Results 51 to 60 of about 101,166 (300)
Preparation of nuclear matrices from cultured cells: subfractionation of nuclei in situ [PDF]
, 1984 Analyses of the different structural systems of the nucleus and the proteins associated with them pose many problems. Because these systems are largely overlapping, in situ localization studies that preserve the in vivo location of proteins and cellular ...
Deppert, Wolfgang, Staufenbiel, Matthias
core +2 more sources
Effect of deoxyribonuclease I treatment for dementia in end-stage Alzheimer’s disease: a case report
Journal of Medical Case Reports, 2016 BackgroundAlzheimer's disease is the most common cause of dementia and is characterized by a progressive loss of brain tissue leading to amyloid-β accumulation and severe decline in cognitive function.
V. Tetz, G. Tetz
semanticscholar +1 more source
Extraction and purification of bovine pancreatic Deoxyribonuclease I
مجلة مركز بحوث التقنيات الاحيائية, 2010 Samples of bovine pancreatic and calf thymus glands were collected from local slaughterers to extract deoxyribonuclease I enzyme (DNase I) and DNA respectively.
Baidaa S. Hermiz +2 more
doaj +1 more source
npj Biofilms and Microbiomes, 2022 Extracellular DNA (eDNA) is a key component of many microbial biofilms including dental plaque. However, the roles of extracellular deoxyribonuclease (DNase) enzymes within biofilms are poorly understood.
Nadia Rostami +11 more
doaj +1 more source
A novel role for synaptic acetylcholinesterase as an apoptotic deoxyribonuclease
Cell Discovery, 2015 In addition to terminating neurotransmission by hydrolyzing acetylcholine, synaptic acetylcholinesterase (AChES) has been found to have a pro-apoptotic role. However, the underlying mechanism has rarely been investigated.
Aiying Du +10 more
semanticscholar +1 more source
Transcript Identification Using Arrayed Hydrogels With TrapFISH
Advanced Materials Technologies, EarlyView.TrapFISH is a novel method for high‐throughput single‐cell transcriptomics. It embeds cells in hyaluronic acid hydrogel beads and uses probe hybridization to quantify custom gene panels. By arraying hydrogels in microfluidic devices, cell barcoding is removed, enhancing scalability for studying cellular heterogeneity and rare cell states by targeting ...
David B. Morse +5 more
wiley +1 more source
Plasma DNA and deoxyribonuclease are associated with glucose metabolism in healthy mice.
PLoS ONE, 2022 It is currently unknown why obesity leads in some patients to prediabetes and metabolic syndrome. Microinflammation potentially caused by extracellular DNA is supposed to be involved.
Katarína Kmeťová +5 more
doaj +1 more source
Deoxyribonuclease Activity in Human Sperm [PDF]
Archives of Andrology, 1985 A previous failure to detect DNase activity in human sperm sonicates was ascribed to an inadequate amount of sperm used. In the present work aliquots contained more sperm (1.5-2.5/10(6)), permitting the detection of enzyme activity. The latter was significantly higher in spermatozoa of oligozoospermic origin compared with activity in normospermic ...
Rina Singer +5 more
openaire +3 more sources
Type I Interferon Signaling Augments Autoimmunity in Neuromyelitis Optica Spectrum Disorder
Advanced Science, EarlyView.The cGAS‐STING innate immune pathway is excessively activated both in peripheral monocytes and CNS microglia in patients with NMOSD, leading to an overproduction of IFN‐I. IFN‐I subsequently acts on AQP4‐specific autoreactive T cells. Blocking this pathway may offer novel therapeutic options for individuals with NMOSD.
Tian‐Xiang Zhang +13 more
wiley +1 more source
The process of infection with bacteriophage phiX174, XXII. Synthesis of progeny single-stranded DNA [PDF]
, 1968 In a previous article,(1) it was demonstrated that of the labeled thymidine incorporated into the replicative form (RF) of phiX-DNA during the period of RF replication (3-12 or 15 min after infection), approximately half was transferred to virus during ...
Knippers, Rolf +2 more
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