +1 more source

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