Results 101 to 110 of about 9,955 (253)

A Convergent Synthesis of the Proposed Structure of Antitumor Depsipeptide Stereocalpin A

, 2016
The total synthesis of the proposed structure of anticancer agent stereocalpin A is described. The synthesis features a diastereoselective synthesis of a 5-hydroxy-2,4-dimethyl-3-oxooctanoic acid unit with asymmetric anti- and syn-aldol reactions as the ...
Chun-Xiao Xu (1955455), Arun K. Ghosh (468637)   +1 more
core   +3 more sources

Elucidation of novel turnagainolides and their biosynthetic gene cluster in Bacillus subtilis

Applied and Environmental Microbiology
Turnagainolides represent a unique class of cyclic depsipeptides characterized by the presence of a rare (E)-3-hydroxy-5-phenylpent-4-enoic acid (Hppa) residue, exhibiting diverse bioactivities.
Peng Li, Shuang Han, Min Wang, Xuejiao Zhang, Shuai Zhi, Meiling Jin, Jouni Jokela, Shan He, Liwei Liu   +8 more
doaj   +1 more source

A Concise Route to the Proposed Structure of Lydiamycin B, an Antimycobacterial Depsipeptide

, 2016
The total synthesis of four possible isomers with the proposed structure of antimycobacterial depsipeptide lydiamycin B is achieved. None of them shows identical NMR data with those reported for natural lydiamycin B, indicating that further structural ...
Dawei Ma (275249), Wenhua Li (426756), Jiangang Gan (2330944)   +2 more
core   +1 more source

Myxobacterial Depsipeptide Chondramides Interrupt SARS-CoV-2 Entry by Targeting Its Broad, Cell Tropic Spike Protein: Antagonistic Prospects for Anti-COVID-19 Drug Discovery

, 2021
The severity of the COVID-19 pandemic necessitated the search for drugs against the causative viral agent, SARS-CoV-2. Among the promising targets is the viral surface of SARS-CoV-2 adorned by spike proteins appearing as crown-like structures known for ...
Joe Anthony, Manzano, Von Novi, de Leon, Delfin Yñigo H., Pilapil, Omar, Villalobos, Mark Tristan J., Quimque, Kin Israel, Notarte, John Jeric P. San, Jose, Allan Patrick, Macabeo, Rey Arturo T., Fernandez   +8 more
core   +1 more source

Salinamide F, new depsipeptide antibiotic and inhibitor of bacterial RNA polymerase from a marine-derived Streptomyces sp

Journal of antibiotics (Tokyo. 1968), 2014
Salinamide F, new depsipeptide antibiotic and inhibitor of bacterial RNA polymerase from a marine-derived Streptomyces sp.
H. Hassan, David Degen, K. Jang, R. Ebright, W. Fenical   +4 more
semanticscholar   +1 more source

Prebiotic Organic Chemistry of Diketopiperazines

Asian Journal of Organic Chemistry, Volume 15, Issue 4, April 2026.
Diketopiperazines (DKPs) are considered essential in many life forms, but their prebiotic importance has not been fully understood. This review aims to discuss prebiotic organic chemistry for experimentally and computationally simulated reactions involving DKPs. ABSTRACT Even though the significance of amino acids and polypeptides is well recognized in
Jun Ohata
wiley   +1 more source

Advanced Methods for Detection of Bacillus cereus and Its Pathogenic Factors

Sensors, 2020
Bacillus cereus is an opportunistic foodborne pathogen causing food intoxication and infectious diseases. Different toxins and pathogenic factors are responsible for diarrheal syndrome, like nonhemolytic enterotoxin Nhe, hemolytic enterotoxin Hbl ...
Nalini Ramarao, Seav-Ly Tran, Marco Marin, Jasmina Vidic   +3 more
doaj   +1 more source

Total Syntheses of Depsipeptide Elastase Inhibitors YM-47141 and YM-47142 with use of Ylide Protection and Coupling Methods

, 2016
Total Syntheses of Depsipeptide Elastase Inhibitors YM-47141 and YM-47142 with use of Ylide Protection and Coupling ...
Jyun-Hung Chen (2994912), Harry H. Wasserman (2696116), Mingde Xia (2467906)   +2 more
core   +1 more source

Synthesis of Peptides, Peptide Nucleic Acid Components, and Other Biogenic Compounds From a Three‐Component Prebiotic Mixture

Chemistry – A European Journal, Volume 32, Issue 9, 2 March 2026.
High‐energy proton irradiation of a formamide–diaminomaleonitrile–glycine system in the presence of meteorites produces a broad spectrum of biogenic compounds, including nucleobases, nucleosides, peptides, and nucleobase–peptide conjugates, highlighting a chemically plausible prebiotic network.
Bruno Mattia Bizzarri, Rosangela Santalucia, Eleonora Mancin, Mikhail Kapralov, Eugene Krasavin, Raffaele Saladino, Ernesto Di Mauro   +6 more
wiley   +1 more source

Thailandepsin A

Acta Crystallographica Section E, 2011
Thailandepsin A [systematic name: (E)-(1S,5S,6R,9S,20R)-6-[(2S)-butan-2-yl]-5-hydroxy-20-[2-(methylsulfanyl)ethyl]-2-oxa-11,12-dithia-7,19,22-triazabicyclo[7.7.6]docosa-15-ene-3,8,18,21-tetraone], C23H37N3O6S3, is a newly reported [Wang et al. (2011). J.
Cheng Wang, Yi-Qiang Cheng
doaj   +1 more source