Results 111 to 120 of about 9,955 (253)
, 2004 Some unique features were disclosed during the structure elucidation of the cyclic depsipeptide hormaomycin (1), first isolated in 1989 from a Streptomyces griseoflavus strain and found to have quite an interesting spectrum of biological activities ...
de Meijere, Armin +1 more
core +1 more source
, 2007 The FK228 and spiruchostatin bicyclic depsipeptide natural products are among the most potent histone deacetylase (HDAC) inhibitors known. Although FK228 is in advanced clinical trials, the complexity of the natural products has precluded mechanistic ...
Packham, Graham +9 more
core +1 more source
FK228 from Burkholderia thailandensis MSMB43
Acta Crystallographica Section E, 2012 FK228 [systematic name: (1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-di(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone], C24H36N4O6S2, also known as FR901228, depsipeptide, NSC 630176, romidepsin, and ...
Xiang-Yang Liu +2 more
doaj +1 more source
, 2016 The FK228 and spiruchostatin bicyclic depsipeptide natural products are among the most potent histone deacetylase (HDAC) inhibitors known. Although FK228 is in advanced clinical trials, the complexity of the natural products has precluded mechanistic ...
Alexander Yurek-George (1748584) +9 more
core +1 more source
Genetically programmed cell-based synthesis of non-natural peptide and depsipeptide macrocycles.
, 2023 The direct genetically encoded cell-based synthesis of non-natural peptide and depsipeptide macrocycles is an outstanding challenge. Here we programme the encoded synthesis of 25 diverse non-natural macrocyclic peptides, each containing two non-canonical
core +1 more source
Szentiamide, an -formylated Cyclic Depsipeptide from DSM 16338
Natural Product Communications, 2011 Szentiamide ( 1 ) a new cyclic hexadepsipeptide was isolated from the culture broth of the entomopathogenic bacterium Xenorhabdus szentirmaii DSM 16338 T .
Birgit Ohlendorf +3 more
doaj +1 more source
Diastereoselective Assembly of Chiral RuII-Coordinated Depsipeptide-Dendrimers
, 2013 The synthesis, characterization and chiroptical properties of chiral dendrimers 11–14 formed by ruthenium coordination of2,2′-bipyridine (bpy*) ligands 4, 7, 8 and 10 involving two pairs of enantiomerically pure depsipeptide dendrons bound in 4,4 ...
Buschhaus, Boris, Hirsch, Andreas
core +1 more source
Kinetik und Mechanismus der selektiven Bindung von Ionen durch Cyclodepsipeptid-Antibiotika
CHIMIA, 1972 Stability constants for cation complexes of valinomycin and enniatin B were determined in methanol employing spectrophotometric titrations. Kinetic studies by relaxation methods led to the elucidation of the reaction mechanism of complex formation ...
Th. Funck, F. Eggers, E. Grell
doaj +1 more source
Kahalalide K: A New Cyclic Depsipeptide from the Hawaiian Green Alga Bryopsis Species
, 2016 Kahalalide K (1), a new cyclic depsipeptide, was isolated from the Hawaiian green alga Bryopsis sp. Kahalalide K was determined to possess a new array of three l- and three d-amino acids, including a 3-hydroxy-9-methyldecanoic acid that had been ...
Bryan Sakamoto (2348320) +4 more
core +1 more source
Journal of antibiotics (Tokyo. 1968), 2011 Romidepsin (Istodax), a selective inhibitor of histone deacetylases (HDACs), was approved for the treatment of cutaneous T-cell lymphoma in November 2009 by the US Food and Drug Administration.
K. Vandermolen +3 more
semanticscholar +1 more source