Results 131 to 140 of about 9,955 (253)

Isolation and Total Synthesis of PM170453, a New Cyclic Depsipeptide Isolated from Lyngbya sp.

Marine Drugs
In our continuing search for biologically active new chemical entities from marine organisms, we have isolated a new cyclic depsipeptide, PM170453 (1), from a cyanobacterium of the genus Lyngbya sp., collected in the Indo-Pacific Ocean.
Rogelio Fernández, Marta Pérez, Alejandro Losada, Silvia Reboredo, Asier Gómez-San Juan, María Jesús Martín, Andrés Francesch, Simon Munt, Carmen Cuevas   +8 more
doaj   +1 more source

Total Synthesis and Cytotoxicity Studies of a Cyclic Depsipeptide with Proposed Structure of Palau'amide

, 2016
Total synthesis of a cyclic depsipeptide with proposed structure of palau'amide is achieved, which features a stereoselective elaboration of its 5,7-dihydroxy-2,6-dimethyldodec-2-en-11-ynoic acid unit.
Bin Zou (539731), Dawei Ma (275249), Kai Long (2670919)   +2 more
core   +1 more source

Faculty of 1000 evaluation for The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo.

, 2018
S. Crowe
semanticscholar   +1 more source

Tryptophan‐Selective Chemical Modification of Peptides by Thioether‐Mediated Sulfenylation

ChemistryEurope
Chemical modification of biomolecules such as peptides and proteins is an important technology for the development of new functional molecules. Herein, a thioether‐mediated sulfenylation for tryptophan (Trp)‐selective chemical modification under mild ...
Hayate Shida, Akihiro Taguchi, Yuma Tokita, Yan Cui, Momoka Sakamaki, Sho Konno, Atsuhiko Taniguchi, Young Sook Yun, Yuuta Fujikawa, Hiroshi Kaneko, Hidemasa Nakaminami, Yoshio Hayashi   +11 more
doaj   +1 more source

Effects of additives on the prebiotic formation of depsipeptide oligomers, precursors of proto-polypeptides

, 2018
The process by which the first peptides were formed is still unclear. A few hypotheses have been proposed, but still there are doubts on whether they were possible during the prebiotic era.
Toro Arévalo, Kathyria M.
core  

Depsipeptide Analogues of Gly-Ala-Gly: Proton Localization and Effects on Collision-Induced Dissociation. [PDF]

J Am Soc Mass Spectrom
Shira BA, Herndon EC, DeMauro JE, Giuliano MW, Forsythe JG.   +4 more
europepmc   +1 more source

Linking molecular architecture to antibacterial functions: a chemical biology view of cyclic depsipeptides. [PDF]

Front Chem
Baravkar S, Thombare VJ, Wu Y, Patil NA.
europepmc   +1 more source

Geodiamolide A, a Marine Sponge Depsipeptide, Halts Proliferation and Triggers Cell Death in Squamous Cell Carcinoma (A431, NMSC) In Vitro. [PDF]

Int J Mol Sci
Rangel M, Ombredane AS, Azevedo RB, Fontes W, Joanitti GA, Castro MS.   +5 more
europepmc   +1 more source

Drug repurposing of natural depsipeptide from <i>Eleftheria terrae</i> isolated via iChip for anti-breast cancer therapy. [PDF]

Front Pharmacol
Fhatonah N, Rustandi T, Abdelmohsen UR, Rasydy OA, Ma'sum, Elghanam Y, Pashar I, Nordin, Mahal A, Riski A.   +9 more
europepmc   +1 more source

Marine Bioactive Peptides for Colorectal Cancer Therapy: Mechanisms, Therapeutic Potential, and Translational Challenges. [PDF]

Mar Drugs
Lu Y, Wang G, Zhou M, Chen T, Fan Z.
europepmc   +1 more source