Results 91 to 100 of about 14,183,395 (235)

Inhalable Artificial Polymeric Nucleases Degrading Neutrophil Extracellular Trap‐DNAs and Alleviating Pulmonary Fibrosis

Advanced Science, Volume 12, Issue 34, September 11, 2025.
Pulmonary fibrosis (PF) is promoted by NETs that induce fibroblast activation. PEG‐PIm, a polymeric artificial DNase is reported that efficiently degrades NET‐DNA via phosphodiester bond hydrolysis. Inhalation of PEG‐PIm in a mouse PF model prevents fibroblast activation and fibrosis progression, offering a promising therapeutic strategy for NET ...
Yibo Du, Chenxu Zhu, Ruifeng Wang, Shi Chen, Chuang Li, Defang OuYang, Lixin Liu, Yongming Chen   +7 more
wiley   +1 more source

Extracellular Vesicle‐Like Nanoparticles Present in Fermented Botanical Products Suppress Fat Absorption in the Gut

Journal of Food Science, Volume 90, Issue 9, September 2025.
ABSTRACT The fermented botanical product (FBP) is a complex, primarily plant‐based fermented food that has been popular among consumers for many years. Although FBP may modulate gastrointestinal function, the responsible factors and precise mechanisms remain unclear and speculative.
Kotomi Chikama, Koutarou Terada, Chika Yamamoto, Mana Yamamoto, Ayano Hojo, Kotaro Fujioka, Hideto Torii, Lee Wah Lim, Hiroshi Takemori   +8 more
wiley   +1 more source

Herpes simplex virus‐1 infection alters microtubule‐associated protein Tau splicing and promotes Tau pathology in neural models of Alzheimer's disease

Brain Pathology, Volume 35, Issue 5, September 2025.
HSV‐1 infection alters MAPT splicing and promotes Tau pathology in neural models of Alzheimer's disease. HSV‐1 infection in brain organoids and neuronal models increase 4R‐MAPT splicing and Tau hyperphosphorylation. HSV‐1 ICP27 is both necessary and sufficient for inducing these changes highlighting the potential role of HSV‐1 in Alzheimer's disease ...
Emmanuel C. Ijezie, Michael J. Miller, Celine Hardy, Ava R. Jarvis, Timothy F. Czajka, Lianna D'Brant, Natasha Rugenstein, Adam Waickman, Eain Murphy, David C. Butler   +9 more
wiley   +1 more source

The Biology of the Cytolethal Distending Toxins

Toxins, 2011
The cytolethal distending toxins (CDTs), produced by a variety of Gram-negative pathogenic bacteria, are the first bacterial genotoxins described, since they cause DNA damage in the target cells. CDT is an A-B2 toxin, where the CdtA and CdtC subunits are
Teresa Frisan, Ximena Cortes-Bratti, Riccardo Guidi, Lina Guerra   +3 more
doaj   +1 more source

Purification and characterization of deoxyribonuclease from small intestine of camel Camelus dromedarius

Journal of Genetic Engineering and Biotechnology, 2017
The chromatography of deoxyribonuclease (DNase) from small intestine of camel Camelus dromedarius by DEAE-Sepharose separated three isoforms DNase 1, DNase 2 and DNase 3. The DNase 3 was purified to homogeneity by chromatography on Sephacryl S-200.
Somia S. Abdel-Gany, Mohamed O. El-Badry, Afaf S. Fahmy, Saleh A. Mohamed   +3 more
doaj   +1 more source

Correction: A fluorescent biosensor for cardiac biomarker myoglobin detection based on carbon dots and deoxyribonuclease I-aided target recycling signal amplification. [PDF]

RSC Adv, 2022
Chen J, Ran F, Chen Q, Luo D, Ma W, Han T, Wang C, Wang C.   +7 more
europepmc   +1 more source

Studies of the Specificity of Deoxyribonuclease I

, 1961
Steve Vanecko, M. Laskowski
openalex   +2 more sources

A coupled transcription—translation system derived from Escherichia coli: The use of immobilized deoxyribonuclease to eliminate endogenous DNA [PDF]

, 1976
Antoon F.M. Moorman, Ferry Lamie, Leslie A. Grivell   +2 more
openalex   +1 more source

Extracellular manganese-stimulated deoxyribonuclease as a marker event in sporulation of Bacillus subtilis [PDF]

, 1978
A. Akrigg, J. Mandelstam
openalex   +1 more source

Toxinogeny in Corynebacterium diphtheriae After Loss of Catalase, Cystinase, or Deoxyribonuclease Activity [PDF]

, 1973
Neal B. Groman, Cynthia K. Dean
openalex   +1 more source