Results 81 to 90 of about 81,856 (291)

Case series: Clinical response of ketamine infusion in patients with treatment-resistant depression

open access: yesTelangana Journal of Psychiatry
Treatment-resistant depression (TRD) is one of the most debilitating conditions that does not respond to conventional pharmacotherapy. Ketamine is a recently used effective treatment option in depressive disorders with a novel mechanism of action. Still,
Pallavi Preetinanda   +6 more
doaj   +1 more source

Mindfulness-based interventions for anxiety and depression [PDF]

open access: yes, 2017
Published in final edited form as: Psychiatr Clin North Am. 2017 December ; 40(4): 739–749. doi:10.1016/j.psc.2017.08.008.This article reviews the ways in which mindfulness practices have contributed to cognitive and behavioral treatments for depression ...
Gomez, Angelina F., Hofmann, Stefan G.
core   +1 more source

Three‐Dimensional Hierarchical Nanowire‐Networks with Deep‐Focus Tolerance and Adhesion Robustness for Harsh‐Environment SERS Sensing

open access: yesAdvanced Functional Materials, EarlyView.
A 3D nanowire‐network SERS substrate with robust adhesion is developed, featuring pronounced z‐direction optical activity, ultralow detection limit (1.5 × 10−13 M), and excellent signal uniformity (RSD < 10%). Enabled by enhanced light scattering, increased optical density of states, and structural reinforcement, the substrate demonstrates stable, high‐
Jinglai Duan   +6 more
wiley   +1 more source

Risperidone Augmentation in Antidepressant-Resistant Somatic Symptom Disorder

open access: yesPsychiatry and Clinical Psychopharmacology
Chronic somatic symptoms are hallmarks of somatic symptom disorder (SSD), characterized by notable disruptions in the day to day lives of affected patients.
Eun Hyun Seo   +2 more
doaj   +1 more source

Efficacy of repetitive transcranial magnetic stimulation in treatment-resistant depression: the evidence thus far

open access: yesGeneral Psychiatry, 2019
Depression is a common mental disorder, which attributes to significant morbidity, disability and burden of care. A significant number of patients with depression still remain symptomatic after adequate trials of antidepressant treatment as well as ...
Aditya Somani, Sujita Kumar Kar
doaj   +1 more source

Failure of hippocampal deactivation during loss events in treatment-resistant depression [PDF]

open access: yes, 2015
Major depressive disorder is characterized by anhedonia, cognitive biases, ruminations, hopelessness and increased anxiety. Blunted responses to rewards have been reported in a number of recent neuroimaging and behavioural studies of major depressive ...
Blair A. Johnston   +8 more
core   +2 more sources

Designing Asymmetric Memristive Behavior in Proton Mixed Conductors for Neuromorphic Applications

open access: yesAdvanced Functional Materials, EarlyView.
Protonic devices that couple ionic and electronic transport are demonstrated as bioinspired neuromorphic elements. The devices exhibit rubber‐like asymmetric memristive behavior with slow voltage‐driven conductance increase and rapid relaxation, enabling simplified read–write operation.
Nada H. A. Besisa   +6 more
wiley   +1 more source

A new therapy modality for treatment-resistant depression: Vagal nerve stimulation

open access: yesPsychiatry and Behavioral Sciences, 2014
Objective: Although new treatment modalities are recommended for the treatment resistant depression, it has been estimated that some depressive episodes treated for an adequate duration with recommended dose of an antidepressant exhibit treatment ...
Visal Buturak, Bulent Bakar
doaj   +1 more source

Levothyroxine effects on depressive symptoms and limbic glucose metabolism in bipolar disorder: a randomized, placebo-controlled positron emission tomography study. [PDF]

open access: yes, 2016
Adding supraphysiologic doses of levothyroxine (L-T4) to standard treatment for bipolar depression shows promise, but the mechanisms underlying clinical improvement are unknown.
Adli, M   +9 more
core  

Restoration of Sp4 in Forebrain GABAergic Neurons Rescues Hypersensitivity to Ketamine in Sp4 Hypomorphic Mice. [PDF]

open access: yes, 2015
BackgroundKetamine produces schizophrenia-like behavioral phenotypes in healthy people. Prolonged ketamine effects and exacerbation of symptoms after the administration of ketamine have been observed in patients with schizophrenia.
Buell, Mahalah R   +7 more
core   +1 more source

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