Results 121 to 130 of about 5,696 (181)
Marine Natural Products in Preclinical Cancer Studies: Ten Years of Advanced Total Synthesis. [PDF]
Mar DrugsColarusso E +4 more
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Marine bioactive peptides with anticancer potential, a narrative review. [PDF]
Int J Biochem Mol BiolRafieezadeh D, Esfandyari G.
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Total Synthesis and Structural Reassignment of the Antitubercular Natural Product Evybactin. [PDF]
ChemistryLysenko V +9 more
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Mechanisms of aureobasidin A inhibition and drug resistance in a fungal IPC synthase complex. [PDF]
Nat CommunWu X, Gong X, Xie T.
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Chemistry - A European Journal, 2000
The convergent synthesis of a new class of chiral dendrimers is described. Owing to their structural resemblance to depsipeptides they are called depsipeptide dendrimers. The ex-chiral pool synthesis starts from (R,R)-, (S,S)-, and meso-tartaric acid as branching units and dipeptides or tripeptides consisting of glycine, (L)-alanine, and (L)-leucine as
J, Kress, A, Rosner, A, Hirsch
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The convergent synthesis of a new class of chiral dendrimers is described. Owing to their structural resemblance to depsipeptides they are called depsipeptide dendrimers. The ex-chiral pool synthesis starts from (R,R)-, (S,S)-, and meso-tartaric acid as branching units and dipeptides or tripeptides consisting of glycine, (L)-alanine, and (L)-leucine as
J, Kress, A, Rosner, A, Hirsch
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ChemInform, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Maciej, Stawikowski, Predrag, Cudic
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AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Maciej, Stawikowski, Predrag, Cudic
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Antimitotic Peptides and Depsipeptides
Current Medicinal Chemistry-Anti-Cancer Agents, 2012Tubulin is the target for an ever increasing number of unusual peptides and depsipeptides that were originally isolated from a wide variety of organisms. Since tubulin is the major component of cellular microtubules, which maintain cell shape in interphase and form the mitotic spindle, most of these compounds are highly toxic to mammalian cells.
Ernest, Hamel, David G, Covell
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The cyclization of peptides and depsipeptides
Journal of Peptide Science, 2003AbstractConstricting the peptide backbone into a more defined conformational form through cyclization is an activity evolved in nature and in synthetic work, the latter straddling only the most recent decades. The resulting conformational constraints increase the probability of an optimum response with bio‐receptors.
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Recent Developments in Depsipeptide Research
Current Medicinal Chemistry, 2002This review focuses on the major developments in depsipeptide research since 1995. Depsipeptides are bio-oligomers composed of hydroxy and amino acids linked by amide and ester bonds. Many depsipeptides show very promising biological activities, including anticancer, antibacterial, antiviral, antifungal, anti-inflammatory, and anti-clotting or anti ...
C E, Ballard, H, Yu, B, Wang
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Progress in Depsipeptide‐Based Biomaterials
Macromolecular Bioscience, 2010AbstractPolydepsipeptides – alternating copolymers of an α‐amino acid and an α‐hydroxy acid – are a group of biodegradable polymers. Versatile polydepsipeptides with or without pendant functional groups, as well as various polymer architectures, for example, providing alternative, random, diblock, triblock, multiblock or graft sequence structures, can ...
Yakai, Feng +3 more
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